ATE209172T1 - 1,3-diphenylpropanderivate mit hemmender aktivität gegen tyrosinase und verfahren zu deren herstellung - Google Patents
1,3-diphenylpropanderivate mit hemmender aktivität gegen tyrosinase und verfahren zu deren herstellungInfo
- Publication number
- ATE209172T1 ATE209172T1 AT98905856T AT98905856T ATE209172T1 AT E209172 T1 ATE209172 T1 AT E209172T1 AT 98905856 T AT98905856 T AT 98905856T AT 98905856 T AT98905856 T AT 98905856T AT E209172 T1 ATE209172 T1 AT E209172T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- pct
- activity against
- production
- against tyrosinase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
- C07C39/15—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/17—Saturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups
- C07C49/172—Saturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR19970007452 | 1997-03-06 | ||
PCT/KR1998/000039 WO1998039279A1 (en) | 1997-03-06 | 1998-03-02 | Novel 1,3-diphenylpropane derivatives having inhibitory activity against tyrosinase and process for preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE209172T1 true ATE209172T1 (de) | 2001-12-15 |
Family
ID=19498891
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98905856T ATE209172T1 (de) | 1997-03-06 | 1998-03-02 | 1,3-diphenylpropanderivate mit hemmender aktivität gegen tyrosinase und verfahren zu deren herstellung |
Country Status (11)
Country | Link |
---|---|
US (1) | US6093836A (de) |
EP (1) | EP0909267B1 (de) |
JP (1) | JP3012005B2 (de) |
KR (1) | KR100270410B1 (de) |
CN (1) | CN1102139C (de) |
AT (1) | ATE209172T1 (de) |
AU (1) | AU6122698A (de) |
DE (1) | DE69803264T2 (de) |
IN (1) | IN188006B (de) |
TW (1) | TW513391B (de) |
WO (1) | WO1998039279A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL1748767T3 (pl) | 2004-05-28 | 2012-08-31 | Unigen Inc | 1-(3-metylo-2,4-dimetoksyfenylo)-3-(2',4'-dihydroksyfenylo)-propan jako silny inhibitor tyrozynazy |
EP4046619A1 (de) | 2008-07-21 | 2022-08-24 | Unigen, Inc. | Serie von hautaufhellenden (bleichenden) verbindungen |
US8586799B2 (en) | 2011-03-24 | 2013-11-19 | Unigen, Inc. | Compounds and methods for preparation of diarylpropanes |
CN103922979B (zh) * | 2013-01-11 | 2016-05-25 | 卫生福利部国家中医药研究所 | 皮肤美白用化合物及皮肤用组成物 |
CN107827726B (zh) * | 2017-11-28 | 2020-09-15 | 辽宁中医药大学 | 马齿苋中化合物Oleracone E及其提取分离方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU163394B (de) * | 1971-12-20 | 1973-08-28 | ||
HU188239B (en) * | 1982-12-28 | 1986-03-28 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for the production of new resorcinol-derivatives and of therapeutic preparations containing them |
KR890700117A (ko) * | 1986-12-12 | 1989-03-02 | 쓰무라 아끼라 | 유효성분으로서 칼콘 유도체를 함유하는 항 궤양제 및 신규의 칼콘 유도체 |
JPH05503923A (ja) * | 1989-10-19 | 1993-06-24 | シェリング・コーポレーション | リポキシゲナーゼインヒビター |
WO1991016293A1 (en) * | 1990-04-18 | 1991-10-31 | CHINOIN GYÓGYSZER ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT Tó utca 1-5 | Improved process for the preparation of ketone compounds |
WO1994014477A1 (en) * | 1992-12-21 | 1994-07-07 | Mallinckrodt Medical, Inc. | Polyhydric phenol compounds |
EP0721930A4 (de) * | 1994-07-27 | 1997-07-16 | Mitsubishi Chem Corp | Benzoethylenderivat |
-
1997
- 1997-12-30 KR KR1019970077618A patent/KR100270410B1/ko not_active IP Right Cessation
-
1998
- 1998-03-02 JP JP10538390A patent/JP3012005B2/ja not_active Expired - Fee Related
- 1998-03-02 WO PCT/KR1998/000039 patent/WO1998039279A1/en active IP Right Grant
- 1998-03-02 US US09/180,352 patent/US6093836A/en not_active Expired - Fee Related
- 1998-03-02 EP EP98905856A patent/EP0909267B1/de not_active Expired - Lifetime
- 1998-03-02 CN CN98800210A patent/CN1102139C/zh not_active Expired - Fee Related
- 1998-03-02 DE DE69803264T patent/DE69803264T2/de not_active Expired - Fee Related
- 1998-03-02 AU AU61226/98A patent/AU6122698A/en not_active Abandoned
- 1998-03-02 AT AT98905856T patent/ATE209172T1/de not_active IP Right Cessation
- 1998-03-02 IN IN535DE1998 patent/IN188006B/en unknown
- 1998-03-05 TW TW087103180A patent/TW513391B/zh active
Also Published As
Publication number | Publication date |
---|---|
CN1102139C (zh) | 2003-02-26 |
EP0909267A1 (de) | 1999-04-21 |
TW513391B (en) | 2002-12-11 |
DE69803264T2 (de) | 2002-08-08 |
AU6122698A (en) | 1998-09-22 |
WO1998039279A1 (en) | 1998-09-11 |
KR19980079558A (ko) | 1998-11-25 |
JPH11509239A (ja) | 1999-08-17 |
CN1217709A (zh) | 1999-05-26 |
KR100270410B1 (ko) | 2000-11-01 |
DE69803264D1 (de) | 2002-02-21 |
US6093836A (en) | 2000-07-25 |
EP0909267B1 (de) | 2001-11-21 |
JP3012005B2 (ja) | 2000-02-21 |
IN188006B (de) | 2002-08-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1109441T1 (el) | Ενδιαμεσα προϊοντα για την παραγωγη διοξανιου-2-αλκυλκαρβαμικου | |
NZ536734A (en) | Spiroindolinepiperidine derivatives | |
TW200642683A (en) | Heterocyclic compound | |
GEP20115347B (en) | Heterocyclocarboxamide derivatives | |
CY1110399T1 (el) | Ρυθμιστες της τετραϋδροπυρανυλο κυκλοπεντυλο τετραϋδροπυριδοπυριδινης για την ενεργοτητα των υποδοχεων των χημειοκινων | |
MXPA06012595A (es) | Analogos de amino-tetrazoles y metodos de uso. | |
DE60019904D1 (de) | Verwendung von sulfamat derivaten zur behandlung von impulsiven störungen | |
MY142807A (en) | Benzimidazole derivative and use thereof. | |
MX2007000505A (es) | Derivados de oxindol sustituidos y medicamentos que contienen los mismos. | |
CO5580768A2 (es) | Derivados de 4,5-diariltiazol como ligandos cb-1 | |
EA200601830A1 (ru) | Ортозамещённые арильные или гетероарильные амидные соединения | |
TR200100439T2 (tr) | 1H-İmidazopiridin türevleri | |
NO20044807L (no) | Heratitt C virus inhibitorer | |
NO20062267L (no) | Hepatitt C virus inhibitorer | |
UA27238C2 (uk) | Індолінові похідні, а також їх фармацевтично прийнятні солі, що є антагоністами вазопресинових v1-рецепторів, спосіб їх одержання, проміжні продукти і фармацевтична композиція | |
WO1999033858A3 (en) | Estrone sulfamate inhibitors of estrone sulfatase, and associated pharmaceutical compositions and methods of use | |
ES2191412T3 (es) | Derivados de aminoacidos que contienen fluor. | |
DE69012351D1 (de) | Neue Zwischenprodukte, ihre Herstellung und Verwendung. | |
RS51190B (sr) | Aminoacilni derivati kao prolekovi i lekovi za lečenje tromboembolijskih bolesti | |
GEP20074256B (en) | Novel benzothiadiazine, process for their preparation and pharmaceutical compositions containing | |
ATE209172T1 (de) | 1,3-diphenylpropanderivate mit hemmender aktivität gegen tyrosinase und verfahren zu deren herstellung | |
ATE414692T1 (de) | Pyridinketone mit herbizideffekt | |
ATE454383T1 (de) | Neue verbindungen, deren verwendung und herstellung | |
TW200735867A (en) | Medicine comprising substituted urea derivative | |
EA200300458A1 (ru) | Новые соединения аминотриазолона, способ их получения и фармацевтические композиции, содержащие их |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |