KR100493980B1 - 면역학적질병의치료를위한치료제로서가용성림포톡신-베타수용체및항-림포톡신수용체및리간드항체 - Google Patents

면역학적질병의치료를위한치료제로서가용성림포톡신-베타수용체및항-림포톡신수용체및리간드항체 Download PDF

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KR100493980B1
KR100493980B1 KR10-1998-0700464A KR19980700464A KR100493980B1 KR 100493980 B1 KR100493980 B1 KR 100493980B1 KR 19980700464 A KR19980700464 A KR 19980700464A KR 100493980 B1 KR100493980 B1 KR 100493980B1
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soluble
cells
receptor
cell
lymphotoxin
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KR19990035805A (ko
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엘. 브라우닝 제프리
디. 벤자민 크리스토퍼
에스. 호크만 폴라
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바이오겐 아이덱 엠에이 인코포레이티드
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y10S930/00—Peptide or protein sequence
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KR10-1998-0700464A 1995-07-21 1996-07-19 면역학적질병의치료를위한치료제로서가용성림포톡신-베타수용체및항-림포톡신수용체및리간드항체 Expired - Fee Related KR100493980B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8/505606 1995-07-21
US08/505,606 US5925351A (en) 1995-07-21 1995-07-21 Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease
US08/505606 1995-07-21

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KR1020047017609A Division KR100557258B1 (ko) 1995-07-21 1996-07-19 면역학적 질병의 치료를 위한 치료제로서 가용성림포톡신-베타 수용체 및 항-림포톡신 수용체 및 리간드항체

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KR19990035805A KR19990035805A (ko) 1999-05-25
KR100493980B1 true KR100493980B1 (ko) 2005-11-11

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KR10-1998-0700464A Expired - Fee Related KR100493980B1 (ko) 1995-07-21 1996-07-19 면역학적질병의치료를위한치료제로서가용성림포톡신-베타수용체및항-림포톡신수용체및리간드항체
KR1020047017609A Expired - Fee Related KR100557258B1 (ko) 1995-07-21 1996-07-19 면역학적 질병의 치료를 위한 치료제로서 가용성림포톡신-베타 수용체 및 항-림포톡신 수용체 및 리간드항체

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US (6) US5925351A (cg-RX-API-DMAC7.html)
EP (2) EP0840616B1 (cg-RX-API-DMAC7.html)
JP (3) JP4174563B2 (cg-RX-API-DMAC7.html)
KR (2) KR100493980B1 (cg-RX-API-DMAC7.html)
CN (3) CN1146441C (cg-RX-API-DMAC7.html)
AT (1) ATE279205T1 (cg-RX-API-DMAC7.html)
AU (1) AU715407B2 (cg-RX-API-DMAC7.html)
BG (1) BG63330B1 (cg-RX-API-DMAC7.html)
BR (1) BR9609716A (cg-RX-API-DMAC7.html)
CA (1) CA2227477A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ298277B6 (cg-RX-API-DMAC7.html)
DE (1) DE69633624T2 (cg-RX-API-DMAC7.html)
DK (1) DK0840616T3 (cg-RX-API-DMAC7.html)
EA (3) EA002966B1 (cg-RX-API-DMAC7.html)
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NZ (2) NZ503818A (cg-RX-API-DMAC7.html)
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PT (1) PT840616E (cg-RX-API-DMAC7.html)
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SI (1) SI0840616T1 (cg-RX-API-DMAC7.html)
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US5925351A (en) * 1995-07-21 1999-07-20 Biogen, Inc. Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease
EP1723967A3 (en) * 1996-10-25 2007-01-10 Biogen Idec MA, Inc. Soluble lymphotoxin-beta receptors, anti-lymphotoxin receptor antibodies and anti-lymphotoxin ligand antibodies as therapeutic agents for the treatment of immunological diseases
US7255854B1 (en) * 1996-10-25 2007-08-14 Biogen, Inc. Use of lymphotoxin-β receptor blocking agents for the treatment of antibody mediated immunological diseases
BR9712670A (pt) * 1996-10-25 1999-10-19 Biogen Inc Receptores para linfotoxina-beta, anticorpos anti-receptor para linfotoxina, e anticorpos antiligante de linfotoxina como agentes terapêuticos para o tratamento de doencas imunológicas
CN1257545A (zh) * 1997-04-18 2000-06-21 拜奥根有限公司 Ⅱ型TGF－β受体/免疫球蛋白恒定区融合蛋白
US7118742B2 (en) * 1997-07-07 2006-10-10 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
CN1287853C (zh) * 1998-01-30 2006-12-06 拜奥根Idec马萨诸塞公司 用淋巴毒素(lt)途径抑制物治疗滤泡性淋巴瘤
US7060667B1 (en) * 1998-01-30 2006-06-13 Biogen Idec Ma, Inc. Treatment of follicular lymphomas using inhibitors of the LT pathway
TR200100974T2 (tr) * 1998-10-09 2001-11-21 Biogen, Inc. Virütik kaynaklı sistematik şok ve solunum zorluğunun,lenfotoksin beta yolunu bloke etmek suretiyle geri çevrilmesi
TR200504220T2 (tr) 1998-12-17 2007-04-24 Biogen Idec Ma Inc. Aktif limfotoksin-beta reseptör imunoglobülin şimeAktif limfotoksin-beta reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştrik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem.ırılması için bir yöntem.
MXPA01013367A (es) * 1999-06-28 2002-07-02 Basf Ag Metodo para la prevencion del crecimiento tumoral.
US6346247B1 (en) 1999-10-28 2002-02-12 Promega Corporation Prevention and treatment of autoimmune disease with luminally administered polyclonal antibodies
NZ525793A (en) * 2000-10-13 2008-04-30 Biogen Idec Inc Humanized anti-LT-beta-R antibodies
SI1724284T1 (sl) * 2000-12-07 2009-12-31 Lilly Co Eli Glp-1 fuzijski proteini
WO2002083162A1 (en) * 2001-04-13 2002-10-24 University Of Chicago Use of a cd8+ t cell inhibitory agent in the presence of a cd4+ t cell inhibitory agent for inhibition of transplant rejection
US7265208B2 (en) * 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
WO2003011322A1 (en) * 2001-08-02 2003-02-13 Genset S.A. Agonists and antagonists of genoxin for use in the treatment of metabolic disorders
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