PT1113811E - Antagonistas do receptor da quimiocina e ciclosporina em terapia combinada - Google Patents

Antagonistas do receptor da quimiocina e ciclosporina em terapia combinada

Info

Publication number
PT1113811E
PT1113811E PT99948760T PT99948760T PT1113811E PT 1113811 E PT1113811 E PT 1113811E PT 99948760 T PT99948760 T PT 99948760T PT 99948760 T PT99948760 T PT 99948760T PT 1113811 E PT1113811 E PT 1113811E
Authority
PT
Portugal
Prior art keywords
chemiocin
cyclosporine
antagonists
receptor
combined therapy
Prior art date
Application number
PT99948760T
Other languages
English (en)
Portuguese (pt)
Inventor
Hermann-Joseph Grone
Peter J Nelson
Amanda Proudfoot
Timothy N C Wells
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of PT1113811E publication Critical patent/PT1113811E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PT99948760T 1998-09-18 1999-09-16 Antagonistas do receptor da quimiocina e ciclosporina em terapia combinada PT1113811E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98117697A EP1000626A1 (en) 1998-09-18 1998-09-18 Chemokine receptor antagonist and cyclosporin in combined therapy

Publications (1)

Publication Number Publication Date
PT1113811E true PT1113811E (pt) 2003-03-31

Family

ID=8232654

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99948760T PT1113811E (pt) 1998-09-18 1999-09-16 Antagonistas do receptor da quimiocina e ciclosporina em terapia combinada

Country Status (23)

Country Link
US (1) US6902728B1 (enExample)
EP (2) EP1000626A1 (enExample)
JP (1) JP2003519082A (enExample)
KR (1) KR100613950B1 (enExample)
CN (1) CN1177613C (enExample)
AR (1) AR021810A1 (enExample)
AT (1) ATE227582T1 (enExample)
AU (1) AU766595B2 (enExample)
BR (1) BR9913846A (enExample)
CA (1) CA2344370A1 (enExample)
DE (1) DE69903964T2 (enExample)
DK (1) DK1113811T3 (enExample)
EA (1) EA003181B1 (enExample)
EE (1) EE04705B1 (enExample)
ES (1) ES2186411T3 (enExample)
HK (1) HK1041225B (enExample)
IL (2) IL141899A0 (enExample)
NO (1) NO20011371L (enExample)
PT (1) PT1113811E (enExample)
SI (1) SI1113811T1 (enExample)
UA (1) UA60379C2 (enExample)
WO (1) WO2000016796A1 (enExample)
ZA (1) ZA200101909B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7259136B2 (en) 1999-04-30 2007-08-21 Amylin Pharmaceuticals, Inc. Compositions and methods for treating peripheral vascular disease
US6740636B2 (en) * 2000-07-31 2004-05-25 Schering Aktiengesellschaft Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
LT5132B (lt) 2000-07-31 2004-05-25 Schering Aktiengesellschaft Nepeptidiniai ccr1 receptorių antagonistai derinyje su ciklosporinu a širdies transplanto atmetimui gydyti
EP2185719B1 (en) 2007-08-02 2013-11-13 NovImmune SA Anti-rantes antibodies and methods of use thereof
WO2017040515A1 (en) * 2015-08-31 2017-03-09 Hitachi Chemical Co., Ltd. Molecular methods for assessing post kidney transplant complications
JP6624704B2 (ja) 2015-08-31 2019-12-25 日立化成株式会社 尿路上皮疾患の評価のための分子法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU221089B1 (en) * 1994-12-08 2002-08-28 Glaxo Group Ltd Rantes peptide derivates with antagonistic effect and uses thereof
EP0845994A1 (en) * 1995-08-09 1998-06-10 Schering Corporation Combined use of interleukin-10 and cyclosporin for immunosuppression therapy
US6184235B1 (en) * 1996-08-14 2001-02-06 Warner-Lambert Company 2-phenyl benzimidazole derivatives as MCP-1 antagonists
WO1998006751A1 (en) * 1996-08-16 1998-02-19 Research Corporation Technologies, Inc. Mcp-3, rantes and mip-1alpha receptor antagonists

Also Published As

Publication number Publication date
NO20011371D0 (no) 2001-03-16
US6902728B1 (en) 2005-06-07
CA2344370A1 (en) 2000-03-30
EE04705B1 (et) 2006-10-16
AU6191499A (en) 2000-04-10
EA200100366A1 (ru) 2001-08-27
BR9913846A (pt) 2001-06-05
EP1000626A1 (en) 2000-05-17
DE69903964D1 (en) 2002-12-19
SI1113811T1 (en) 2003-04-30
KR100613950B1 (ko) 2006-08-18
EA003181B1 (ru) 2003-02-27
CN1177613C (zh) 2004-12-01
KR20010075060A (ko) 2001-08-09
JP2003519082A (ja) 2003-06-17
EE200100159A (et) 2002-08-15
DK1113811T3 (da) 2003-03-10
ZA200101909B (en) 2001-09-11
ATE227582T1 (de) 2002-11-15
CN1319021A (zh) 2001-10-24
EP1113811B1 (en) 2002-11-13
IL141899A0 (en) 2002-03-10
HK1041225B (zh) 2005-04-22
IL141899A (en) 2007-12-03
NO20011371L (no) 2001-03-16
AU766595B2 (en) 2003-10-16
AR021810A1 (es) 2002-08-07
ES2186411T3 (es) 2003-05-01
UA60379C2 (uk) 2003-10-15
WO2000016796A1 (en) 2000-03-30
DE69903964T2 (de) 2003-03-27
HK1041225A1 (en) 2002-07-05
EP1113811A1 (en) 2001-07-11

Similar Documents

Publication Publication Date Title
DE69824175D1 (de) Nachfüllbarer stent und verabreichungssystem
NL300395I2 (nl) GnRH antagonisten gemodificeerd in posities 5 en 6
DE10080052T1 (de) Beratungshilfeverfahren und -einrichtungen
ID22565A (id) Penggunaan nanodispersi dalam formulasi akhir obat
DE69835251D1 (de) TMR Stent und zugehöriges Einführsystem
DE69913507D1 (de) Netzstent und stenteinführungssystem
PT796855E (pt) Inibicao da reabsorcao nos ossos e antagonistas de vitronectina
EE200100372A (et) TWEAK-valgu ja TWEAK-valgu retseptori antagonistid ja nende kasutamine immuunhaiguste raviks
EE9900572A (et) Struktuur koormuse jaotuseks arvutivõrkudes
NO994438D0 (no) Terapeutisk aktive diarylpropylaminer samt fremstilling og anvendelse derav
DE69831750D1 (de) Biozide und biozide tücher
PT9373T (pt) Almofada e colchao anatomicos
NO994665L (no) Immobiliserte og aktivitetsstabiliserte komplekser av LHRH-antagonister og fremgangsmÕter for deres fremstilling
ATE227724T1 (de) Muscarinagonisten und antagonisten
NO20004274D0 (no) Proteaseaktivert reseptor 4 og anvendelse derav
HUP0202048A3 (en) Use of alpha1betha1 integrin receptor inhibitors and tgf-betha1 inhibitors in the treatment of kidney disease
NO20000462L (no) 4-okso-3,5-dihydro-4H-pyridazino[4,5-b]indol-1-acetamid derivater, deres fremstilling og deres anvendelse i terapi
PT1178981E (pt) 3-piridil-4-arilpirrois substituidos e metodos terapeuticos e profilacticos
DK1113811T3 (da) Kemokinreceptorantagonist og cyclosporin i kombineret terapi
DK0815126T3 (da) Bicykliske tachykinin-antagonister, fremstilling deraf og deres anvendelse i farmaceutiske præparater
IL129546A0 (en) N-(imidazolylbutyl)benzenesulphonamide derivatives their preparation and their application in therapeutics
ZA982355B (en) Derivatives of n-(arginyl) benzenesulphonamide their preparation and their use in therapy
ID27282A (id) Protein c polipeptida pada manusia
BR7703063U (pt) Disposição aplicada em cinzeiros e similares
IS5718A (is) Notkun alfa1ß1 integrín viðtaka hindra og TGF-ß1 hindra í meðferð nýrnasjúkdóma