EA003181B1 - Антагонист хемокинового рецептора и циклоспорин в комбинированной терапии - Google Patents

Антагонист хемокинового рецептора и циклоспорин в комбинированной терапии Download PDF

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Publication number
EA003181B1
EA003181B1 EA200100366A EA200100366A EA003181B1 EA 003181 B1 EA003181 B1 EA 003181B1 EA 200100366 A EA200100366 A EA 200100366A EA 200100366 A EA200100366 A EA 200100366A EA 003181 B1 EA003181 B1 EA 003181B1
Authority
EA
Eurasian Patent Office
Prior art keywords
cyclosporin
receptor antagonist
chemokine receptor
pharmaceutical composition
cells
Prior art date
Application number
EA200100366A
Other languages
English (en)
Russian (ru)
Other versions
EA200100366A1 (ru
Inventor
Херманн-Йозеф Гроне
Питер Дж. Нельсон
Аманда Праудфут
Тимоти Н.С. Веллс
Original Assignee
Апплайд Резеч Системз Арс Холдинг Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Апплайд Резеч Системз Арс Холдинг Н.В. filed Critical Апплайд Резеч Системз Арс Холдинг Н.В.
Publication of EA200100366A1 publication Critical patent/EA200100366A1/ru
Publication of EA003181B1 publication Critical patent/EA003181B1/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EA200100366A 1998-09-18 1999-09-16 Антагонист хемокинового рецептора и циклоспорин в комбинированной терапии EA003181B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98117697A EP1000626A1 (en) 1998-09-18 1998-09-18 Chemokine receptor antagonist and cyclosporin in combined therapy
PCT/EP1999/006844 WO2000016796A1 (en) 1998-09-18 1999-09-16 Chemokine receptor antagonist and cyclosporin in combined therapy

Publications (2)

Publication Number Publication Date
EA200100366A1 EA200100366A1 (ru) 2001-08-27
EA003181B1 true EA003181B1 (ru) 2003-02-27

Family

ID=8232654

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200100366A EA003181B1 (ru) 1998-09-18 1999-09-16 Антагонист хемокинового рецептора и циклоспорин в комбинированной терапии

Country Status (23)

Country Link
US (1) US6902728B1 (enExample)
EP (2) EP1000626A1 (enExample)
JP (1) JP2003519082A (enExample)
KR (1) KR100613950B1 (enExample)
CN (1) CN1177613C (enExample)
AR (1) AR021810A1 (enExample)
AT (1) ATE227582T1 (enExample)
AU (1) AU766595B2 (enExample)
BR (1) BR9913846A (enExample)
CA (1) CA2344370A1 (enExample)
DE (1) DE69903964T2 (enExample)
DK (1) DK1113811T3 (enExample)
EA (1) EA003181B1 (enExample)
EE (1) EE04705B1 (enExample)
ES (1) ES2186411T3 (enExample)
HK (1) HK1041225B (enExample)
IL (2) IL141899A0 (enExample)
NO (1) NO20011371D0 (enExample)
PT (1) PT1113811E (enExample)
SI (1) SI1113811T1 (enExample)
UA (1) UA60379C2 (enExample)
WO (1) WO2000016796A1 (enExample)
ZA (1) ZA200101909B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7259136B2 (en) 1999-04-30 2007-08-21 Amylin Pharmaceuticals, Inc. Compositions and methods for treating peripheral vascular disease
US6740636B2 (en) 2000-07-31 2004-05-25 Schering Aktiengesellschaft Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
LT5132B (lt) 2000-07-31 2004-05-25 Schering Aktiengesellschaft Nepeptidiniai ccr1 receptorių antagonistai derinyje su ciklosporinu a širdies transplanto atmetimui gydyti
MX2010001307A (es) 2007-08-02 2010-07-30 Novimmune Sa Anticuerpos anti-proteína regulada con la activación, expresada y secretada por los linfocitos t normales y metodos de uso de los mismos.
JP6733968B2 (ja) * 2015-08-31 2020-08-05 日立化成株式会社 腎移植後合併症を評価するための分子法
JP6624704B2 (ja) 2015-08-31 2019-12-25 日立化成株式会社 尿路上皮疾患の評価のための分子法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2207036A1 (en) * 1994-12-08 1996-06-13 Glaxo Group Limited Rantes peptide and fragments and compositions comprising it for treatment of inflammation
AU712606B2 (en) * 1995-08-09 1999-11-11 Schering Corporation Combined use of interleukin-10 and cyclosporin for immunosuppression therapy
EP0927167A1 (en) * 1996-08-14 1999-07-07 Warner-Lambert Company 2-phenyl benzimidazole derivatives as mcp-1 antagonists
WO1998006751A1 (en) * 1996-08-16 1998-02-19 Research Corporation Technologies, Inc. Mcp-3, rantes and mip-1alpha receptor antagonists

Also Published As

Publication number Publication date
DE69903964T2 (de) 2003-03-27
SI1113811T1 (en) 2003-04-30
CA2344370A1 (en) 2000-03-30
CN1177613C (zh) 2004-12-01
EP1000626A1 (en) 2000-05-17
ZA200101909B (en) 2001-09-11
IL141899A0 (en) 2002-03-10
WO2000016796A1 (en) 2000-03-30
JP2003519082A (ja) 2003-06-17
ES2186411T3 (es) 2003-05-01
HK1041225A1 (en) 2002-07-05
NO20011371L (no) 2001-03-16
UA60379C2 (uk) 2003-10-15
IL141899A (en) 2007-12-03
AU6191499A (en) 2000-04-10
US6902728B1 (en) 2005-06-07
EP1113811B1 (en) 2002-11-13
HK1041225B (zh) 2005-04-22
KR100613950B1 (ko) 2006-08-18
KR20010075060A (ko) 2001-08-09
AR021810A1 (es) 2002-08-07
PT1113811E (pt) 2003-03-31
EE04705B1 (et) 2006-10-16
EA200100366A1 (ru) 2001-08-27
EP1113811A1 (en) 2001-07-11
EE200100159A (et) 2002-08-15
BR9913846A (pt) 2001-06-05
ATE227582T1 (de) 2002-11-15
DK1113811T3 (da) 2003-03-10
CN1319021A (zh) 2001-10-24
AU766595B2 (en) 2003-10-16
DE69903964D1 (en) 2002-12-19
NO20011371D0 (no) 2001-03-16

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Legal Events

Date Code Title Description
PC4A Registration of transfer of a eurasian patent by assignment
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU