KR100381120B1 - 경피흡수형튜로부테롤제제및그제조방법 - Google Patents

경피흡수형튜로부테롤제제및그제조방법 Download PDF

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Publication number
KR100381120B1
KR100381120B1 KR10-1998-0702763A KR19980702763A KR100381120B1 KR 100381120 B1 KR100381120 B1 KR 100381120B1 KR 19980702763 A KR19980702763 A KR 19980702763A KR 100381120 B1 KR100381120 B1 KR 100381120B1
Authority
KR
South Korea
Prior art keywords
tulobuterol
adhesive layer
adhesive
particle size
preparation
Prior art date
Application number
KR10-1998-0702763A
Other languages
English (en)
Korean (ko)
Other versions
KR19990064272A (ko
Inventor
다케아키 나카가와
요시히사 나카노
사부로 오츠카
Original Assignee
닛토덴코 가부시키가이샤
호쿠리쿠 세이야쿠 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 닛토덴코 가부시키가이샤, 호쿠리쿠 세이야쿠 가부시키가이샤 filed Critical 닛토덴코 가부시키가이샤
Publication of KR19990064272A publication Critical patent/KR19990064272A/ko
Application granted granted Critical
Publication of KR100381120B1 publication Critical patent/KR100381120B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Botany (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR10-1998-0702763A 1995-10-17 1996-08-28 경피흡수형튜로부테롤제제및그제조방법 KR100381120B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26846595 1995-10-17
JP95-268465 1995-10-17

Publications (2)

Publication Number Publication Date
KR19990064272A KR19990064272A (ko) 1999-07-26
KR100381120B1 true KR100381120B1 (ko) 2003-08-30

Family

ID=17458884

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-1998-0702763A KR100381120B1 (ko) 1995-10-17 1996-08-28 경피흡수형튜로부테롤제제및그제조방법

Country Status (9)

Country Link
JP (1) JP3260765B2 (fr)
KR (1) KR100381120B1 (fr)
CN (1) CN1104893C (fr)
AU (1) AU707661B2 (fr)
BR (1) BR9610943A (fr)
HK (1) HK1017997A1 (fr)
HU (1) HUP0000403A3 (fr)
PL (1) PL185797B1 (fr)
WO (1) WO1997014411A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101365321B1 (ko) 2012-05-22 2014-02-20 제일약품주식회사 매트릭스내 비스테로이드성 소염진통제의 농도구배를 이용하여 경피투과도를 향상시킨 패취제

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004284953A (ja) * 2000-07-13 2004-10-14 Hisamitsu Pharmaceut Co Inc 貼付剤
KR100535302B1 (ko) * 2002-02-01 2005-12-08 주식회사 태평양 툴로부테롤 함유 경피흡수형 제제
JP5512910B2 (ja) * 2003-04-10 2014-06-04 テイカ製薬株式会社 ツロブテロール含有経皮吸収製剤およびこれを使用する貼付剤
WO2004112770A1 (fr) 2003-06-20 2004-12-29 Teikoku Seiyaku Co., Ltd. Timbre adhesif contenant du tulobuterol
CN1297257C (zh) * 2004-01-02 2007-01-31 上海现代药物制剂工程研究中心有限公司 含有妥洛特罗的压敏胶，透皮贴剂及制备方法和应用
WO2005067910A1 (fr) 2004-01-20 2005-07-28 Saitama Daiichi Pharmaceutical Co., Ltd. Mouche adhesive de tulobuterol
JP4481732B2 (ja) * 2004-06-08 2010-06-16 日東電工株式会社 結晶混在型経皮吸収製剤およびその製造方法
JP2006248996A (ja) * 2005-03-10 2006-09-21 Nitto Denko Corp 経皮吸収型貼付剤
JP4722628B2 (ja) 2005-09-05 2011-07-13 日東電工株式会社 経皮吸収型製剤
JP5243254B2 (ja) * 2006-10-11 2013-07-24 久光製薬株式会社 結晶含有貼付剤
WO2011059037A1 (fr) * 2009-11-12 2011-05-19 学校法人日本大学 Composition phatmaceutique pour usage externe/
CN105439875B (zh) * 2016-01-29 2017-12-29 山东达因海洋生物制药股份有限公司 一种化合物妥洛特罗的合成方法
CN108236606B (zh) * 2016-12-23 2022-01-11 中国医学科学院药物研究所 经皮吸收的妥洛特罗控释贴剂及其制备方法
CN108853065B (zh) * 2018-07-19 2019-06-28 山东大学 一种妥洛特罗透皮贴剂及其制备方法
CN112707829B (zh) * 2020-12-25 2023-07-21 山东达因海洋生物制药股份有限公司 一种妥洛特罗晶型及制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60185713A (ja) * 1984-03-05 1985-09-21 Nitto Electric Ind Co Ltd 経皮吸収性製剤及びその製法
JPH05194202A (ja) * 1990-01-26 1993-08-03 Lts Lohmann Therapie Syst Gmbh & Co Kg 活性物質としてチュロブテロールを有する医療システム

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0156080B2 (fr) * 1984-03-05 1993-10-20 Nitto Denko Corporation Préparation pharmaceutique adhésive du type à absorption percutanée
JPS6310716A (ja) * 1986-07-02 1988-01-18 Teijin Ltd β−刺激薬外用剤
IT1251469B (it) * 1991-07-15 1995-05-15 Zambon Spa Sistema terapeutico transdermale per la somministrazione di farmaci ad attivita' broncodilatante.
JP2753800B2 (ja) * 1994-04-14 1998-05-20 日東電工株式会社 経皮吸収型製剤
JPH0985854A (ja) * 1995-09-26 1997-03-31 Isowa Corp 段ボールシート製函機のスロッタ角切り装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60185713A (ja) * 1984-03-05 1985-09-21 Nitto Electric Ind Co Ltd 経皮吸収性製剤及びその製法
JPH05194202A (ja) * 1990-01-26 1993-08-03 Lts Lohmann Therapie Syst Gmbh & Co Kg 活性物質としてチュロブテロールを有する医療システム

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101365321B1 (ko) 2012-05-22 2014-02-20 제일약품주식회사 매트릭스내 비스테로이드성 소염진통제의 농도구배를 이용하여 경피투과도를 향상시킨 패취제

Also Published As

Publication number Publication date
PL326249A1 (en) 1998-08-31
CN1204260A (zh) 1999-01-06
KR19990064272A (ko) 1999-07-26
HK1017997A1 (en) 1999-12-10
CN1104893C (zh) 2003-04-09
AU6837496A (en) 1997-05-07
PL185797B1 (pl) 2003-07-31
BR9610943A (pt) 1999-12-21
HUP0000403A3 (en) 2000-10-30
AU707661B2 (en) 1999-07-15
HUP0000403A2 (hu) 2000-08-28
WO1997014411A1 (fr) 1997-04-24
JP3260765B2 (ja) 2002-02-25

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