DE69225123D1 - Thiazolidinederivate, die eine Quinone-Gruppe enthalten, ihre Herstellung und therapeutische Anwendung - Google Patents

Thiazolidinederivate, die eine Quinone-Gruppe enthalten, ihre Herstellung und therapeutische Anwendung

Info

Publication number
DE69225123D1
DE69225123D1 DE69225123T DE69225123T DE69225123D1 DE 69225123 D1 DE69225123 D1 DE 69225123D1 DE 69225123 T DE69225123 T DE 69225123T DE 69225123 T DE69225123 T DE 69225123T DE 69225123 D1 DE69225123 D1 DE 69225123D1
Authority
DE
Germany
Prior art keywords
preparation
therapeutic use
derivatives containing
thiazolidine derivatives
quinone group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69225123T
Other languages
English (en)
Other versions
DE69225123T2 (de
Inventor
Takao Yoshioka
Takahide Nishi
Tsutomu Kanai
Yuichi Aizawa
Kunio Wada
Takashi Fujita
Hiroyoshi Horikoshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of DE69225123D1 publication Critical patent/DE69225123D1/de
Publication of DE69225123T2 publication Critical patent/DE69225123T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69225123T 1991-12-26 1992-12-24 Thiazolidinederivate, die eine Quinone-Gruppe enthalten, ihre Herstellung und therapeutische Anwendung Expired - Fee Related DE69225123T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34457091 1991-12-26

Publications (2)

Publication Number Publication Date
DE69225123D1 true DE69225123D1 (de) 1998-05-20
DE69225123T2 DE69225123T2 (de) 1998-12-24

Family

ID=18370296

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69225123T Expired - Fee Related DE69225123T2 (de) 1991-12-26 1992-12-24 Thiazolidinederivate, die eine Quinone-Gruppe enthalten, ihre Herstellung und therapeutische Anwendung

Country Status (23)

Country Link
US (1) US5338855A (de)
EP (1) EP0549366B1 (de)
JP (1) JP2833948B2 (de)
KR (1) KR100198183B1 (de)
CN (1) CN1033639C (de)
AT (1) ATE165092T1 (de)
AU (1) AU654222B2 (de)
CA (1) CA2086179C (de)
CZ (1) CZ279917B6 (de)
DE (1) DE69225123T2 (de)
DK (1) DK0549366T3 (de)
ES (1) ES2115650T3 (de)
FI (1) FI925848A (de)
GR (1) GR3026656T3 (de)
HK (1) HK1007050A1 (de)
HU (1) HU215448B (de)
IL (1) IL104237A (de)
MX (1) MX9207594A (de)
NO (1) NO302519B1 (de)
NZ (1) NZ245611A (de)
RU (1) RU2103265C1 (de)
TW (1) TW211008B (de)
ZA (1) ZA9210020B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO302471B1 (no) * 1991-12-26 1998-03-09 Sankyo Co Tiazolidinforbindelser og farmasöytisk preparat
NO305987B1 (no) * 1994-04-11 1999-08-30 Sankyo Co Heterosykliske forbindelser med antidiabetisk aktivitet, deres anvendelse og farmasoeytisk preparat inneholdende disse
CZ293016B6 (cs) * 1995-06-01 2004-01-14 Sankyo Company Limited Benzimidazolové deriváty a farmaceutické prostředky s jejich obsahem
US6147101A (en) * 1995-06-02 2000-11-14 Kyorin Pharmaceutical Co., Ltd. N-benzyldioxothiazolidylbenzamide derivatives and process for producing the same
JP3144624B2 (ja) * 1995-06-02 2001-03-12 杏林製薬株式会社 Ｎ−ベンジルジオキソチアゾリジルベンズアミド誘導体及びその製造法
US6001862A (en) * 1995-06-02 1999-12-14 Kyorin Pharameuticals Co., Ltd. N-benzyldioxothiazolidylbenzamide derivatives and processes for preparing the same
EP0783888A1 (de) * 1995-12-26 1997-07-16 Sankyo Company Limited Verwendung von Troglitazone und verwandten Thiazolidinedionen zur Herstellung eines Medikaments für die Behandlung und Vorbeugung der Osteoporose
JPH10338679A (ja) * 1997-04-08 1998-12-22 Mitsubishi Rayon Co Ltd チアゾリジン誘導体の製造方法
US6414123B1 (en) * 1997-10-21 2002-07-02 Vitro Diagnostics, Inc. Method for purifying FSH
US6077849A (en) * 1998-04-02 2000-06-20 Merck & Co., Inc. Antidiabetic agents
US6028088A (en) * 1998-10-30 2000-02-22 The University Of Mississippi Flavonoid derivatives
US6204288B1 (en) 1999-03-08 2001-03-20 The University Of Mississippi 1,2-dithiolane derivatives
US6127394A (en) * 1999-03-08 2000-10-03 The University Of Mississippi 1,2-Dithiolane derivatives
AU2001228854A1 (en) 2000-02-01 2001-08-14 Kyorin Pharmaceutical Co. Ltd. Alkali metal salt of thiazolidine-2,4-dione derivative
IL173807A (en) 2003-08-22 2014-02-27 Antipodean Pharmaceuticals Inc Antioxidant amphiphilic compounds, histoquinone history and pharmaceutical preparations containing them
US7888334B2 (en) 2003-08-22 2011-02-15 Antipodean Pharmaceuticals, Inc. Mitoquinone derivatives used as mitochondrially targeted antioxidants

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725010A (en) * 1986-07-18 1988-02-16 Essex Group, Inc. Control apparatus and method
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
US5120754A (en) * 1988-03-08 1992-06-09 Pfizer Inc. Thiazolidinedione hypoglycemic agents
US5130379A (en) * 1988-03-08 1992-07-14 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
GB8910639D0 (en) * 1989-05-09 1989-06-21 Beecham Group Plc Novel compounds
GB8919434D0 (en) * 1989-08-25 1989-10-11 Beecham Group Plc Novel compounds
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
NO302471B1 (no) * 1991-12-26 1998-03-09 Sankyo Co Tiazolidinforbindelser og farmasöytisk preparat

Also Published As

Publication number Publication date
CA2086179A1 (en) 1993-06-27
HK1007050A1 (en) 1999-03-26
HU9204121D0 (en) 1993-04-28
AU654222B2 (en) 1994-10-27
AU3042992A (en) 1993-07-01
ES2115650T3 (es) 1998-07-01
HUT67704A (en) 1995-04-28
FI925848A0 (fi) 1992-12-23
GR3026656T3 (en) 1998-07-31
KR100198183B1 (ko) 1999-06-15
TW211008B (de) 1993-08-11
ZA9210020B (en) 1993-07-02
IL104237A (en) 1996-10-16
JP2833948B2 (ja) 1998-12-09
NO924988D0 (no) 1992-12-22
CN1074679A (zh) 1993-07-28
ATE165092T1 (de) 1998-05-15
JPH05255288A (ja) 1993-10-05
US5338855A (en) 1994-08-16
CN1033639C (zh) 1996-12-25
DE69225123T2 (de) 1998-12-24
NZ245611A (en) 1994-06-27
DK0549366T3 (da) 1999-03-08
FI925848A (fi) 1993-06-27
EP0549366B1 (de) 1998-04-15
CZ279917B6 (cs) 1995-08-16
EP0549366A1 (de) 1993-06-30
NO924988L (no) 1993-06-28
MX9207594A (es) 1994-06-30
CZ389692A3 (en) 1994-01-19
RU2103265C1 (ru) 1998-01-27
NO302519B1 (no) 1998-03-16
HU215448B (hu) 1999-04-28
CA2086179C (en) 2000-10-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee