KR100542536B1 - 지도부딘,1592u89및3tc또는ftc의상승작용성복합제제 - Google Patents

지도부딘,1592u89및3tc또는ftc의상승작용성복합제제 Download PDF

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Publication number
KR100542536B1
KR100542536B1 KR1019970706824A KR19970706824A KR100542536B1 KR 100542536 B1 KR100542536 B1 KR 100542536B1 KR 1019970706824 A KR1019970706824 A KR 1019970706824A KR 19970706824 A KR19970706824 A KR 19970706824A KR 100542536 B1 KR100542536 B1 KR 100542536B1
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KR
South Korea
Prior art keywords
formulation
amino
cis
zidovudine
ftc
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Expired - Lifetime
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KR1019970706824A
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English (en)
Korean (ko)
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KR19980703420A (ko
Inventor
데이비드 월터 바리
마르타 헤이더 에스티. 클레어
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더 웰컴 파운데이션 리미티드
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26306774&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100542536(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9506490.3A external-priority patent/GB9506490D0/en
Priority claimed from GBGB9506489.5A external-priority patent/GB9506489D0/en
Application filed by 더 웰컴 파운데이션 리미티드 filed Critical 더 웰컴 파운데이션 리미티드
Publication of KR19980703420A publication Critical patent/KR19980703420A/ko
Application granted granted Critical
Publication of KR100542536B1 publication Critical patent/KR100542536B1/ko
Assigned to 비이브 헬쓰케어 유케이 리미티드 reassignment 비이브 헬쓰케어 유케이 리미티드 권리의 전부이전등록 Assignors: 글락소 그룹 리미티드
Assigned to 글락소 그룹 리미티드 reassignment 글락소 그룹 리미티드 권리의 전부이전등록 Assignors: 더 웰컴 파운데이션 리미티드
Anticipated expiration legal-status Critical
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cephalosporin Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicinal Preparation (AREA)
KR1019970706824A 1995-03-30 1996-03-28 지도부딘,1592u89및3tc또는ftc의상승작용성복합제제 Expired - Lifetime KR100542536B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9506490.3A GB9506490D0 (en) 1995-03-30 1995-03-30 Antiviral combinations
GB9506490.3 1995-03-30
GBGB9506489.5A GB9506489D0 (en) 1995-03-30 1995-03-30 Antiviral combinations
GB9506489.5 1995-03-30

Publications (2)

Publication Number Publication Date
KR19980703420A KR19980703420A (ko) 1998-11-05
KR100542536B1 true KR100542536B1 (ko) 2006-03-23

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KR1019970706824A Expired - Lifetime KR100542536B1 (ko) 1995-03-30 1996-03-28 지도부딘,1592u89및3tc또는ftc의상승작용성복합제제

Country Status (35)

Country Link
US (1) US6417191B1 (cg-RX-API-DMAC7.html)
EP (1) EP0817637B1 (cg-RX-API-DMAC7.html)
JP (1) JP2954357B2 (cg-RX-API-DMAC7.html)
KR (1) KR100542536B1 (cg-RX-API-DMAC7.html)
CN (1) CN1103593C (cg-RX-API-DMAC7.html)
AP (1) AP652A (cg-RX-API-DMAC7.html)
AT (1) ATE220551T1 (cg-RX-API-DMAC7.html)
AU (1) AU715213B2 (cg-RX-API-DMAC7.html)
BR (3) BRPI9607851B8 (cg-RX-API-DMAC7.html)
CA (1) CA2216634C (cg-RX-API-DMAC7.html)
CZ (1) CZ295940B6 (cg-RX-API-DMAC7.html)
DE (3) DE69622386T2 (cg-RX-API-DMAC7.html)
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EA (1) EA000626B3 (cg-RX-API-DMAC7.html)
EE (1) EE04047B1 (cg-RX-API-DMAC7.html)
ES (1) ES2179193T3 (cg-RX-API-DMAC7.html)
FR (1) FR05C0022I2 (cg-RX-API-DMAC7.html)
GE (1) GEP20022647B (cg-RX-API-DMAC7.html)
HU (1) HU224010B1 (cg-RX-API-DMAC7.html)
IL (1) IL117727A (cg-RX-API-DMAC7.html)
LU (1) LU91171I2 (cg-RX-API-DMAC7.html)
MX (1) MX9707316A (cg-RX-API-DMAC7.html)
MY (1) MY115461A (cg-RX-API-DMAC7.html)
NL (1) NL300195I2 (cg-RX-API-DMAC7.html)
NO (2) NO313787B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ306419A (cg-RX-API-DMAC7.html)
OA (1) OA10616A (cg-RX-API-DMAC7.html)
PL (1) PL187085B1 (cg-RX-API-DMAC7.html)
PT (1) PT817637E (cg-RX-API-DMAC7.html)
RO (1) RO117995B1 (cg-RX-API-DMAC7.html)
SI (1) SI0817637T1 (cg-RX-API-DMAC7.html)
SK (1) SK283825B6 (cg-RX-API-DMAC7.html)
TR (1) TR199701074T1 (cg-RX-API-DMAC7.html)
UA (1) UA60293C2 (cg-RX-API-DMAC7.html)
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KR20000022226A (ko) * 1996-06-25 2000-04-25 그레이엄 브레레톤;레슬리 에드워즈 Hiv 치료에 사용하기 위한 vx478, 지도부딘, ftc 및(또는) 3tc를 포함하는 배합물
US6113920A (en) * 1996-10-31 2000-09-05 Glaxo Wellcome Inc. Pharmaceutical compositions
TW536403B (en) * 1997-03-24 2003-06-11 Glaxo Group Ltd An ethanol and ethylenediaminetetraacetic acid free pharmaceutical composition comprising lamivudine and exhibiting antimicrobial preservative efficacy
BR9809127A (pt) * 1997-05-17 2000-08-01 Glaxo Group Ltd Combinação, formulação farmacêutica, processo para o tratamento de uma infecção por hiv em um animal infectado, uso de (-) -(1s,4r)-4-[2-amino-6-(ciclopropil amino)-9h-purin-9-il)-2-ciclopenteno-1-metanol, e, pacote de paciente
GB9709945D0 (en) * 1997-05-17 1997-07-09 Glaxo Group Ltd A novel salt
AU769660B2 (en) * 1997-05-17 2004-01-29 Glaxo Group Limited Carbocyclic nucleoside hemisulfate and its use in treating viral infections
GB9809213D0 (en) * 1998-04-29 1998-07-01 Glaxo Group Ltd Pharmaceutical compositions
AU4219799A (en) * 1998-05-29 1999-12-13 University Of Florida Combination therapy for treatment of fiv infection
US6875773B1 (en) 1998-05-29 2005-04-05 Ben M. Dunn Combination therapy for treatment of FIV infection
GB9820417D0 (en) * 1998-09-18 1998-11-11 Glaxo Group Ltd Antiviral combinations
US6432966B2 (en) 1999-10-29 2002-08-13 Smithkline Beecham Corporation Antiviral combinations
US7074417B2 (en) * 2000-10-13 2006-07-11 Advancis Pharmaceutical Corporation Multiple-delayed release anti-viral product, use and formulation thereof
AP2220A (en) * 2001-05-11 2011-03-24 Cipla Medpro Pty Ltd Pharmaceutical composition.
TW200403061A (en) * 2002-06-04 2004-03-01 Glaxo Group Ltd Pharmaceutical compositions
PT1583542E (pt) 2003-01-14 2008-09-17 Gilead Sciences Inc Composições e métodos para terapia de combinação antiviral
WO2004085406A1 (en) 2003-03-24 2004-10-07 F. Hoffmann-La Roche Ag Benzyl-pyridazinons as reverse transcriptase inhibitors
BRPI0415533A (pt) 2003-10-24 2006-12-26 Immunaid Pty Ltd método de terapia
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
EP1940781A1 (en) 2005-10-19 2008-07-09 F.Hoffmann-La Roche Ag Phenyl-acetamide nnrt inhibitors
ES2550152T3 (es) 2006-12-13 2015-11-04 F. Hoffmann-La Roche Ag Derivados de 2-(piperidin-4-il)-4-fenoxi-o fenilamino-pirimidina como inhibidores no nucleósidos de transcriptasa inversa
CA2677623C (en) * 2007-02-09 2015-04-07 Alphapharm Pty Ltd A dosage form containing two or more active pharmaceutical ingredients in different physical forms
DK2435825T3 (en) 2009-05-27 2015-10-19 Biotempus Ltd Modes for medical care
EP3351249A1 (en) 2010-01-27 2018-07-25 VIIV Healthcare Company Antiviral therapy
HK1220390A1 (zh) 2013-08-29 2017-05-05 Teva Pharmaceutical Industries Ltd. 包括恩曲他滨，替诺福韦，达芦那韦和利托那韦的单位剂型以及包含达芦那韦和利托那韦的单体片剂
EP3129009A1 (en) 2014-04-08 2017-02-15 Teva Pharmaceutical Industries Ltd Unit dosage form comprising emtricitabine, tenofovir, darunavir and ritonavir
CN117164657A (zh) 2014-08-12 2023-12-05 莫纳什大学 定向淋巴的前药
CN118063537A (zh) 2015-09-08 2024-05-24 莫纳什大学 定向淋巴的前药
EP4306524A3 (en) 2017-08-29 2024-09-11 PureTech LYT, Inc. Lymphatic system-directing lipid prodrugs
US11883497B2 (en) 2017-08-29 2024-01-30 Puretech Lyt, Inc. Lymphatic system-directing lipid prodrugs
US11608345B1 (en) 2017-12-19 2023-03-21 Puretech Lyt, Inc. Lipid prodrugs of rapamycin and its analogs and uses thereof
US11304954B2 (en) 2017-12-19 2022-04-19 Puretech Lyt, Inc. Lipid prodrugs of mycophenolic acid and uses thereof
JP7810970B2 (ja) 2020-02-05 2026-02-04 シーポート・セラピューティクス・インコーポレイテッド 神経ステロイドの脂質プロドラッグ

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO1993023021A2 (en) * 1992-05-13 1993-11-25 The Wellcome Foundation Limited Therapeutic combinations

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US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US5047407A (en) 1989-02-08 1991-09-10 Iaf Biochem International, Inc. 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
US5122517A (en) 1988-06-10 1992-06-16 Regents Of The University Of Minnesota Antiviral combination comprising nucleoside analogs
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
US5204466A (en) 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
GB9009861D0 (en) 1990-05-02 1990-06-27 Glaxo Group Ltd Chemical compounds
GB9104740D0 (en) 1991-03-06 1991-04-17 Wellcome Found Antiviral nucleoside combination
ATE131730T1 (de) * 1991-05-16 1996-01-15 Glaxo Group Ltd Nukleosidanalogen enthaltende antiviren- zubereitungen
US5723490A (en) 1992-09-08 1998-03-03 Vertex Pharmaceuticals Incorporated THF-containing sulfonamide inhibitors of aspartyl protease
GB9417249D0 (en) 1994-08-26 1994-10-19 Wellcome Found A novel salt
US5869461A (en) 1995-03-16 1999-02-09 Yale University Reducing toxicity of L-nucleosides with D-nucleosides
KR20000022226A (ko) 1996-06-25 2000-04-25 그레이엄 브레레톤;레슬리 에드워즈 Hiv 치료에 사용하기 위한 vx478, 지도부딘, ftc 및(또는) 3tc를 포함하는 배합물
CA2262765A1 (en) 1996-06-25 1997-12-31 Glaxo Group Limited Combinations comprising vx478, zidovudine and/or 1592u89 for use in the treatment of hiv
DE10226522A1 (de) 2002-06-14 2003-12-24 Degussa Verwendung von Übergangsmetallkomplexen mit stickstoffhaltigen mehrzähnigen Liganden als Bleichkatalysator und Bleichmittelzusammensetzung

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Publication number Priority date Publication date Assignee Title
WO1993023021A2 (en) * 1992-05-13 1993-11-25 The Wellcome Foundation Limited Therapeutic combinations

Also Published As

Publication number Publication date
CZ309097A3 (cs) 1998-05-13
BRPI9607851B8 (pt) 2019-11-05
HK1009401A1 (en) 1999-09-10
LU91171I2 (fr) 2005-07-04
DK0817637T3 (da) 2002-11-11
MY115461A (en) 2003-06-30
EA000626B3 (ru) 2016-04-29
NL300195I2 (nl) 2005-11-01
EE9700240A (et) 1998-04-15
IL117727A0 (en) 1996-07-23
MX9707316A (es) 1997-11-29
ES2179193T3 (es) 2003-01-16
CA2216634A1 (en) 1996-10-03
DE69622386D1 (de) 2002-08-22
HUP9801571A2 (hu) 1999-01-28
JP2954357B2 (ja) 1999-09-27
HU224010B1 (hu) 2005-04-28
SI0817637T1 (en) 2002-10-31
AP652A (en) 1998-06-19
DE69622386T2 (de) 2003-02-13
NZ306419A (en) 2000-01-28
PT817637E (pt) 2002-11-29
NO2005014I2 (no) 2008-02-11
LU91171I9 (cg-RX-API-DMAC7.html) 2018-12-28
PL187085B1 (pl) 2004-05-31
BR9607851B1 (pt) 2009-01-13
RO117995B1 (ro) 2002-12-30
AP9701089A0 (en) 1997-10-31
GEP20022647B (en) 2002-03-25
FR05C0022I2 (cg-RX-API-DMAC7.html) 2005-10-21
ATE220551T1 (de) 2002-08-15
KR19980703420A (ko) 1998-11-05
US6417191B1 (en) 2002-07-09
CA2216634C (en) 2004-07-20
BR9607851A (pt) 1998-07-21
SK129597A3 (en) 1998-07-08
NO313787B1 (no) 2002-12-02
DE122005000029I1 (de) 2005-10-06
IL117727A (en) 1999-11-30
OA10616A (en) 2001-03-15
CZ295940B6 (cs) 2005-12-14
EE04047B1 (et) 2003-06-16
NO2005014I1 (no) 2005-06-06
BRPI9612992B1 (pt) 2020-08-04
EA199700203A1 (ru) 1998-02-26
FR05C0022I1 (cg-RX-API-DMAC7.html) 2005-06-10
CN1103593C (zh) 2003-03-26
HUP9801571A3 (en) 2001-04-28
EA000626B1 (ru) 1999-12-29
DE122005000029I2 (de) 2006-04-27
NL300195I1 (nl) 2005-08-01
TR199701074T1 (xx) 1998-02-21
SK283825B6 (sk) 2004-02-03
WO1996030025A1 (en) 1996-10-03
CN1185110A (zh) 1998-06-17
AU5497296A (en) 1996-10-16
UA60293C2 (uk) 2003-10-15
NO974510D0 (no) 1997-09-29
JPH10511682A (ja) 1998-11-10
NO974510L (no) 1997-09-29
EP0817637B1 (en) 2002-07-17
AU715213B2 (en) 2000-01-20
PL322532A1 (en) 1998-02-02
EP0817637A1 (en) 1998-01-14

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Termination category: Expiration of duration