KR100243440B1 - 세코-누클레오시드의 리포누클레오티드, 이들의 제조방법 및 항바이러스제로서 이들을 사용하는 방법 - Google Patents

세코-누클레오시드의 리포누클레오티드, 이들의 제조방법 및 항바이러스제로서 이들을 사용하는 방법 Download PDF

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Publication number
KR100243440B1
KR100243440B1 KR1019950700463A KR19950700463A KR100243440B1 KR 100243440 B1 KR100243440 B1 KR 100243440B1 KR 1019950700463 A KR1019950700463 A KR 1019950700463A KR 19950700463 A KR19950700463 A KR 19950700463A KR 100243440 B1 KR100243440 B1 KR 100243440B1
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KR
South Korea
Prior art keywords
group
substituted
liponucleotide
mercapto
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019950700463A
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English (en)
Korean (ko)
Other versions
KR950702998A (ko
Inventor
질흐 하랄트
헤르만 디터
Original Assignee
로셰 디아그노스틱스 게엠베하
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 로셰 디아그노스틱스 게엠베하 filed Critical 로셰 디아그노스틱스 게엠베하
Publication of KR950702998A publication Critical patent/KR950702998A/ko
Application granted granted Critical
Publication of KR100243440B1 publication Critical patent/KR100243440B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
KR1019950700463A 1992-08-08 1993-08-06 세코-누클레오시드의 리포누클레오티드, 이들의 제조방법 및 항바이러스제로서 이들을 사용하는 방법 Expired - Fee Related KR100243440B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4226279A DE4226279A1 (de) 1992-08-08 1992-08-08 Liponucleotide von Seco-Nucleosiden, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel
DEP4226279.8 1992-08-08
PCT/EP1993/002101 WO1994003465A1 (de) 1992-08-08 1993-08-06 Liponucleotide von seco-nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel

Publications (2)

Publication Number Publication Date
KR950702998A KR950702998A (ko) 1995-08-23
KR100243440B1 true KR100243440B1 (ko) 2000-03-02

Family

ID=6465143

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950700463A Expired - Fee Related KR100243440B1 (ko) 1992-08-08 1993-08-06 세코-누클레오시드의 리포누클레오티드, 이들의 제조방법 및 항바이러스제로서 이들을 사용하는 방법

Country Status (20)

Country Link
EP (1) EP0654036B1 (enExample)
JP (1) JP3479299B2 (enExample)
KR (1) KR100243440B1 (enExample)
CN (1) CN1040984C (enExample)
AT (1) ATE152114T1 (enExample)
AU (1) AU672994B2 (enExample)
CA (1) CA2141030A1 (enExample)
DE (2) DE4226279A1 (enExample)
DK (1) DK0654036T3 (enExample)
ES (1) ES2104163T3 (enExample)
FI (1) FI109699B (enExample)
GR (1) GR3023960T3 (enExample)
HU (1) HUT72605A (enExample)
IL (1) IL106588A (enExample)
MX (1) MX9304676A (enExample)
NO (1) NO304986B1 (enExample)
NZ (1) NZ254813A (enExample)
TW (1) TW306924B (enExample)
WO (1) WO1994003465A1 (enExample)
ZA (1) ZA935718B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817638A (en) * 1988-07-07 1998-10-06 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6252060B1 (en) 1988-07-07 2001-06-26 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
DE4402492A1 (de) * 1994-01-28 1995-08-03 Boehringer Mannheim Gmbh Verfahren zur Herstellung von unsymmetrischen Phosphorsäurediestern
US7517858B1 (en) * 1995-06-07 2009-04-14 The Regents Of The University Of California Prodrugs of pharmaceuticals with improved bioavailability
KR100389558B1 (ko) * 2000-10-11 2003-06-27 주식회사 한스환경엔지니어링 유리섬유 강화플라스틱 성형품의 표면처리용 직물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
DE4026265A1 (de) * 1990-08-20 1992-02-27 Boehringer Mannheim Gmbh Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel

Also Published As

Publication number Publication date
HUT72605A (en) 1996-05-28
JPH08500345A (ja) 1996-01-16
DK0654036T3 (da) 1997-11-03
ES2104163T3 (es) 1997-10-01
CA2141030A1 (en) 1994-02-09
FI950533L (fi) 1995-02-07
EP0654036A1 (de) 1995-05-24
AU4708293A (en) 1994-03-03
MX9304676A (es) 1994-03-31
CN1085908A (zh) 1994-04-27
AU672994B2 (en) 1996-10-24
TW306924B (enExample) 1997-06-01
KR950702998A (ko) 1995-08-23
EP0654036B1 (de) 1997-04-23
GR3023960T3 (en) 1997-09-30
HU9500374D0 (en) 1995-03-28
ATE152114T1 (de) 1997-05-15
NO950445L (no) 1995-02-07
NO304986B1 (no) 1999-03-15
DE59306286D1 (de) 1997-05-28
FI950533A0 (fi) 1995-02-07
JP3479299B2 (ja) 2003-12-15
FI109699B (fi) 2002-09-30
IL106588A0 (en) 1993-12-08
NO950445D0 (no) 1995-02-07
ZA935718B (en) 1995-02-06
WO1994003465A1 (de) 1994-02-17
IL106588A (en) 1998-01-04
NZ254813A (en) 1996-05-28
DE4226279A1 (de) 1994-02-10
CN1040984C (zh) 1998-12-02

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