KR100589990B1 - Ｉｐ 길항제인 알콕시카보닐아미노 헤테로아릴 카복실산유도체 - Google Patents

Ｉｐ 길항제인 알콕시카보닐아미노 헤테로아릴 카복실산유도체 Download PDF

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Publication number
KR100589990B1
KR100589990B1 KR1020037011464A KR20037011464A KR100589990B1 KR 100589990 B1 KR100589990 B1 KR 100589990B1 KR 1020037011464 A KR1020037011464 A KR 1020037011464A KR 20037011464 A KR20037011464 A KR 20037011464A KR 100589990 B1 KR100589990 B1 KR 100589990B1
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South Korea
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formula
phenyl
group
compounds
carboxylic acid
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KR1020037011464A
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English (en)
Korean (ko)
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KR20030078962A (ko
Inventor
로페즈-타피아프란시스코자비어
니짠도브
오양카운드
Original Assignee
에프. 호프만-라 로슈 아게
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020037011464A 2001-03-02 2002-02-25 Ｉｐ 길항제인 알콕시카보닐아미노 헤테로아릴 카복실산유도체 Expired - Fee Related KR100589990B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27284901P 2001-03-02 2001-03-02
US60/272,849 2001-03-02
PCT/EP2002/001942 WO2002070514A1 (en) 2001-03-02 2002-02-25 Alkoxycarbonylamino heteroaryl carboxylic acid derivatives as ip antagonists

Publications (2)

Publication Number Publication Date
KR20030078962A KR20030078962A (ko) 2003-10-08
KR100589990B1 true KR100589990B1 (ko) 2006-06-15

Family

ID=23041569

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020037011464A Expired - Fee Related KR100589990B1 (ko) 2001-03-02 2002-02-25 Ｉｐ 길항제인 알콕시카보닐아미노 헤테로아릴 카복실산유도체

Country Status (14)

Country Link
US (1) US6569860B2 (enExample)
EP (1) EP1368345B1 (enExample)
JP (1) JP2004526721A (enExample)
KR (1) KR100589990B1 (enExample)
CN (1) CN1280289C (enExample)
AR (1) AR033429A1 (enExample)
AT (1) ATE321041T1 (enExample)
BR (1) BR0207730A (enExample)
CA (1) CA2438813C (enExample)
DE (1) DE60210058T2 (enExample)
ES (1) ES2260425T3 (enExample)
MX (1) MXPA03007864A (enExample)
WO (1) WO2002070514A1 (enExample)
ZA (1) ZA200306283B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040054008A1 (en) * 2002-09-13 2004-03-18 Tohru Araki Medicament for treatment of nocturia
EP1596858A1 (en) * 2003-02-14 2005-11-23 Medical Research Council Ip receptor antagonists for the treatment of pathological uterine conditions
KR100840114B1 (ko) * 2005-10-20 2008-06-19 주식회사 엘지화학 점착제 조성물
US7262313B2 (en) * 2005-10-20 2007-08-28 Lg Chem, Ltd. Organic silane compound
AR069650A1 (es) * 2007-12-14 2010-02-10 Actelion Pharmaceuticals Ltd Derivados de aminopirazol como agonistas no peptidicos del receptor alx humano
US9295665B2 (en) 2013-03-12 2016-03-29 Allergan, Inc. Inhibition of neovascularization by simultaneous inhibition of prostanoid IP and EP4 receptors
US9321745B2 (en) * 2013-03-12 2016-04-26 Allergan, Inc. Inhibition of neovascularization by inhibition of prostanoid IP receptors
CN112074505B (zh) 2018-03-08 2024-04-05 因赛特公司 作为PI3K-γ抑制剂的氨基吡嗪二醇化合物
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors
EP4119138A1 (en) * 2021-07-12 2023-01-18 Universität Hamburg Dhodh inhibitors and their use as antiviral agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5908842A (en) 1995-12-08 1999-06-01 Merck & Co., Inc. Substituted 2-acylamino-pyridines as inhibitors of nitric oxide synthase
US6184242B1 (en) 1997-09-04 2001-02-06 Syntex Usa (Llc) 2-(substituted-phenyl)amino-imidazoline derivatives
WO1999026925A1 (en) * 1997-11-26 1999-06-03 Yoshitomi Pharmaceutical Industries, Ltd. Tryptase inhibitors comprising heterocyclic amide compounds
RU2235095C2 (ru) * 1998-10-06 2004-08-27 Дайниппон Фармасьютикал Ко., Лтд. 2,3-дизамещенное производное пиридина, способы его получения, содержащая его фармацевтическая композиция и промежуточный продукт для его получения
US6335459B1 (en) * 1998-12-23 2002-01-01 Syntex (U.S.A.) Llc Aryl carboxylic acid and aryl tetrazole derivatives as IP receptor modulators
HUP0203542A3 (en) * 1999-08-12 2003-07-28 Upjohn Co 3(5)-amino-pyrazole derivatives, process for their preparation, their use and pharmaceutical compositions containing the same
KR100523119B1 (ko) * 2000-03-16 2005-10-20 에프. 호프만-라 로슈 아게 Ｉｐ 길항제로서의 카복실산 유도체

Also Published As

Publication number Publication date
ZA200306283B (en) 2004-11-15
CA2438813C (en) 2008-07-29
CN1280289C (zh) 2006-10-18
KR20030078962A (ko) 2003-10-08
MXPA03007864A (es) 2003-12-04
EP1368345A1 (en) 2003-12-10
ATE321041T1 (de) 2006-04-15
JP2004526721A (ja) 2004-09-02
US6569860B2 (en) 2003-05-27
ES2260425T3 (es) 2006-11-01
AR033429A1 (es) 2003-12-17
DE60210058D1 (de) 2006-05-11
WO2002070514A1 (en) 2002-09-12
BR0207730A (pt) 2004-03-23
DE60210058T2 (de) 2006-11-09
CA2438813A1 (en) 2002-09-12
US20020169171A1 (en) 2002-11-14
EP1368345B1 (en) 2006-03-22
CN1494544A (zh) 2004-05-05

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