HK1041225B - 聯合治療中的趨化因子受體拮抗劑和環孢菌素 - Google Patents

聯合治療中的趨化因子受體拮抗劑和環孢菌素 Download PDF

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Publication number
HK1041225B
HK1041225B HK02103034.0A HK02103034A HK1041225B HK 1041225 B HK1041225 B HK 1041225B HK 02103034 A HK02103034 A HK 02103034A HK 1041225 B HK1041225 B HK 1041225B
Authority
HK
Hong Kong
Prior art keywords
rantes
cyclosporin
met
cells
kidney
Prior art date
Application number
HK02103034.0A
Other languages
English (en)
Chinese (zh)
Other versions
HK1041225A1 (en
Inventor
J‧格罗纳 H‧-
J‧格羅納 H‧-
P‧J‧纳尔逊
A‧普劳德富特
P‧J‧納爾遜
T‧N‧C‧韦尔斯
A‧普勞德富特
T‧N‧C‧韋爾斯
Original Assignee
Laboratoires Serono S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Serono S.A. filed Critical Laboratoires Serono S.A.
Publication of HK1041225A1 publication Critical patent/HK1041225A1/xx
Publication of HK1041225B publication Critical patent/HK1041225B/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HK02103034.0A 1998-09-18 1999-09-16 聯合治療中的趨化因子受體拮抗劑和環孢菌素 HK1041225B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98117697.7 1998-09-18
EP98117697A EP1000626A1 (en) 1998-09-18 1998-09-18 Chemokine receptor antagonist and cyclosporin in combined therapy
PCT/EP1999/006844 WO2000016796A1 (en) 1998-09-18 1999-09-16 Chemokine receptor antagonist and cyclosporin in combined therapy

Publications (2)

Publication Number Publication Date
HK1041225A1 HK1041225A1 (en) 2002-07-05
HK1041225B true HK1041225B (zh) 2005-04-22

Family

ID=8232654

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02103034.0A HK1041225B (zh) 1998-09-18 1999-09-16 聯合治療中的趨化因子受體拮抗劑和環孢菌素

Country Status (23)

Country Link
US (1) US6902728B1 (enExample)
EP (2) EP1000626A1 (enExample)
JP (1) JP2003519082A (enExample)
KR (1) KR100613950B1 (enExample)
CN (1) CN1177613C (enExample)
AR (1) AR021810A1 (enExample)
AT (1) ATE227582T1 (enExample)
AU (1) AU766595B2 (enExample)
BR (1) BR9913846A (enExample)
CA (1) CA2344370A1 (enExample)
DE (1) DE69903964T2 (enExample)
DK (1) DK1113811T3 (enExample)
EA (1) EA003181B1 (enExample)
EE (1) EE04705B1 (enExample)
ES (1) ES2186411T3 (enExample)
HK (1) HK1041225B (enExample)
IL (2) IL141899A0 (enExample)
NO (1) NO20011371L (enExample)
PT (1) PT1113811E (enExample)
SI (1) SI1113811T1 (enExample)
UA (1) UA60379C2 (enExample)
WO (1) WO2000016796A1 (enExample)
ZA (1) ZA200101909B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7259136B2 (en) 1999-04-30 2007-08-21 Amylin Pharmaceuticals, Inc. Compositions and methods for treating peripheral vascular disease
US6740636B2 (en) * 2000-07-31 2004-05-25 Schering Aktiengesellschaft Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
LT5132B (lt) 2000-07-31 2004-05-25 Schering Aktiengesellschaft Nepeptidiniai ccr1 receptorių antagonistai derinyje su ciklosporinu a širdies transplanto atmetimui gydyti
EP2185719B1 (en) 2007-08-02 2013-11-13 NovImmune SA Anti-rantes antibodies and methods of use thereof
WO2017040515A1 (en) * 2015-08-31 2017-03-09 Hitachi Chemical Co., Ltd. Molecular methods for assessing post kidney transplant complications
JP6624704B2 (ja) 2015-08-31 2019-12-25 日立化成株式会社 尿路上皮疾患の評価のための分子法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU221089B1 (en) * 1994-12-08 2002-08-28 Glaxo Group Ltd Rantes peptide derivates with antagonistic effect and uses thereof
EP0845994A1 (en) * 1995-08-09 1998-06-10 Schering Corporation Combined use of interleukin-10 and cyclosporin for immunosuppression therapy
US6184235B1 (en) * 1996-08-14 2001-02-06 Warner-Lambert Company 2-phenyl benzimidazole derivatives as MCP-1 antagonists
WO1998006751A1 (en) * 1996-08-16 1998-02-19 Research Corporation Technologies, Inc. Mcp-3, rantes and mip-1alpha receptor antagonists

Also Published As

Publication number Publication date
PT1113811E (pt) 2003-03-31
NO20011371D0 (no) 2001-03-16
US6902728B1 (en) 2005-06-07
CA2344370A1 (en) 2000-03-30
EE04705B1 (et) 2006-10-16
AU6191499A (en) 2000-04-10
EA200100366A1 (ru) 2001-08-27
BR9913846A (pt) 2001-06-05
EP1000626A1 (en) 2000-05-17
DE69903964D1 (en) 2002-12-19
SI1113811T1 (en) 2003-04-30
KR100613950B1 (ko) 2006-08-18
EA003181B1 (ru) 2003-02-27
CN1177613C (zh) 2004-12-01
KR20010075060A (ko) 2001-08-09
JP2003519082A (ja) 2003-06-17
EE200100159A (et) 2002-08-15
DK1113811T3 (da) 2003-03-10
ZA200101909B (en) 2001-09-11
ATE227582T1 (de) 2002-11-15
CN1319021A (zh) 2001-10-24
EP1113811B1 (en) 2002-11-13
IL141899A0 (en) 2002-03-10
IL141899A (en) 2007-12-03
NO20011371L (no) 2001-03-16
AU766595B2 (en) 2003-10-16
AR021810A1 (es) 2002-08-07
ES2186411T3 (es) 2003-05-01
UA60379C2 (uk) 2003-10-15
WO2000016796A1 (en) 2000-03-30
DE69903964T2 (de) 2003-03-27
HK1041225A1 (en) 2002-07-05
EP1113811A1 (en) 2001-07-11

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Free format text: CORRECTION OF THE CHINESE NAME OF INVENTOR FROM H

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090916