FI950533A - Seco-nukleosidien liponulkeotidit, niiden valmistaminen sekä niiden käyttö virusten vastaisina lääkkeinä - Google Patents

Seco-nukleosidien liponulkeotidit, niiden valmistaminen sekä niiden käyttö virusten vastaisina lääkkeinä Download PDF

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Publication number
FI950533A
FI950533A FI950533A FI950533A FI950533A FI 950533 A FI950533 A FI 950533A FI 950533 A FI950533 A FI 950533A FI 950533 A FI950533 A FI 950533A FI 950533 A FI950533 A FI 950533A
Authority
FI
Finland
Prior art keywords
seconucleosides
liponucleotides
preparation
antiviral drugs
seco
Prior art date
Application number
FI950533A
Other languages
English (en)
Swedish (sv)
Other versions
FI950533A0 (fi
FI109699B (fi
Inventor
Harald Zilch
Dieter Herrmann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of FI950533A0 publication Critical patent/FI950533A0/fi
Publication of FI950533A publication Critical patent/FI950533A/fi
Application granted granted Critical
Publication of FI109699B publication Critical patent/FI109699B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI950533A 1992-08-08 1995-02-07 Menetelmä farmakologisesti aktiivisten seco-nukleosidien liponukleotidien valmistamiseksi FI109699B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4226279A DE4226279A1 (de) 1992-08-08 1992-08-08 Liponucleotide von Seco-Nucleosiden, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel
DE4226279 1992-08-08
PCT/EP1993/002101 WO1994003465A1 (de) 1992-08-08 1993-08-06 Liponucleotide von seco-nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
EP9302101 1993-08-06

Publications (3)

Publication Number Publication Date
FI950533A0 FI950533A0 (fi) 1995-02-07
FI950533A true FI950533A (fi) 1995-02-07
FI109699B FI109699B (fi) 2002-09-30

Family

ID=6465143

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950533A FI109699B (fi) 1992-08-08 1995-02-07 Menetelmä farmakologisesti aktiivisten seco-nukleosidien liponukleotidien valmistamiseksi

Country Status (20)

Country Link
EP (1) EP0654036B1 (fi)
JP (1) JP3479299B2 (fi)
KR (1) KR100243440B1 (fi)
CN (1) CN1040984C (fi)
AT (1) ATE152114T1 (fi)
AU (1) AU672994B2 (fi)
CA (1) CA2141030A1 (fi)
DE (2) DE4226279A1 (fi)
DK (1) DK0654036T3 (fi)
ES (1) ES2104163T3 (fi)
FI (1) FI109699B (fi)
GR (1) GR3023960T3 (fi)
HU (1) HUT72605A (fi)
IL (1) IL106588A (fi)
MX (1) MX9304676A (fi)
NO (1) NO304986B1 (fi)
NZ (1) NZ254813A (fi)
TW (1) TW306924B (fi)
WO (1) WO1994003465A1 (fi)
ZA (1) ZA935718B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817638A (en) * 1988-07-07 1998-10-06 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6252060B1 (en) 1988-07-07 2001-06-26 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
DE4402492A1 (de) * 1994-01-28 1995-08-03 Boehringer Mannheim Gmbh Verfahren zur Herstellung von unsymmetrischen Phosphorsäurediestern
US7517858B1 (en) 1995-06-07 2009-04-14 The Regents Of The University Of California Prodrugs of pharmaceuticals with improved bioavailability
KR100389558B1 (ko) * 2000-10-11 2003-06-27 주식회사 한스환경엔지니어링 유리섬유 강화플라스틱 성형품의 표면처리용 직물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
DE4026265A1 (de) * 1990-08-20 1992-02-27 Boehringer Mannheim Gmbh Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel

Also Published As

Publication number Publication date
KR950702998A (ko) 1995-08-23
DE4226279A1 (de) 1994-02-10
ATE152114T1 (de) 1997-05-15
IL106588A (en) 1998-01-04
WO1994003465A1 (de) 1994-02-17
EP0654036B1 (de) 1997-04-23
KR100243440B1 (ko) 2000-03-02
DE59306286D1 (de) 1997-05-28
FI950533A0 (fi) 1995-02-07
HUT72605A (en) 1996-05-28
JPH08500345A (ja) 1996-01-16
NO950445L (no) 1995-02-07
AU4708293A (en) 1994-03-03
MX9304676A (es) 1994-03-31
NZ254813A (en) 1996-05-28
GR3023960T3 (en) 1997-09-30
DK0654036T3 (da) 1997-11-03
JP3479299B2 (ja) 2003-12-15
IL106588A0 (en) 1993-12-08
HU9500374D0 (en) 1995-03-28
ES2104163T3 (es) 1997-10-01
FI109699B (fi) 2002-09-30
EP0654036A1 (de) 1995-05-24
NO950445D0 (no) 1995-02-07
AU672994B2 (en) 1996-10-24
CA2141030A1 (en) 1994-02-09
TW306924B (fi) 1997-06-01
CN1040984C (zh) 1998-12-02
CN1085908A (zh) 1994-04-27
NO304986B1 (no) 1999-03-15
ZA935718B (en) 1995-02-06

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Owner name: ROCHE DIAGNOSTICS GMBH

MA Patent expired