FI950533A - Seco-nukleosidien liponulkeotidit, niiden valmistaminen sekä niiden käyttö virusten vastaisina lääkkeinä - Google Patents

Seco-nukleosidien liponulkeotidit, niiden valmistaminen sekä niiden käyttö virusten vastaisina lääkkeinä Download PDF

Info

Publication number
FI950533A
FI950533A FI950533A FI950533A FI950533A FI 950533 A FI950533 A FI 950533A FI 950533 A FI950533 A FI 950533A FI 950533 A FI950533 A FI 950533A FI 950533 A FI950533 A FI 950533A
Authority
FI
Finland
Prior art keywords
seconucleosides
liponucleotides
preparation
antiviral drugs
seco
Prior art date
Application number
FI950533A
Other languages
English (en)
Swedish (sv)
Other versions
FI950533A0 (fi
FI109699B (fi
Inventor
Harald Zilch
Dieter Herrmann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of FI950533A0 publication Critical patent/FI950533A0/fi
Publication of FI950533A publication Critical patent/FI950533A/fi
Application granted granted Critical
Publication of FI109699B publication Critical patent/FI109699B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI950533A 1992-08-08 1995-02-07 Menetelmä farmakologisesti aktiivisten seco-nukleosidien liponukleotidien valmistamiseksi FI109699B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4226279A DE4226279A1 (de) 1992-08-08 1992-08-08 Liponucleotide von Seco-Nucleosiden, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel
DE4226279 1992-08-08
PCT/EP1993/002101 WO1994003465A1 (de) 1992-08-08 1993-08-06 Liponucleotide von seco-nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
EP9302101 1993-08-06

Publications (3)

Publication Number Publication Date
FI950533A0 FI950533A0 (fi) 1995-02-07
FI950533A true FI950533A (fi) 1995-02-07
FI109699B FI109699B (fi) 2002-09-30

Family

ID=6465143

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950533A FI109699B (fi) 1992-08-08 1995-02-07 Menetelmä farmakologisesti aktiivisten seco-nukleosidien liponukleotidien valmistamiseksi

Country Status (20)

Country Link
EP (1) EP0654036B1 (fi)
JP (1) JP3479299B2 (fi)
KR (1) KR100243440B1 (fi)
CN (1) CN1040984C (fi)
AT (1) ATE152114T1 (fi)
AU (1) AU672994B2 (fi)
CA (1) CA2141030A1 (fi)
DE (2) DE4226279A1 (fi)
DK (1) DK0654036T3 (fi)
ES (1) ES2104163T3 (fi)
FI (1) FI109699B (fi)
GR (1) GR3023960T3 (fi)
HU (1) HUT72605A (fi)
IL (1) IL106588A (fi)
MX (1) MX9304676A (fi)
NO (1) NO304986B1 (fi)
NZ (1) NZ254813A (fi)
TW (1) TW306924B (fi)
WO (1) WO1994003465A1 (fi)
ZA (1) ZA935718B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817638A (en) * 1988-07-07 1998-10-06 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6252060B1 (en) 1988-07-07 2001-06-26 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
DE4402492A1 (de) * 1994-01-28 1995-08-03 Boehringer Mannheim Gmbh Verfahren zur Herstellung von unsymmetrischen Phosphorsäurediestern
US7517858B1 (en) 1995-06-07 2009-04-14 The Regents Of The University Of California Prodrugs of pharmaceuticals with improved bioavailability
KR100389558B1 (ko) * 2000-10-11 2003-06-27 주식회사 한스환경엔지니어링 유리섬유 강화플라스틱 성형품의 표면처리용 직물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
DE4026265A1 (de) * 1990-08-20 1992-02-27 Boehringer Mannheim Gmbh Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel

Also Published As

Publication number Publication date
KR950702998A (ko) 1995-08-23
DE4226279A1 (de) 1994-02-10
ATE152114T1 (de) 1997-05-15
IL106588A (en) 1998-01-04
WO1994003465A1 (de) 1994-02-17
EP0654036B1 (de) 1997-04-23
KR100243440B1 (ko) 2000-03-02
DE59306286D1 (de) 1997-05-28
FI950533A0 (fi) 1995-02-07
HUT72605A (en) 1996-05-28
JPH08500345A (ja) 1996-01-16
NO950445L (no) 1995-02-07
AU4708293A (en) 1994-03-03
MX9304676A (es) 1994-03-31
NZ254813A (en) 1996-05-28
GR3023960T3 (en) 1997-09-30
DK0654036T3 (da) 1997-11-03
JP3479299B2 (ja) 2003-12-15
IL106588A0 (en) 1993-12-08
HU9500374D0 (en) 1995-03-28
ES2104163T3 (es) 1997-10-01
FI109699B (fi) 2002-09-30
EP0654036A1 (de) 1995-05-24
NO950445D0 (no) 1995-02-07
AU672994B2 (en) 1996-10-24
CA2141030A1 (en) 1994-02-09
TW306924B (fi) 1997-06-01
CN1040984C (zh) 1998-12-02
CN1085908A (zh) 1994-04-27
NO304986B1 (no) 1999-03-15
ZA935718B (en) 1995-02-06

Similar Documents

Publication Publication Date Title
MX9202851A (es) Derivados de fosfato de los glucosidos de 4-desmetilepipodofilotoxina y composicion farmaceutica que los contiene.
ES539772A0 (es) Perfeccionamientos en los sistemas de vaporizar agentes ter-micamente vaporizables
FI945363A (fi) Uusia merkaptoasetyyliamidopyridatso (1,2)pyridatsiini-, pyratsolo(1,2)pyridatsiini-, pyridatso (1,2-a)(1,2)diatsepiini- ja pyratsolo(1,2-a)(1,2)diatsepiinijohdannaisia, jotka ovat käyttökelpoisia enkefalisaasin ja ACE:n estäjinä
PT81839B (pt) Processo de preparacao de formulacoes com propulsores de aerosol a base de clorofluorocarbono contendo medicamento
AR002039A1 (es) Pirido[3.2-e]pirazinonas con efecto antiasmatico, y procedimiento para su preparacion y los medicamentos que los contienen y su preparación
MX9203040A (es) Derivados de quinona y composicion farmaceutica que los contiene.
MX9203126A (es) Derivados de sulfonilurea y composiciones farmaceuticas que los contienen.
FI891283A (fi) Ifosfamid-mesna-lyofilisat och foerfarande foer dess framstaellning.
MX9300779A (es) 3-(1h-tetrazol-5-y1)-4h-pyrido[1,2-a]pirimidina-4-onas composiciones farmaceuticas que las contienen y su preparacion de las mismas
ES2043665T3 (es) 6,11-dihidro-11-(4-piperidiliden)-5h-benzo-(5,6)-ciclohepta-(1,2-b)-piridinas y composiciones y metodos de uso.
ES2045484T3 (es) Nuevos derivados de la vitamina d: aplicaciones terapeuticas y a las dosificaciones de los metabolitos de la vitamina d.
FI950533A (fi) Seco-nukleosidien liponulkeotidit, niiden valmistaminen sekä niiden käyttö virusten vastaisina lääkkeinä
GR3004440T3 (fi)
MX9303709A (es) Nucleosidos de purina substituidos e intermediarios de los mismos, que tienen actividad anti-viral y anti-cancerigena y composicion farmaceutica que los contiene.
NO982754L (no) Fosfolipidderivater av fosfonokarboksylsyrer, fremstilling av slike derivater og anvendelse av derivatene som antivirusmedikamenter
IT1233435B (it) Sospensione per la ruota anteriore di motociclette e simili.
DE3777769D1 (de) Pharmazeutische produkte.
NO863791D0 (no) 4-alkoksy-3-pyrrolin-2-on-1-yl-eddiksyrealkylestere samt fremstilling av dem.
MX9304133A (es) Nuevos derivados de los fosfolipidos.
DE68913541D1 (de) Differential mit vier ausgleichsrädern.
ES2032209T3 (es) Derivados de proteinas que contienen hierro en forma altamente biodisponible, su preparacion y composiciones farmaceuticas que los contienen.
IT8820095A0 (it) Uso della vitamina b2 (riboflavina 0 5 fosfato della riboflavina)nnella cura della parodontosi degli anziani.
DK86488A (da) Monobasisk phosphatsalt af dobutamin, fremgangsmaade til fremstilling af et saadant salt samt farmaceutisk praeparat indeholdende saltet
DE3579140D1 (de) Arzneimittel mit einem 6-substituierten adenosin als aktives bestandteil.
FR2577422B1 (fr) Association renfermant a titre de principes actifs, un analgesique central et l'adenine ou l'adenosine ou l'un des analogues de l'adenosine

Legal Events

Date Code Title Description
HC Name/ company changed in application

Owner name: ROCHE DIAGNOSTICS GMBH

MA Patent expired