KR100198183B1 - 퀴논기를 함유하는 티아졸리딘 화합물, 이의 제조방법 및 치료용도 - Google Patents

퀴논기를 함유하는 티아졸리딘 화합물, 이의 제조방법 및 치료용도 Download PDF

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Publication number
KR100198183B1
KR100198183B1 KR1019920025528A KR920025528A KR100198183B1 KR 100198183 B1 KR100198183 B1 KR 100198183B1 KR 1019920025528 A KR1019920025528 A KR 1019920025528A KR 920025528 A KR920025528 A KR 920025528A KR 100198183 B1 KR100198183 B1 KR 100198183B1
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South Korea
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compound
carbon atoms
group
formula
hydrogen atom
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Expired - Fee Related
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KR1019920025528A
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English (en)
Korean (ko)
Inventor
까다까오 요시오
다까히데 니시
스또무 가나이
유이찌 아이자와
와다구니오
다까시 후지따
히로요시 호리꼬시
Original Assignee
가와무라 요시부미
상꾜 가부시키가이샤
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Publication of KR100198183B1 publication Critical patent/KR100198183B1/ko
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019920025528A 1991-12-26 1992-12-24 퀴논기를 함유하는 티아졸리딘 화합물, 이의 제조방법 및 치료용도 Expired - Fee Related KR100198183B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP91-344570 1991-12-26
JP34457091 1991-12-26

Publications (1)

Publication Number Publication Date
KR100198183B1 true KR100198183B1 (ko) 1999-06-15

Family

ID=18370296

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920025528A Expired - Fee Related KR100198183B1 (ko) 1991-12-26 1992-12-24 퀴논기를 함유하는 티아졸리딘 화합물, 이의 제조방법 및 치료용도

Country Status (23)

Country Link
US (1) US5338855A (https=)
EP (1) EP0549366B1 (https=)
JP (1) JP2833948B2 (https=)
KR (1) KR100198183B1 (https=)
CN (1) CN1033639C (https=)
AT (1) ATE165092T1 (https=)
AU (1) AU654222B2 (https=)
CA (1) CA2086179C (https=)
CZ (1) CZ279917B6 (https=)
DE (1) DE69225123T2 (https=)
DK (1) DK0549366T3 (https=)
ES (1) ES2115650T3 (https=)
FI (1) FI925848A7 (https=)
GR (1) GR3026656T3 (https=)
HK (1) HK1007050A1 (https=)
HU (1) HU215448B (https=)
IL (1) IL104237A (https=)
MX (1) MX9207594A (https=)
NO (1) NO302519B1 (https=)
NZ (1) NZ245611A (https=)
RU (1) RU2103265C1 (https=)
TW (1) TW211008B (https=)
ZA (1) ZA9210020B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO302471B1 (no) * 1991-12-26 1998-03-09 Sankyo Co Tiazolidinforbindelser og farmasöytisk preparat
CZ289317B6 (cs) * 1994-04-11 2002-01-16 Sankyo Company Limited Heterocyklická sloučenina, farmaceutický prostředek ji obsahující a její pouľití
IL118474A (en) * 1995-06-01 2001-08-08 Sankyo Co Benzimideol derivatives and pharmaceutical preparations containing them
US6147101A (en) * 1995-06-02 2000-11-14 Kyorin Pharmaceutical Co., Ltd. N-benzyldioxothiazolidylbenzamide derivatives and process for producing the same
US6001862A (en) * 1995-06-02 1999-12-14 Kyorin Pharameuticals Co., Ltd. N-benzyldioxothiazolidylbenzamide derivatives and processes for preparing the same
JP3144624B2 (ja) * 1995-06-02 2001-03-12 杏林製薬株式会社 Ｎ−ベンジルジオキソチアゾリジルベンズアミド誘導体及びその製造法
EP0783888A1 (en) 1995-12-26 1997-07-16 Sankyo Company Limited Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
JPH10338679A (ja) * 1997-04-08 1998-12-22 Mitsubishi Rayon Co Ltd チアゾリジン誘導体の製造方法
US6414123B1 (en) * 1997-10-21 2002-07-02 Vitro Diagnostics, Inc. Method for purifying FSH
US6077849A (en) * 1998-04-02 2000-06-20 Merck & Co., Inc. Antidiabetic agents
US6028088A (en) * 1998-10-30 2000-02-22 The University Of Mississippi Flavonoid derivatives
US6204288B1 (en) 1999-03-08 2001-03-20 The University Of Mississippi 1,2-dithiolane derivatives
US6127394A (en) * 1999-03-08 2000-10-03 The University Of Mississippi 1,2-Dithiolane derivatives
WO2001057007A1 (en) * 2000-02-01 2001-08-09 Kyorin Pharmaceutical Co., Ltd. Alkali metal salt of thiazolidine-2,4-dione derivative
JP4648319B2 (ja) 2003-08-22 2011-03-09 アンティポディーン ファーマシューティカルズ インコーポレイティド ミトコンドリアを標的とする抗酸化剤として使用されるミトキノン誘導体
US7888334B2 (en) 2003-08-22 2011-02-15 Antipodean Pharmaceuticals, Inc. Mitoquinone derivatives used as mitochondrially targeted antioxidants

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725010A (en) * 1986-07-18 1988-02-16 Essex Group, Inc. Control apparatus and method
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
US5120754A (en) * 1988-03-08 1992-06-09 Pfizer Inc. Thiazolidinedione hypoglycemic agents
US5130379A (en) * 1988-03-08 1992-07-14 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
GB8910639D0 (en) * 1989-05-09 1989-06-21 Beecham Group Plc Novel compounds
GB8919434D0 (en) * 1989-08-25 1989-10-11 Beecham Group Plc Novel compounds
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
NO302471B1 (no) * 1991-12-26 1998-03-09 Sankyo Co Tiazolidinforbindelser og farmasöytisk preparat

Also Published As

Publication number Publication date
RU2103265C1 (ru) 1998-01-27
HU9204121D0 (en) 1993-04-28
ZA9210020B (en) 1993-07-02
ES2115650T3 (es) 1998-07-01
DE69225123D1 (de) 1998-05-20
EP0549366A1 (en) 1993-06-30
JP2833948B2 (ja) 1998-12-09
DK0549366T3 (da) 1999-03-08
HU215448B (hu) 1999-04-28
NO924988D0 (no) 1992-12-22
GR3026656T3 (en) 1998-07-31
AU3042992A (en) 1993-07-01
FI925848A7 (fi) 1993-06-27
US5338855A (en) 1994-08-16
ATE165092T1 (de) 1998-05-15
IL104237A (en) 1996-10-16
HK1007050A1 (en) 1999-03-26
EP0549366B1 (en) 1998-04-15
AU654222B2 (en) 1994-10-27
CA2086179C (en) 2000-10-17
NZ245611A (en) 1994-06-27
CA2086179A1 (en) 1993-06-27
NO302519B1 (no) 1998-03-16
FI925848A0 (fi) 1992-12-23
HUT67704A (en) 1995-04-28
CZ389692A3 (en) 1994-01-19
JPH05255288A (ja) 1993-10-05
CN1033639C (zh) 1996-12-25
CZ279917B6 (cs) 1995-08-16
NO924988L (no) 1993-06-28
CN1074679A (zh) 1993-07-28
TW211008B (https=) 1993-08-11
DE69225123T2 (de) 1998-12-24
MX9207594A (es) 1994-06-30

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