ES2104163T3 - Liponucleotidos de seco-nucleosidos, su preparacion al igual que su utilizacion como medicamentos antiviricos. - Google Patents

Liponucleotidos de seco-nucleosidos, su preparacion al igual que su utilizacion como medicamentos antiviricos.

Info

Publication number
ES2104163T3
ES2104163T3 ES93917764T ES93917764T ES2104163T3 ES 2104163 T3 ES2104163 T3 ES 2104163T3 ES 93917764 T ES93917764 T ES 93917764T ES 93917764 T ES93917764 T ES 93917764T ES 2104163 T3 ES2104163 T3 ES 2104163T3
Authority
ES
Spain
Prior art keywords
seco
nucleosides
drugs
antiviric
liponucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93917764T
Other languages
English (en)
Inventor
Harald Zilch
Dieter Herrmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2104163T3 publication Critical patent/ES2104163T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A DERIVADOS FOSFOLIPIDOS DE SECONUCLEOSIDOS, EN DONDE UNA PORCION DE LIPIDO, QUE REPRESENTA UN C3 ATO O UN TIOFOSFATO CON UN SECO-NUCLEOSIDO, ASI COMO SU UTILIZACION COMO MEDICAMENTO ANTIVIRAL.
ES93917764T 1992-08-08 1993-08-06 Liponucleotidos de seco-nucleosidos, su preparacion al igual que su utilizacion como medicamentos antiviricos. Expired - Lifetime ES2104163T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4226279A DE4226279A1 (de) 1992-08-08 1992-08-08 Liponucleotide von Seco-Nucleosiden, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel

Publications (1)

Publication Number Publication Date
ES2104163T3 true ES2104163T3 (es) 1997-10-01

Family

ID=6465143

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93917764T Expired - Lifetime ES2104163T3 (es) 1992-08-08 1993-08-06 Liponucleotidos de seco-nucleosidos, su preparacion al igual que su utilizacion como medicamentos antiviricos.

Country Status (20)

Country Link
EP (1) EP0654036B1 (es)
JP (1) JP3479299B2 (es)
KR (1) KR100243440B1 (es)
CN (1) CN1040984C (es)
AT (1) ATE152114T1 (es)
AU (1) AU672994B2 (es)
CA (1) CA2141030A1 (es)
DE (2) DE4226279A1 (es)
DK (1) DK0654036T3 (es)
ES (1) ES2104163T3 (es)
FI (1) FI109699B (es)
GR (1) GR3023960T3 (es)
HU (1) HUT72605A (es)
IL (1) IL106588A (es)
MX (1) MX9304676A (es)
NO (1) NO304986B1 (es)
NZ (1) NZ254813A (es)
TW (1) TW306924B (es)
WO (1) WO1994003465A1 (es)
ZA (1) ZA935718B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817638A (en) * 1988-07-07 1998-10-06 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
US6252060B1 (en) 1988-07-07 2001-06-26 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
DE4402492A1 (de) * 1994-01-28 1995-08-03 Boehringer Mannheim Gmbh Verfahren zur Herstellung von unsymmetrischen Phosphorsäurediestern
US7517858B1 (en) * 1995-06-07 2009-04-14 The Regents Of The University Of California Prodrugs of pharmaceuticals with improved bioavailability
KR100389558B1 (ko) * 2000-10-11 2003-06-27 주식회사 한스환경엔지니어링 유리섬유 강화플라스틱 성형품의 표면처리용 직물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
DE4026265A1 (de) * 1990-08-20 1992-02-27 Boehringer Mannheim Gmbh Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel

Also Published As

Publication number Publication date
IL106588A0 (en) 1993-12-08
ATE152114T1 (de) 1997-05-15
HU9500374D0 (en) 1995-03-28
CN1040984C (zh) 1998-12-02
EP0654036B1 (de) 1997-04-23
KR950702998A (ko) 1995-08-23
TW306924B (es) 1997-06-01
IL106588A (en) 1998-01-04
AU4708293A (en) 1994-03-03
ZA935718B (en) 1995-02-06
CN1085908A (zh) 1994-04-27
NO304986B1 (no) 1999-03-15
WO1994003465A1 (de) 1994-02-17
FI109699B (fi) 2002-09-30
DE59306286D1 (de) 1997-05-28
EP0654036A1 (de) 1995-05-24
FI950533A0 (fi) 1995-02-07
AU672994B2 (en) 1996-10-24
DE4226279A1 (de) 1994-02-10
JP3479299B2 (ja) 2003-12-15
NZ254813A (en) 1996-05-28
JPH08500345A (ja) 1996-01-16
KR100243440B1 (ko) 2000-03-02
MX9304676A (es) 1994-03-31
NO950445D0 (no) 1995-02-07
DK0654036T3 (da) 1997-11-03
FI950533A (fi) 1995-02-07
NO950445L (no) 1995-02-07
GR3023960T3 (en) 1997-09-30
CA2141030A1 (en) 1994-02-09
HUT72605A (en) 1996-05-28

Similar Documents

Publication Publication Date Title
MX9305566A (es) Derivados de urea ciclicos, medicamentos que contienen estos compuestos y procedimientos para su preparacion.
EA200000251A1 (ru) Производные резорцинола
ES2163382T1 (es) Compuestos de papel poli-revestido.
ES540152A0 (es) Un procedimiento para la preparacion de un cosmetico que comprende un fosfato de alquilo.
MX9303466A (es) Derivados de bifenilo, medicamentos que contienen estos compuestos y procedimiento para su preparacion.
ES2126966T3 (es) Proceso para la impregnacion hidrofuga de yeso.
FI891283A (fi) Ifosfamid-mesna-lyofilisat och foerfarande foer dess framstaellning.
ES2019590B3 (es) Productos con contenido fosfolipido, fabricacion de los mismos y empleo.
ES2092981T3 (es) Derivados de aristeromicina/adenosina.
ES2104163T3 (es) Liponucleotidos de seco-nucleosidos, su preparacion al igual que su utilizacion como medicamentos antiviricos.
ES2139669T3 (es) Nuevos derivados triciclicos de indan-2-mercaptoacetilamida 2-substituidos utiles como inhibidores de la encefalinasa.
ES2164869T3 (es) Conjugados lipidos especificos de nucleosidos-difosfato y su uso como medicamentos.
MX9301608A (es) Acidos 7-oxo-7h-pirido(1,2,3,de)(1,4)benzoxacin-6-carboxilico y sus esteres, procedimiento para su preparacion y medicamentos que los contienen.
ES2062997T3 (es) Vinilcefalosporinas sustituidas, procedimiento para su fabricacion y su uso como medicamento.
IT8719367A0 (it) Fosfiti organici resistenti all'idrolisi e procedimento per laloro preparazione.
FR2378518A1 (fr) Nouveaux medicaments a base de derives de tetrahydrodibenzopyranne
ES2061531T3 (es) Derivados de azepinona y azocinona condensados, procedimientos para su preparacion, agentes que los contienen y su utilizacion, asi como productos intermedios en su preparacion.
MX9304133A (es) Nuevos derivados de los fosfolipidos.
PT87092A (pt) Process for the preparation of milbemycin derivatives useful as parasiticides and insecticides
BR9811631A (pt) Derivado de ácido carboxìlico e uso do mesmo
AR222215A1 (es) Procedimiento para la produccion de extractos acuosos de heparina que contienen al menos 120 ui/ml de heparina
MX9204172A (es) Proceso para la preparacion de derivados 4-aza-alfa-androstan-3-ona-17beta- substituidos
FR2381786A1 (fr) Nouveaux aryl-hexafuranosides, leur preparation et leur application en tant que medicaments
MX9304552A (es) Piridoindolobenzodiacepinas y compuestos derivados con actividad antipsicotica y composiciones farma ceuticas que los contienen.
ES2058179T3 (es) Tioeteres fenolicos como inhibidores de 5-lipoxigenasa.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 654036

Country of ref document: ES