FI891283A - Ifosfamid-mesna-lyofilisat och foerfarande foer dess framstaellning. - Google Patents

Ifosfamid-mesna-lyofilisat och foerfarande foer dess framstaellning. Download PDF

Info

Publication number
FI891283A
FI891283A FI891283A FI891283A FI891283A FI 891283 A FI891283 A FI 891283A FI 891283 A FI891283 A FI 891283A FI 891283 A FI891283 A FI 891283A FI 891283 A FI891283 A FI 891283A
Authority
FI
Finland
Prior art keywords
mesna
lyofilisat
ifosfamid
foerfarande foer
foer dess
Prior art date
Application number
FI891283A
Other languages
English (en)
Other versions
FI89456B (fi
FI89456C (fi
FI891283A0 (fi
Inventor
Dieter Sauerbier
Otto Isaac
Wolfgang Peter Brade
Original Assignee
Asta Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Pharma Ag filed Critical Asta Pharma Ag
Publication of FI891283A0 publication Critical patent/FI891283A0/fi
Publication of FI891283A publication Critical patent/FI891283A/fi
Publication of FI89456B publication Critical patent/FI89456B/fi
Application granted granted Critical
Publication of FI89456C publication Critical patent/FI89456C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Control Of El Displays (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI891283A 1988-03-19 1989-03-17 Foerfarande foer framstaellning av ifosfamid-mesna-lyofilisat FI89456C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3809337 1988-03-19
DE3809337 1988-03-19

Publications (4)

Publication Number Publication Date
FI891283A0 FI891283A0 (fi) 1989-03-17
FI891283A true FI891283A (fi) 1989-09-20
FI89456B FI89456B (fi) 1993-06-30
FI89456C FI89456C (fi) 1993-10-11

Family

ID=6350216

Family Applications (1)

Application Number Title Priority Date Filing Date
FI891283A FI89456C (fi) 1988-03-19 1989-03-17 Foerfarande foer framstaellning av ifosfamid-mesna-lyofilisat

Country Status (11)

Country Link
US (1) US4959215A (fi)
EP (1) EP0334083B1 (fi)
JP (1) JP2865698B2 (fi)
AT (1) ATE65402T1 (fi)
CA (1) CA1326452C (fi)
DE (1) DE58900183D1 (fi)
ES (1) ES2040394T3 (fi)
FI (1) FI89456C (fi)
GR (1) GR3002377T3 (fi)
IE (1) IE60721B1 (fi)
PT (1) PT90030B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59101431D1 (de) * 1990-07-16 1994-05-26 Asta Medica Ag Tablette und Granulat welche als Wirkstoff Mesna enthalten.
US5252341A (en) * 1990-07-16 1993-10-12 Degussa Aktiengesellschaft Tablets and granulates containing mesna as active substance
US5227373A (en) * 1991-10-23 1993-07-13 Bristol-Myers Squibb Co. Lyophilized ifosfamide compositions
DE4233842A1 (de) * 1992-10-08 1994-04-14 Asta Medica Ag Mesna Injektionslösungen
WO1995007083A1 (en) * 1993-09-10 1995-03-16 F.H. Faulding & Co. Limited Ifosfamide lyophilisate composition
US5789000A (en) * 1994-11-14 1998-08-04 Bionumerik Pharmaceuticals, Inc. Sterile aqueous parenteral formulations of cis-diammine dichloro platinum
DE19529057B4 (de) * 1995-08-08 2007-12-13 Baxter Healthcare S.A. Ifosfamid-Lyophilisat-Zubereitungen
IT1284973B1 (it) * 1996-10-11 1998-05-28 A R D O Associazione Ricerca E Uso del sodio 2-mercaptoetansolfonato (mesna) in chirurgia
US6613927B1 (en) 2002-02-08 2003-09-02 American Pharmaceutical Partners, Inc. Sterile lyophilized ifosfamide and associated methods
BR0314068A (pt) * 2002-09-05 2005-07-05 Bharat Serums & Vaccines Ltd Processo para a preparação de uma composição estável com baixo nìvel de toxicidade; composição estável que contém oxazafosforina; uso de uma composição estável que contém oxazafosforina; e método de tratamento de uma doença maligna
CA2507848A1 (en) * 2002-12-02 2004-06-17 Bharat Serums & Vaccines Ltd. Ifosfamide compositions for parenteral administration and a process for their preparation
US20070192947A1 (en) * 2003-07-10 2007-08-23 Cylena Medical Technologies Inc. Protective apparel with improved doffing
ES2369776T3 (es) * 2003-10-01 2011-12-05 Baxter International Inc. Nueva utilización, preparados farmacéuticos y procedimiento para su producción.
US20080262084A1 (en) * 2004-09-13 2008-10-23 Gautam Vinod Daftary Stable Emulsion Compositions for Intravenous Administration Having Preservatie Efficacy
US8436190B2 (en) 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
WO2010010383A1 (en) * 2008-07-21 2010-01-28 Isis Innovation Limited Treatment of obesity
WO2010099213A1 (en) * 2009-02-24 2010-09-02 Dekk-Tec, Inc. Complexes of 4-hydroperoxy ifosfamide as anti-tumor agents
EP2994062B1 (en) * 2013-05-07 2019-10-02 AuXin Surgery SA Device for chemically assisted dissection
US20160324809A1 (en) * 2014-01-06 2016-11-10 Auxin Surgery Sa Lyophilized mesna compositions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4220660A (en) * 1977-12-14 1980-09-02 Asta-werke Aktiengesellschaft, Chemische Farik Process for the treatment of humans suffering from undesired urotoxic side effects caused by cytostatically active alkylating agents
DE3111428A1 (de) * 1981-03-24 1982-10-07 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
ZA851062B (en) * 1984-03-01 1985-11-27 Asta Werke Ag Chem Fab Salts of oxazaphosphorine derivatives and process for their production
US4797388A (en) * 1984-05-21 1989-01-10 Cetus Corporation Pharmaceutical compositions with galactitol as carrier
US4859452A (en) * 1986-01-17 1989-08-22 Board Of Regents, The University Of Texas System Methods for the reduction of difluoromethylornithine associated toxicity
DE3768419D1 (de) * 1986-10-07 1991-04-11 Boehringer Biochemia Srl Pharmazeutische zusammensetzungen mit antineoplastischer wirkung.
NO873860L (no) * 1986-10-31 1988-05-02 Asta Pharma Ag Ifosfamid-lyofilisat og fremgangsmaate til deres fremstilling.

Also Published As

Publication number Publication date
CA1326452C (en) 1994-01-25
ES2040394T3 (es) 1993-10-16
IE60721B1 (en) 1994-08-10
JP2865698B2 (ja) 1999-03-08
PT90030B (pt) 1994-05-31
JPH024796A (ja) 1990-01-09
DE58900183D1 (de) 1991-08-29
EP0334083A1 (de) 1989-09-27
IE890854L (en) 1989-09-19
FI89456B (fi) 1993-06-30
FI89456C (fi) 1993-10-11
PT90030A (pt) 1989-11-10
GR3002377T3 (en) 1992-12-30
US4959215A (en) 1990-09-25
FI891283A0 (fi) 1989-03-17
ATE65402T1 (de) 1991-08-15
EP0334083B1 (de) 1991-07-24

Similar Documents

Publication Publication Date Title
FI891283A (fi) Ifosfamid-mesna-lyofilisat och foerfarande foer dess framstaellning.
DK172089D0 (da) 1,3-dioxolanderivater samt fremgangsmaade til fremstilling deraf
FI98913B (fi) Tuholaistorjunta-aineina käyttökelpoiset 2-anilino-pyrimidiinijohdannaiset
ES2124479T3 (es) Composiciones biocidas.
SE8501709D0 (sv) Improvements in or relating to intrleukin therapy
DK501389A (da) Hoereapparat med organer til at undertrykke uoensket tilbagekobling
DK354788D0 (da) Intraokulaer posterior proteselinse
IT1212143B (it) Composizione ad attivita'tricogena.
ES2017982B3 (es) Liofilizado de ifosfamida y procedimiento para su preparacion.
FI892222A0 (fi) Peptidalkoholer med antikoagulantverkan.
DK360888A (da) 3',4'-dinitrogen-substituerede epipodophyllotoxinglucosidderivater
FR2617502B1 (fr) Preparation enzymatique d'anhydro-1,5 d fructose
NO881768D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive 1,3-dioksaner.
RU1797460C (ru) Нематоцидное средство
DE3788028D1 (de) Photosensibilisatoren und polymerisierbare Zusammensetzungen.
KR900700484A (ko) 1,4:3,6-디안히드로 헥시톨 잘산염의 아미노프로판올 유도체,그의 제법 및 약제로서의 그의 용도
IT1230053B (it) Composizione per l'aumento del guadagno di peso.
IT8622051A1 (it) Composizioni farmaceutiche ad attivita' cicatrizzante
MX9203634A (es) Derivados de pirocatecol 3,5-disubstituidos.
SE8504228L (sv) Tumordodande emne
IT1227695B (it) Procedimento per la reversione della tossicita' della bromovinildesossiuridina (bvudr)
IT8705197A0 (it) Calzatura per eliminare l'elettricita' statica.
AR240925A1 (es) "procedimiento para preparar el derivado de guanidinotiazol".
IT8867820A0 (it) Procedimento di preparazione di derivati dell'1,4-benzodiazepina-4-one
LV5470A3 (lv) 3-(2,2-Difluorbenzodioksol-4-il)-4-cianpirola iegusanas panemiens

Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: ASTA MEDICA AKTIENGESELLSCHAFT

MA Patent expired