BR9610943A - Preparação de tulobuterol do tipo de absorção percutânea e processo para a produção da mesma. - Google Patents
Preparação de tulobuterol do tipo de absorção percutânea e processo para a produção da mesma.Info
- Publication number
- BR9610943A BR9610943A BR9610943-2A BR9610943A BR9610943A BR 9610943 A BR9610943 A BR 9610943A BR 9610943 A BR9610943 A BR 9610943A BR 9610943 A BR9610943 A BR 9610943A
- Authority
- BR
- Brazil
- Prior art keywords
- tulobuterol
- preparation
- percutaneous absorption
- absorption type
- production
- Prior art date
Links
- YREYLAVBNPACJM-UHFFFAOYSA-N 2-(tert-butylamino)-1-(2-chlorophenyl)ethanol Chemical compound CC(C)(C)NCC(O)C1=CC=CC=C1Cl YREYLAVBNPACJM-UHFFFAOYSA-N 0.000 title abstract 11
- 229960000859 tulobuterol Drugs 0.000 title abstract 11
- 238000002360 preparation method Methods 0.000 title abstract 7
- 238000010521 absorption reaction Methods 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 239000012790 adhesive layer Substances 0.000 abstract 4
- 239000000853 adhesive Substances 0.000 abstract 3
- 230000001070 adhesive effect Effects 0.000 abstract 3
- 229920003051 synthetic elastomer Polymers 0.000 abstract 3
- 239000005061 synthetic rubber Substances 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 230000000857 drug effect Effects 0.000 abstract 1
- 238000001953 recrystallisation Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Botany (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP26846595 | 1995-10-17 | ||
PCT/JP1996/002422 WO1997014411A1 (fr) | 1995-10-17 | 1996-08-28 | Preparation a base de tulobuterol administrable par voie transcutanee et son procede de production |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9610943A true BR9610943A (pt) | 1999-12-21 |
Family
ID=17458884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9610943-2A BR9610943A (pt) | 1995-10-17 | 1996-08-28 | Preparação de tulobuterol do tipo de absorção percutânea e processo para a produção da mesma. |
Country Status (9)
Country | Link |
---|---|
JP (1) | JP3260765B2 (fr) |
KR (1) | KR100381120B1 (fr) |
CN (1) | CN1104893C (fr) |
AU (1) | AU707661B2 (fr) |
BR (1) | BR9610943A (fr) |
HK (1) | HK1017997A1 (fr) |
HU (1) | HUP0000403A3 (fr) |
PL (1) | PL185797B1 (fr) |
WO (1) | WO1997014411A1 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004284953A (ja) * | 2000-07-13 | 2004-10-14 | Hisamitsu Pharmaceut Co Inc | 貼付剤 |
KR100535302B1 (ko) * | 2002-02-01 | 2005-12-08 | 주식회사 태평양 | 툴로부테롤 함유 경피흡수형 제제 |
JP5512910B2 (ja) * | 2003-04-10 | 2014-06-04 | テイカ製薬株式会社 | ツロブテロール含有経皮吸収製剤およびこれを使用する貼付剤 |
WO2004112770A1 (fr) | 2003-06-20 | 2004-12-29 | Teikoku Seiyaku Co., Ltd. | Timbre adhesif contenant du tulobuterol |
CN1297257C (zh) * | 2004-01-02 | 2007-01-31 | 上海现代药物制剂工程研究中心有限公司 | 含有妥洛特罗的压敏胶,透皮贴剂及制备方法和应用 |
WO2005067910A1 (fr) | 2004-01-20 | 2005-07-28 | Saitama Daiichi Pharmaceutical Co., Ltd. | Mouche adhesive de tulobuterol |
JP4481732B2 (ja) * | 2004-06-08 | 2010-06-16 | 日東電工株式会社 | 結晶混在型経皮吸収製剤およびその製造方法 |
JP2006248996A (ja) * | 2005-03-10 | 2006-09-21 | Nitto Denko Corp | 経皮吸収型貼付剤 |
JP4722628B2 (ja) | 2005-09-05 | 2011-07-13 | 日東電工株式会社 | 経皮吸収型製剤 |
JP5243254B2 (ja) * | 2006-10-11 | 2013-07-24 | 久光製薬株式会社 | 結晶含有貼付剤 |
WO2011059037A1 (fr) * | 2009-11-12 | 2011-05-19 | 学校法人日本大学 | Composition phatmaceutique pour usage externe/ |
KR101365321B1 (ko) | 2012-05-22 | 2014-02-20 | 제일약품주식회사 | 매트릭스내 비스테로이드성 소염진통제의 농도구배를 이용하여 경피투과도를 향상시킨 패취제 |
CN105439875B (zh) * | 2016-01-29 | 2017-12-29 | 山东达因海洋生物制药股份有限公司 | 一种化合物妥洛特罗的合成方法 |
CN108236606B (zh) * | 2016-12-23 | 2022-01-11 | 中国医学科学院药物研究所 | 经皮吸收的妥洛特罗控释贴剂及其制备方法 |
CN108853065B (zh) * | 2018-07-19 | 2019-06-28 | 山东大学 | 一种妥洛特罗透皮贴剂及其制备方法 |
CN112707829B (zh) * | 2020-12-25 | 2023-07-21 | 山东达因海洋生物制药股份有限公司 | 一种妥洛特罗晶型及制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0156080B2 (fr) * | 1984-03-05 | 1993-10-20 | Nitto Denko Corporation | Préparation pharmaceutique adhésive du type à absorption percutanée |
JPS60185713A (ja) * | 1984-03-05 | 1985-09-21 | Nitto Electric Ind Co Ltd | 経皮吸収性製剤及びその製法 |
JPS6310716A (ja) * | 1986-07-02 | 1988-01-18 | Teijin Ltd | β−刺激薬外用剤 |
DE4002281A1 (de) * | 1990-01-26 | 1991-08-01 | Lohmann Therapie Syst Lts | Transdermales therapeutisches system mit dem wirkstoff tulobuterol |
IT1251469B (it) * | 1991-07-15 | 1995-05-15 | Zambon Spa | Sistema terapeutico transdermale per la somministrazione di farmaci ad attivita' broncodilatante. |
JP2753800B2 (ja) * | 1994-04-14 | 1998-05-20 | 日東電工株式会社 | 経皮吸収型製剤 |
JPH0985854A (ja) * | 1995-09-26 | 1997-03-31 | Isowa Corp | 段ボールシート製函機のスロッタ角切り装置 |
-
1996
- 1996-08-28 AU AU68374/96A patent/AU707661B2/en not_active Ceased
- 1996-08-28 PL PL96326249A patent/PL185797B1/pl not_active IP Right Cessation
- 1996-08-28 HU HU0000403A patent/HUP0000403A3/hu unknown
- 1996-08-28 KR KR10-1998-0702763A patent/KR100381120B1/ko active IP Right Grant
- 1996-08-28 WO PCT/JP1996/002422 patent/WO1997014411A1/fr active IP Right Grant
- 1996-08-28 JP JP51567897A patent/JP3260765B2/ja not_active Expired - Lifetime
- 1996-08-28 CN CN96198929A patent/CN1104893C/zh not_active Expired - Lifetime
- 1996-08-28 BR BR9610943-2A patent/BR9610943A/pt not_active Application Discontinuation
-
1999
- 1999-05-27 HK HK99102386A patent/HK1017997A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PL326249A1 (en) | 1998-08-31 |
CN1204260A (zh) | 1999-01-06 |
KR19990064272A (ko) | 1999-07-26 |
HK1017997A1 (en) | 1999-12-10 |
CN1104893C (zh) | 2003-04-09 |
AU6837496A (en) | 1997-05-07 |
PL185797B1 (pl) | 2003-07-31 |
HUP0000403A3 (en) | 2000-10-30 |
KR100381120B1 (ko) | 2003-08-30 |
AU707661B2 (en) | 1999-07-15 |
HUP0000403A2 (hu) | 2000-08-28 |
WO1997014411A1 (fr) | 1997-04-24 |
JP3260765B2 (ja) | 2002-02-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Free format text: NITTO DENKO CORPORATION (JP), ABBOTT JAPAN CO., LTD (JP) |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE PATENTE COM BASE NOS ARTIGOS 8 E 13 DA LPI NO9.279 DE 14/05/1996 |