JP2003519082A - ケモカイン受容体アンタゴニストとシクロスポリンを組み合わせた治療 - Google Patents

ケモカイン受容体アンタゴニストとシクロスポリンを組み合わせた治療

Info

Publication number
JP2003519082A
JP2003519082A JP2000573757A JP2000573757A JP2003519082A JP 2003519082 A JP2003519082 A JP 2003519082A JP 2000573757 A JP2000573757 A JP 2000573757A JP 2000573757 A JP2000573757 A JP 2000573757A JP 2003519082 A JP2003519082 A JP 2003519082A
Authority
JP
Japan
Prior art keywords
rantes
receptor antagonist
chemokine receptor
cells
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000573757A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003519082A5 (enExample
Inventor
グローネ，ヘルマン−ヨーゼフ
ネルソン，ピーター・ジェイ
プラウドフット，アマンダ
ウェルズ，ティモシー・エヌ・シー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Research Systems ARS Holding NV
Original Assignee
Applied Research Systems ARS Holding NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems ARS Holding NV filed Critical Applied Research Systems ARS Holding NV
Publication of JP2003519082A publication Critical patent/JP2003519082A/ja
Publication of JP2003519082A5 publication Critical patent/JP2003519082A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2000573757A 1998-09-18 1999-09-16 ケモカイン受容体アンタゴニストとシクロスポリンを組み合わせた治療 Withdrawn JP2003519082A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98117697.7 1998-09-18
EP98117697A EP1000626A1 (en) 1998-09-18 1998-09-18 Chemokine receptor antagonist and cyclosporin in combined therapy
PCT/EP1999/006844 WO2000016796A1 (en) 1998-09-18 1999-09-16 Chemokine receptor antagonist and cyclosporin in combined therapy

Publications (2)

Publication Number Publication Date
JP2003519082A true JP2003519082A (ja) 2003-06-17
JP2003519082A5 JP2003519082A5 (enExample) 2006-05-25

Family

ID=8232654

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000573757A Withdrawn JP2003519082A (ja) 1998-09-18 1999-09-16 ケモカイン受容体アンタゴニストとシクロスポリンを組み合わせた治療

Country Status (23)

Country Link
US (1) US6902728B1 (enExample)
EP (2) EP1000626A1 (enExample)
JP (1) JP2003519082A (enExample)
KR (1) KR100613950B1 (enExample)
CN (1) CN1177613C (enExample)
AR (1) AR021810A1 (enExample)
AT (1) ATE227582T1 (enExample)
AU (1) AU766595B2 (enExample)
BR (1) BR9913846A (enExample)
CA (1) CA2344370A1 (enExample)
DE (1) DE69903964T2 (enExample)
DK (1) DK1113811T3 (enExample)
EA (1) EA003181B1 (enExample)
EE (1) EE04705B1 (enExample)
ES (1) ES2186411T3 (enExample)
HK (1) HK1041225B (enExample)
IL (2) IL141899A0 (enExample)
NO (1) NO20011371L (enExample)
PT (1) PT1113811E (enExample)
SI (1) SI1113811T1 (enExample)
UA (1) UA60379C2 (enExample)
WO (1) WO2000016796A1 (enExample)
ZA (1) ZA200101909B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018143243A (ja) * 2015-08-31 2018-09-20 日立化成株式会社 腎移植後合併症を評価するための分子法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7259136B2 (en) 1999-04-30 2007-08-21 Amylin Pharmaceuticals, Inc. Compositions and methods for treating peripheral vascular disease
US6740636B2 (en) * 2000-07-31 2004-05-25 Schering Aktiengesellschaft Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
LT5132B (lt) 2000-07-31 2004-05-25 Schering Aktiengesellschaft Nepeptidiniai ccr1 receptorių antagonistai derinyje su ciklosporinu a širdies transplanto atmetimui gydyti
EP2185719B1 (en) 2007-08-02 2013-11-13 NovImmune SA Anti-rantes antibodies and methods of use thereof
JP6624704B2 (ja) 2015-08-31 2019-12-25 日立化成株式会社 尿路上皮疾患の評価のための分子法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU221089B1 (en) * 1994-12-08 2002-08-28 Glaxo Group Ltd Rantes peptide derivates with antagonistic effect and uses thereof
EP0845994A1 (en) * 1995-08-09 1998-06-10 Schering Corporation Combined use of interleukin-10 and cyclosporin for immunosuppression therapy
US6184235B1 (en) * 1996-08-14 2001-02-06 Warner-Lambert Company 2-phenyl benzimidazole derivatives as MCP-1 antagonists
WO1998006751A1 (en) * 1996-08-16 1998-02-19 Research Corporation Technologies, Inc. Mcp-3, rantes and mip-1alpha receptor antagonists

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018143243A (ja) * 2015-08-31 2018-09-20 日立化成株式会社 腎移植後合併症を評価するための分子法

Also Published As

Publication number Publication date
PT1113811E (pt) 2003-03-31
NO20011371D0 (no) 2001-03-16
US6902728B1 (en) 2005-06-07
CA2344370A1 (en) 2000-03-30
EE04705B1 (et) 2006-10-16
AU6191499A (en) 2000-04-10
EA200100366A1 (ru) 2001-08-27
BR9913846A (pt) 2001-06-05
EP1000626A1 (en) 2000-05-17
DE69903964D1 (en) 2002-12-19
SI1113811T1 (en) 2003-04-30
KR100613950B1 (ko) 2006-08-18
EA003181B1 (ru) 2003-02-27
CN1177613C (zh) 2004-12-01
KR20010075060A (ko) 2001-08-09
EE200100159A (et) 2002-08-15
DK1113811T3 (da) 2003-03-10
ZA200101909B (en) 2001-09-11
ATE227582T1 (de) 2002-11-15
CN1319021A (zh) 2001-10-24
EP1113811B1 (en) 2002-11-13
IL141899A0 (en) 2002-03-10
HK1041225B (zh) 2005-04-22
IL141899A (en) 2007-12-03
NO20011371L (no) 2001-03-16
AU766595B2 (en) 2003-10-16
AR021810A1 (es) 2002-08-07
ES2186411T3 (es) 2003-05-01
UA60379C2 (uk) 2003-10-15
WO2000016796A1 (en) 2000-03-30
DE69903964T2 (de) 2003-03-27
HK1041225A1 (en) 2002-07-05
EP1113811A1 (en) 2001-07-11

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