GR3023960T3 - Liponucleotides of seco-nucleosides, their preparation and their use as anti-viral drugs. - Google Patents
Liponucleotides of seco-nucleosides, their preparation and their use as anti-viral drugs.Info
- Publication number
- GR3023960T3 GR3023960T3 GR970401610T GR970401610T GR3023960T3 GR 3023960 T3 GR3023960 T3 GR 3023960T3 GR 970401610 T GR970401610 T GR 970401610T GR 970401610 T GR970401610 T GR 970401610T GR 3023960 T3 GR3023960 T3 GR 3023960T3
- Authority
- GR
- Greece
- Prior art keywords
- seco
- nucleosides
- liponucleotides
- preparation
- viral drugs
- Prior art date
Links
- 239000002777 nucleoside Substances 0.000 title abstract 3
- 239000003443 antiviral agent Substances 0.000 title abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- RYYWUUFWQRZTIU-UHFFFAOYSA-N Thiophosphoric acid Chemical group OP(O)(S)=O RYYWUUFWQRZTIU-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4226279A DE4226279A1 (de) | 1992-08-08 | 1992-08-08 | Liponucleotide von Seco-Nucleosiden, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel |
| PCT/EP1993/002101 WO1994003465A1 (de) | 1992-08-08 | 1993-08-06 | Liponucleotide von seco-nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3023960T3 true GR3023960T3 (en) | 1997-09-30 |
Family
ID=6465143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR970401610T GR3023960T3 (en) | 1992-08-08 | 1997-06-30 | Liponucleotides of seco-nucleosides, their preparation and their use as anti-viral drugs. |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0654036B1 (el) |
| JP (1) | JP3479299B2 (el) |
| KR (1) | KR100243440B1 (el) |
| CN (1) | CN1040984C (el) |
| AT (1) | ATE152114T1 (el) |
| AU (1) | AU672994B2 (el) |
| CA (1) | CA2141030A1 (el) |
| DE (2) | DE4226279A1 (el) |
| DK (1) | DK0654036T3 (el) |
| ES (1) | ES2104163T3 (el) |
| FI (1) | FI109699B (el) |
| GR (1) | GR3023960T3 (el) |
| HU (1) | HUT72605A (el) |
| IL (1) | IL106588A (el) |
| MX (1) | MX9304676A (el) |
| NO (1) | NO304986B1 (el) |
| NZ (1) | NZ254813A (el) |
| TW (1) | TW306924B (el) |
| WO (1) | WO1994003465A1 (el) |
| ZA (1) | ZA935718B (el) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5817638A (en) * | 1988-07-07 | 1998-10-06 | Nexstar Pharmaceuticals, Inc. | Antiviral liponucleosides: treatment of hepatitis B |
| US6252060B1 (en) | 1988-07-07 | 2001-06-26 | Nexstar Pharmaceuticals, Inc. | Antiviral liponucleosides: treatment of hepatitis B |
| US6599887B2 (en) | 1988-07-07 | 2003-07-29 | Chimerix, Inc. | Methods of treating viral infections using antiviral liponucleotides |
| DE4402492A1 (de) * | 1994-01-28 | 1995-08-03 | Boehringer Mannheim Gmbh | Verfahren zur Herstellung von unsymmetrischen Phosphorsäurediestern |
| US7517858B1 (en) | 1995-06-07 | 2009-04-14 | The Regents Of The University Of California | Prodrugs of pharmaceuticals with improved bioavailability |
| KR100389558B1 (ko) * | 2000-10-11 | 2003-06-27 | 주식회사 한스환경엔지니어링 | 유리섬유 강화플라스틱 성형품의 표면처리용 직물 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223263A (en) * | 1988-07-07 | 1993-06-29 | Vical, Inc. | Liponucleotide-containing liposomes |
| DE4026265A1 (de) * | 1990-08-20 | 1992-02-27 | Boehringer Mannheim Gmbh | Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel |
-
1992
- 1992-08-08 DE DE4226279A patent/DE4226279A1/de not_active Withdrawn
-
1993
- 1993-07-07 TW TW082105422A patent/TW306924B/zh active
- 1993-08-03 MX MX9304676A patent/MX9304676A/es not_active IP Right Cessation
- 1993-08-04 IL IL106588A patent/IL106588A/en not_active IP Right Cessation
- 1993-08-06 AU AU47082/93A patent/AU672994B2/en not_active Ceased
- 1993-08-06 AT AT93917764T patent/ATE152114T1/de not_active IP Right Cessation
- 1993-08-06 WO PCT/EP1993/002101 patent/WO1994003465A1/de active IP Right Grant
- 1993-08-06 KR KR1019950700463A patent/KR100243440B1/ko not_active IP Right Cessation
- 1993-08-06 ZA ZA935718A patent/ZA935718B/xx unknown
- 1993-08-06 JP JP50502594A patent/JP3479299B2/ja not_active Expired - Fee Related
- 1993-08-06 DK DK93917764.8T patent/DK0654036T3/da active
- 1993-08-06 HU HU9500374A patent/HUT72605A/hu unknown
- 1993-08-06 CA CA002141030A patent/CA2141030A1/en not_active Abandoned
- 1993-08-06 NZ NZ254813A patent/NZ254813A/en unknown
- 1993-08-06 DE DE59306286T patent/DE59306286D1/de not_active Expired - Fee Related
- 1993-08-06 ES ES93917764T patent/ES2104163T3/es not_active Expired - Lifetime
- 1993-08-06 EP EP93917764A patent/EP0654036B1/de not_active Expired - Lifetime
- 1993-08-07 CN CN93107987A patent/CN1040984C/zh not_active Expired - Fee Related
-
1995
- 1995-02-07 NO NO950445A patent/NO304986B1/no not_active IP Right Cessation
- 1995-02-07 FI FI950533A patent/FI109699B/fi not_active IP Right Cessation
-
1997
- 1997-06-30 GR GR970401610T patent/GR3023960T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR950702998A (ko) | 1995-08-23 |
| DE4226279A1 (de) | 1994-02-10 |
| ATE152114T1 (de) | 1997-05-15 |
| IL106588A (en) | 1998-01-04 |
| WO1994003465A1 (de) | 1994-02-17 |
| EP0654036B1 (de) | 1997-04-23 |
| KR100243440B1 (ko) | 2000-03-02 |
| DE59306286D1 (de) | 1997-05-28 |
| FI950533A0 (fi) | 1995-02-07 |
| HUT72605A (en) | 1996-05-28 |
| JPH08500345A (ja) | 1996-01-16 |
| NO950445L (no) | 1995-02-07 |
| AU4708293A (en) | 1994-03-03 |
| MX9304676A (es) | 1994-03-31 |
| NZ254813A (en) | 1996-05-28 |
| DK0654036T3 (da) | 1997-11-03 |
| JP3479299B2 (ja) | 2003-12-15 |
| IL106588A0 (en) | 1993-12-08 |
| HU9500374D0 (en) | 1995-03-28 |
| ES2104163T3 (es) | 1997-10-01 |
| FI109699B (fi) | 2002-09-30 |
| EP0654036A1 (de) | 1995-05-24 |
| NO950445D0 (no) | 1995-02-07 |
| AU672994B2 (en) | 1996-10-24 |
| CA2141030A1 (en) | 1994-02-09 |
| TW306924B (el) | 1997-06-01 |
| CN1040984C (zh) | 1998-12-02 |
| CN1085908A (zh) | 1994-04-27 |
| NO304986B1 (no) | 1999-03-15 |
| FI950533A (fi) | 1995-02-07 |
| ZA935718B (en) | 1995-02-06 |
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