KR100331978B1 - 금속착체를포함하는의약조성물 - Google Patents

금속착체를포함하는의약조성물 Download PDF

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Publication number
KR100331978B1
KR100331978B1 KR1019960700936A KR19960700936A KR100331978B1 KR 100331978 B1 KR100331978 B1 KR 100331978B1 KR 1019960700936 A KR1019960700936 A KR 1019960700936A KR 19960700936 A KR19960700936 A KR 19960700936A KR 100331978 B1 KR100331978 B1 KR 100331978B1
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KR
South Korea
Prior art keywords
complex
disease
formula
involved
reducing
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Expired - Fee Related
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KR1019960700936A
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English (en)
Korean (ko)
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KR960703609A (ko
Inventor
제프리 아브람스 마이클
폴 프릭커 사이먼
앤터니 머러 배리
존 본 오인
Original Assignee
아노메드 인코포레이티드
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Publication of KR960703609A publication Critical patent/KR960703609A/ko
Application granted granted Critical
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Anticipated expiration legal-status Critical
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019960700936A 1993-08-25 1994-08-19 금속착체를포함하는의약조성물 Expired - Fee Related KR100331978B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939317686A GB9317686D0 (en) 1993-08-25 1993-08-25 Pharmaceutical compositions
GB9317686.5 1993-08-25
PCT/GB1994/001817 WO1995005814A1 (en) 1993-08-25 1994-08-19 Pharmaceutical compositions comprising metal complexes

Publications (2)

Publication Number Publication Date
KR960703609A KR960703609A (ko) 1996-08-31
KR100331978B1 true KR100331978B1 (ko) 2002-09-26

Family

ID=10741021

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019960700936A Expired - Fee Related KR100331978B1 (ko) 1993-08-25 1994-08-19 금속착체를포함하는의약조성물

Country Status (14)

Country Link
US (1) US5824673A (enExample)
EP (1) EP0714294A1 (enExample)
JP (1) JPH09501927A (enExample)
KR (1) KR100331978B1 (enExample)
AU (1) AU698785B2 (enExample)
CA (1) CA2170253A1 (enExample)
FI (1) FI960849A7 (enExample)
GB (1) GB9317686D0 (enExample)
HU (1) HUT74947A (enExample)
NO (1) NO960754L (enExample)
NZ (1) NZ269596A (enExample)
TW (1) TW282401B (enExample)
WO (1) WO1995005814A1 (enExample)
ZA (1) ZA946262B (enExample)

Families Citing this family (34)

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US6417182B1 (en) * 1993-08-25 2002-07-09 Anormed Inc. Pharmaceutical compositions comprising metal complexes
US6265441B1 (en) * 1994-05-11 2001-07-24 Jes Olesen Use of no scavengers, inhibitors of antagonists in the treatment of migraine
US6245758B1 (en) 1994-05-13 2001-06-12 Michael K. Stern Methods of use for peroxynitrite decomposition catalysts, pharmaceutical compositions therefor
PL317192A1 (en) * 1994-05-13 1997-03-17 Monsanto Co Methods of using pernitrite decomposition catalyst and their pharmaceutic compositions
US6743771B2 (en) * 1995-12-29 2004-06-01 Novactyl, Inc. Methods and compositions for controlling protein assembly or aggregation
US20030013772A1 (en) * 2000-02-23 2003-01-16 Murphy Michael A. Composition, synthesis and therapeutic applications of polyamines
DE19860289C2 (de) * 1998-12-21 2003-11-13 Schering Ag Neue Chelatoren sowie deren Tricarbonyl-Komplexe mit Technetium und Rhenium
MXPA01009410A (es) * 1999-03-19 2003-06-06 Anormed Inc Composiciones farmaceuticas que comprenden complejos de metal.
AU6928700A (en) * 1999-08-25 2001-03-19 Clarity Biosciences, Inc. Identifying organisms by detecting intronic nucleic acid or encoded proteins
US7335383B2 (en) * 2001-01-16 2008-02-26 The Regents Of The University Of Michigan Generation of nitric oxide in vivo from nitrite, nitrate or nitrosothiols endogenous in blood
US7128904B2 (en) * 2001-01-16 2006-10-31 The Regents Of The University Of Michigan Material containing metal ion ligand complex producing nitric oxide in contact with blood
WO2002077160A2 (en) * 2001-03-01 2002-10-03 Clarity Biosciences, Inc. Methods of making and uses of compositions that modulate intronic region-encoded protein function
GB0111872D0 (en) 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
US20080026984A1 (en) * 2002-02-04 2008-01-31 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
CA2475209A1 (en) 2002-02-04 2003-08-14 Alfama - Investigacao E Desenvolvimento De Produtos Farmaceuticos Lda. Use of co-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases
US7968605B2 (en) * 2002-02-04 2011-06-28 ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
GB2395432B (en) * 2002-11-20 2005-09-14 Northwick Park Inst For Medica Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
US20070207217A1 (en) * 2003-02-03 2007-09-06 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Method for treating a mammal by administration of a compound having the ability to release CO
CN1318430C (zh) * 2003-04-24 2007-05-30 钟文远 一类稀土配合物及其制备方法和在制备治疗肿瘤药物中的应用
KR20060125790A (ko) * 2003-11-07 2006-12-06 가부시키가이샤 시테크 뇌경색의 예방 및/또는 치료를 위한 의약
US20060008529A1 (en) * 2004-07-12 2006-01-12 Meyerhoff Mark E Use of additive sites to control nitric oxide release from nitric oxide donors contained within polymers
US20060039950A1 (en) * 2004-08-23 2006-02-23 Zhengrong Zhou Multi-functional biocompatible coatings for intravascular devices
US20080241208A1 (en) * 2005-06-30 2008-10-02 Charles Shanley Methods, Compositions and Devices For Promoting Anglogenesis
CN101378792A (zh) * 2005-12-02 2009-03-04 密执安大学评议会 聚合物组合物、涂层和装置及其制备和使用方法
GB0601394D0 (en) 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
US20080119002A1 (en) * 2006-11-17 2008-05-22 Charles Grosjean Substrate contact for a MEMS device
US8597563B2 (en) 2008-07-11 2013-12-03 Rohm And Haas Company Recycled thermoplastic composition comprising waste thermoset material and methods of making
DE102010014412A1 (de) 2010-04-08 2012-04-19 Friedrich-Schiller-Universität Jena Verwendung von zweikernigen Eisenkomplexen mit schwefelhaltigen Liganden als pharmakologische Wirkstoffe
DE102010014411A1 (de) 2010-04-08 2011-10-13 Friedrich-Schiller-Universität Jena Kohlenmonoxid und Eisen freisetzende Moleküle, deren Verwendung und Verfahren zu deren Herstellung
WO2012138988A2 (en) * 2011-04-07 2012-10-11 The Research Foundation Of The City University Of New York Organometallic anti-cancer complexes
PT2699242T (pt) 2011-04-19 2018-01-22 Alfama Inc Moléculas de libertação de monóxido de carbono e utilizações das mesmas
EP2734235B1 (en) 2011-07-21 2017-03-22 Alfama, Inc. Ruthenium carbon monoxide releasing molecules and uses thereof
DE102012004132A1 (de) 2012-02-29 2013-08-29 Friedrich-Schiller-Universität Jena Kohlenstoffmonoxid freisetzende Materialien und deren Verwendung
DE102014008537A1 (de) 2014-06-04 2015-12-17 Friedrich-Schiller-Universität Jena Wasserlösliche manganbasierte Kohlenstoffmonoxid freisetzende Moleküle, deren Verwendung und Verfahren zu deren Herstellung

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000804A1 (fr) * 1984-07-24 1986-02-13 Byk Gulden Lomberg Chemische Fabrik Gesellschaft M Compositions de ruthenium a effet inhibiteur de tumeurs

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1482811A (fr) * 1960-01-26 1967-06-02 Australian Nat University Pers Nouveaux complexes métallifères d'agents de coordination homogènes, et leur procédé de préparation
WO1986000905A1 (fr) * 1984-07-24 1986-02-13 Byk Gulden Lomberg Chemische Fabrik Gesellschaft M Compositions de ruthenium a effet inhibiteur de tumeurs
US5157032A (en) * 1985-01-18 1992-10-20 The Trustees Of Columbia University In The City Of New York Mixed ligand complexes and uses thereof as binding agents and probes to DNA
IT1230145B (it) * 1989-05-05 1991-10-14 Boehringer Biochemia Srl Complessi di rutenio (iii) come agenti antineoplastici.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000804A1 (fr) * 1984-07-24 1986-02-13 Byk Gulden Lomberg Chemische Fabrik Gesellschaft M Compositions de ruthenium a effet inhibiteur de tumeurs

Also Published As

Publication number Publication date
US5824673A (en) 1998-10-20
NO960754D0 (no) 1996-02-23
FI960849L (fi) 1996-02-23
AU698785B2 (en) 1998-11-05
WO1995005814A1 (en) 1995-03-02
HUT74947A (en) 1997-03-28
GB9317686D0 (en) 1993-10-13
NO960754L (no) 1996-04-23
TW282401B (enExample) 1996-08-01
FI960849A0 (fi) 1996-02-23
FI960849A7 (fi) 1996-02-23
JPH09501927A (ja) 1997-02-25
HU9600441D0 (en) 1996-04-29
ZA946262B (en) 1995-03-20
NZ269596A (en) 1997-05-26
KR960703609A (ko) 1996-08-31
EP0714294A1 (en) 1996-06-05
CA2170253A1 (en) 1995-03-02
AU7390794A (en) 1995-03-21

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