HU9500374D0 - Liponucleotides of seco-nucleosides their preparation and their use in antiviral pharmaceutical compositions - Google Patents
Liponucleotides of seco-nucleosides their preparation and their use in antiviral pharmaceutical compositionsInfo
- Publication number
- HU9500374D0 HU9500374D0 HU9500374A HU9500374A HU9500374D0 HU 9500374 D0 HU9500374 D0 HU 9500374D0 HU 9500374 A HU9500374 A HU 9500374A HU 9500374 A HU9500374 A HU 9500374A HU 9500374 D0 HU9500374 D0 HU 9500374D0
- Authority
- HU
- Hungary
- Prior art keywords
- seco
- nucleosides
- liponucleotides
- preparation
- pharmaceutical compositions
- Prior art date
Links
- 239000002777 nucleoside Substances 0.000 title abstract 3
- 230000000840 anti-viral effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- RYYWUUFWQRZTIU-UHFFFAOYSA-N Thiophosphoric acid Chemical group OP(O)(S)=O RYYWUUFWQRZTIU-UHFFFAOYSA-N 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
The invention concerns phospholipid derivatives of seco-nucleosides, in which a lipid with a substituted three-carbon-atom basic structure is linked to a seco-nucleoside via a phosphate or thiophosphate group. The invention also concerns the use of such derivatives as anti-viral drugs.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4226279A DE4226279A1 (en) | 1992-08-08 | 1992-08-08 | Lipo nucleotides of seco-nucleosides, their production and their use as antiviral drugs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HU9500374D0 true HU9500374D0 (en) | 1995-03-28 |
| HUT72605A HUT72605A (en) | 1996-05-28 |
Family
ID=6465143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9500374A HUT72605A (en) | 1992-08-08 | 1993-08-06 | Liponucleotides of seco-nucleosides their preparation and their use in antiviral pharmaceutical compositions |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0654036B1 (en) |
| JP (1) | JP3479299B2 (en) |
| KR (1) | KR100243440B1 (en) |
| CN (1) | CN1040984C (en) |
| AT (1) | ATE152114T1 (en) |
| AU (1) | AU672994B2 (en) |
| CA (1) | CA2141030A1 (en) |
| DE (2) | DE4226279A1 (en) |
| DK (1) | DK0654036T3 (en) |
| ES (1) | ES2104163T3 (en) |
| FI (1) | FI109699B (en) |
| GR (1) | GR3023960T3 (en) |
| HU (1) | HUT72605A (en) |
| IL (1) | IL106588A (en) |
| MX (1) | MX9304676A (en) |
| NO (1) | NO304986B1 (en) |
| NZ (1) | NZ254813A (en) |
| TW (1) | TW306924B (en) |
| WO (1) | WO1994003465A1 (en) |
| ZA (1) | ZA935718B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5817638A (en) * | 1988-07-07 | 1998-10-06 | Nexstar Pharmaceuticals, Inc. | Antiviral liponucleosides: treatment of hepatitis B |
| US6252060B1 (en) | 1988-07-07 | 2001-06-26 | Nexstar Pharmaceuticals, Inc. | Antiviral liponucleosides: treatment of hepatitis B |
| US6599887B2 (en) | 1988-07-07 | 2003-07-29 | Chimerix, Inc. | Methods of treating viral infections using antiviral liponucleotides |
| DE4402492A1 (en) * | 1994-01-28 | 1995-08-03 | Boehringer Mannheim Gmbh | Process for the production of asymmetrical phosphoric acid diesters |
| US7517858B1 (en) | 1995-06-07 | 2009-04-14 | The Regents Of The University Of California | Prodrugs of pharmaceuticals with improved bioavailability |
| KR100389558B1 (en) * | 2000-10-11 | 2003-06-27 | 주식회사 한스환경엔지니어링 | Surface Treating Fabric For FRP |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223263A (en) * | 1988-07-07 | 1993-06-29 | Vical, Inc. | Liponucleotide-containing liposomes |
| DE4026265A1 (en) * | 1990-08-20 | 1992-02-27 | Boehringer Mannheim Gmbh | NEW PHOSPHOLIPID DERIVATIVES OF NUCLEOSIDES, THEIR PRODUCTION AND THEIR USE AS ANTIVIRAL MEDICINAL PRODUCTS |
-
1992
- 1992-08-08 DE DE4226279A patent/DE4226279A1/en not_active Withdrawn
-
1993
- 1993-07-07 TW TW082105422A patent/TW306924B/zh active
- 1993-08-03 MX MX9304676A patent/MX9304676A/en not_active IP Right Cessation
- 1993-08-04 IL IL106588A patent/IL106588A/en not_active IP Right Cessation
- 1993-08-06 AU AU47082/93A patent/AU672994B2/en not_active Ceased
- 1993-08-06 AT AT93917764T patent/ATE152114T1/en not_active IP Right Cessation
- 1993-08-06 WO PCT/EP1993/002101 patent/WO1994003465A1/en active IP Right Grant
- 1993-08-06 KR KR1019950700463A patent/KR100243440B1/en not_active IP Right Cessation
- 1993-08-06 ZA ZA935718A patent/ZA935718B/en unknown
- 1993-08-06 JP JP50502594A patent/JP3479299B2/en not_active Expired - Fee Related
- 1993-08-06 DK DK93917764.8T patent/DK0654036T3/en active
- 1993-08-06 HU HU9500374A patent/HUT72605A/en unknown
- 1993-08-06 CA CA002141030A patent/CA2141030A1/en not_active Abandoned
- 1993-08-06 NZ NZ254813A patent/NZ254813A/en unknown
- 1993-08-06 DE DE59306286T patent/DE59306286D1/en not_active Expired - Fee Related
- 1993-08-06 ES ES93917764T patent/ES2104163T3/en not_active Expired - Lifetime
- 1993-08-06 EP EP93917764A patent/EP0654036B1/en not_active Expired - Lifetime
- 1993-08-07 CN CN93107987A patent/CN1040984C/en not_active Expired - Fee Related
-
1995
- 1995-02-07 NO NO950445A patent/NO304986B1/en not_active IP Right Cessation
- 1995-02-07 FI FI950533A patent/FI109699B/en not_active IP Right Cessation
-
1997
- 1997-06-30 GR GR970401610T patent/GR3023960T3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR950702998A (en) | 1995-08-23 |
| DE4226279A1 (en) | 1994-02-10 |
| ATE152114T1 (en) | 1997-05-15 |
| IL106588A (en) | 1998-01-04 |
| WO1994003465A1 (en) | 1994-02-17 |
| EP0654036B1 (en) | 1997-04-23 |
| KR100243440B1 (en) | 2000-03-02 |
| DE59306286D1 (en) | 1997-05-28 |
| FI950533A0 (en) | 1995-02-07 |
| HUT72605A (en) | 1996-05-28 |
| JPH08500345A (en) | 1996-01-16 |
| NO950445L (en) | 1995-02-07 |
| AU4708293A (en) | 1994-03-03 |
| MX9304676A (en) | 1994-03-31 |
| NZ254813A (en) | 1996-05-28 |
| GR3023960T3 (en) | 1997-09-30 |
| DK0654036T3 (en) | 1997-11-03 |
| JP3479299B2 (en) | 2003-12-15 |
| IL106588A0 (en) | 1993-12-08 |
| ES2104163T3 (en) | 1997-10-01 |
| FI109699B (en) | 2002-09-30 |
| EP0654036A1 (en) | 1995-05-24 |
| NO950445D0 (en) | 1995-02-07 |
| AU672994B2 (en) | 1996-10-24 |
| CA2141030A1 (en) | 1994-02-09 |
| TW306924B (en) | 1997-06-01 |
| CN1040984C (en) | 1998-12-02 |
| CN1085908A (en) | 1994-04-27 |
| NO304986B1 (en) | 1999-03-15 |
| FI950533A (en) | 1995-02-07 |
| ZA935718B (en) | 1995-02-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX9202851A (en) | PHOSPHATE DERIVATIVES OF 4-DESMETILEPIPODOFILOTOXINA GLUCOSIDES AND THE PHARMACEUTICAL COMPOSITION CONTAINING THEM. | |
| AU627845B2 (en) | Improvements in or relating to devices for administration of drugs or the like | |
| IL105727A (en) | 7-(2-mercapto-acetamido)-octahydro-6-oxopyrido[2,1-a][2]-benzazepine derivatives analogs thereof their preparation and pharmaceutical enkephalinase-inhibiting compositions containing them | |
| PL261349A1 (en) | Method of obtaining an incorporative complex of 7-isopropoxyisoflavone with cyclodextrin | |
| CA2085354A1 (en) | Ether lipid-nucleoside covalent conjugates | |
| AU1779488A (en) | Polysaccharides and antiviral drugs containing the same as active ingredient | |
| ES2033426T3 (en) | PROCEDURE FOR THE PREPARATION OF CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS CONTAINING 3'-AZIDO-3'-DEOXYTIMIDINE. | |
| NZ222716A (en) | A lipid composition comprising 97% by weight or greater of phosphatidylcholine | |
| HU9500374D0 (en) | Liponucleotides of seco-nucleosides their preparation and their use in antiviral pharmaceutical compositions | |
| ES8207184A1 (en) | Pharmaceutical composition for oral administration containing cytidine diphosphocholine | |
| NZ222741A (en) | Pharmaceutical compositions containing an interferon and a purine derivative | |
| MY119473A (en) | Novel counterparts of camptothecin, their application as medicine and pharmaceutical compositions containing them | |
| ES8705763A1 (en) | Pharmaceutical compositions containing gels. | |
| SV1996000001A (en) | NEW LISOZYME DIMER APPLICATIONS | |
| JPS6416890A (en) | Antioxidant | |
| ES2032209T3 (en) | DERIVATIVES OF PROTEINS THAT CONTAIN IRON IN A HIGHLY BIOAVAILABLE FORM, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM. | |
| EP0210703A3 (en) | Acylphosphorotriamides useful as lipid-altering agents | |
| AU654670C (en) | New phospholipid derivatives of nucleosides, their preparation and their use as antiviral drugs | |
| IL90848A0 (en) | Lipid derivatives of antiviral nucleosides,their preparation and pharmaceutical compositions containing them | |
| IL88705A0 (en) | Phospholipid derivatives,their preparation and pharmaceutical compositions containing them | |
| IT8720225A0 (en) | COSMETIC COMPOSITIONS CONTAINING CYCLIC ADENOSINE MONOPHOSPHATE AND PHOSPHATIDyl INOSITOL OR INOSITOL AS THE ACTIVE INGREDIENT | |
| IL85398A0 (en) | Cyclopentanemethanol derivatives,their preparation and pharmaceutical compositions containing them |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DGB9 | Succession in title of applicant |
Owner name: HEIDELBERG PHARMA HOLDING GMBH, DE |