KR100270410B1 - 타이로시네이즈 활성 저해능을 갖는 신규 1,3-디페닐프로판 유도체 및 그의 제조방법 - Google Patents

타이로시네이즈 활성 저해능을 갖는 신규 1,3-디페닐프로판 유도체 및 그의 제조방법 Download PDF

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Publication number
KR100270410B1
KR100270410B1 KR1019970077618A KR19970077618A KR100270410B1 KR 100270410 B1 KR100270410 B1 KR 100270410B1 KR 1019970077618 A KR1019970077618 A KR 1019970077618A KR 19970077618 A KR19970077618 A KR 19970077618A KR 100270410 B1 KR100270410 B1 KR 100270410B1
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South Korea
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compound
formula
hydrogen
phenyl
alkyl
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Expired - Fee Related
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KR1019970077618A
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English (en)
Korean (ko)
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KR19980079558A (ko
Inventor
이영호
김경애
이현호
최종권
이상화
Original Assignee
성재갑
주식회사엘지화학
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Priority to KR1019970077618A priority Critical patent/KR100270410B1/ko
Publication of KR19980079558A publication Critical patent/KR19980079558A/ko
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Publication of KR100270410B1 publication Critical patent/KR100270410B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/15—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/17—Saturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C49/172—Saturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
KR1019970077618A 1997-03-06 1997-12-30 타이로시네이즈 활성 저해능을 갖는 신규 1,3-디페닐프로판 유도체 및 그의 제조방법 Expired - Fee Related KR100270410B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019970077618A KR100270410B1 (ko) 1997-03-06 1997-12-30 타이로시네이즈 활성 저해능을 갖는 신규 1,3-디페닐프로판 유도체 및 그의 제조방법

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR1019970007452 1997-03-06
KR19970007452 1997-03-06
KR101997007452 1997-03-06
KR1019970077618A KR100270410B1 (ko) 1997-03-06 1997-12-30 타이로시네이즈 활성 저해능을 갖는 신규 1,3-디페닐프로판 유도체 및 그의 제조방법

Publications (2)

Publication Number Publication Date
KR19980079558A KR19980079558A (ko) 1998-11-25
KR100270410B1 true KR100270410B1 (ko) 2000-11-01

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KR1019970077618A Expired - Fee Related KR100270410B1 (ko) 1997-03-06 1997-12-30 타이로시네이즈 활성 저해능을 갖는 신규 1,3-디페닐프로판 유도체 및 그의 제조방법

Country Status (11)

Country Link
US (1) US6093836A (enExample)
EP (1) EP0909267B1 (enExample)
JP (1) JP3012005B2 (enExample)
KR (1) KR100270410B1 (enExample)
CN (1) CN1102139C (enExample)
AT (1) ATE209172T1 (enExample)
AU (1) AU6122698A (enExample)
DE (1) DE69803264T2 (enExample)
IN (1) IN188006B (enExample)
TW (1) TW513391B (enExample)
WO (1) WO1998039279A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA06013705A (es) 2004-05-28 2007-02-13 Unigen Pharmaceuticals Inc Diarilalcanos como potentes inhibidores de enzimas binucleares.
EP3542780B1 (en) * 2008-07-21 2022-01-19 Unigen, Inc. Series of skin-whitening (lightening) compounds
KR101976642B1 (ko) 2011-03-24 2019-05-09 유니젠, 인크. 디아릴프로판의 제조를 위한 화합물 및 방법
CN103922979B (zh) * 2013-01-11 2016-05-25 卫生福利部国家中医药研究所 皮肤美白用化合物及皮肤用组成物
CN107827726B (zh) * 2017-11-28 2020-09-15 辽宁中医药大学 马齿苋中化合物Oleracone E及其提取分离方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU163394B (enExample) * 1971-12-20 1973-08-28
HU188239B (en) * 1982-12-28 1986-03-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for the production of new resorcinol-derivatives and of therapeutic preparations containing them
KR890700117A (ko) * 1986-12-12 1989-03-02 쓰무라 아끼라 유효성분으로서 칼콘 유도체를 함유하는 항 궤양제 및 신규의 칼콘 유도체
AU6727290A (en) * 1989-10-19 1991-05-16 Schering Corporation Lipoxygenase inhibitors
HK1003994A1 (en) * 1990-04-18 1998-11-13 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. Improved process for the preparation of ketone compounds
EP0674530B1 (en) * 1992-12-21 2004-09-01 Mallinckrodt Inc. Radiolabeled polyhydric phenol compounds
EP0721930A4 (en) * 1994-07-27 1997-07-16 Mitsubishi Chem Corp BENZOETHYLENE DERIVATIVE

Also Published As

Publication number Publication date
DE69803264T2 (de) 2002-08-08
ATE209172T1 (de) 2001-12-15
TW513391B (en) 2002-12-11
US6093836A (en) 2000-07-25
AU6122698A (en) 1998-09-22
KR19980079558A (ko) 1998-11-25
IN188006B (enExample) 2002-08-03
JP3012005B2 (ja) 2000-02-21
EP0909267A1 (en) 1999-04-21
DE69803264D1 (de) 2002-02-21
WO1998039279A1 (en) 1998-09-11
JPH11509239A (ja) 1999-08-17
EP0909267B1 (en) 2001-11-21
CN1102139C (zh) 2003-02-26
CN1217709A (zh) 1999-05-26

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