IL104237A - Thiazolidine derivatives containing a quinone group processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents

Thiazolidine derivatives containing a quinone group processes for the preparation thereof and pharmaceutical compositions containing the same

Info

Publication number
IL104237A
IL104237A IL10423792A IL10423792A IL104237A IL 104237 A IL104237 A IL 104237A IL 10423792 A IL10423792 A IL 10423792A IL 10423792 A IL10423792 A IL 10423792A IL 104237 A IL104237 A IL 104237A
Authority
IL
Israel
Prior art keywords
carbon atoms
compound
group
formula
singlet
Prior art date
Application number
IL10423792A
Other languages
English (en)
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of IL104237A publication Critical patent/IL104237A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL10423792A 1991-12-26 1992-12-25 Thiazolidine derivatives containing a quinone group processes for the preparation thereof and pharmaceutical compositions containing the same IL104237A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34457091 1991-12-26

Publications (1)

Publication Number Publication Date
IL104237A true IL104237A (en) 1996-10-16

Family

ID=18370296

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10423792A IL104237A (en) 1991-12-26 1992-12-25 Thiazolidine derivatives containing a quinone group processes for the preparation thereof and pharmaceutical compositions containing the same

Country Status (23)

Country Link
US (1) US5338855A (de)
EP (1) EP0549366B1 (de)
JP (1) JP2833948B2 (de)
KR (1) KR100198183B1 (de)
CN (1) CN1033639C (de)
AT (1) ATE165092T1 (de)
AU (1) AU654222B2 (de)
CA (1) CA2086179C (de)
CZ (1) CZ279917B6 (de)
DE (1) DE69225123T2 (de)
DK (1) DK0549366T3 (de)
ES (1) ES2115650T3 (de)
FI (1) FI925848A7 (de)
GR (1) GR3026656T3 (de)
HK (1) HK1007050A1 (de)
HU (1) HU215448B (de)
IL (1) IL104237A (de)
MX (1) MX9207594A (de)
NO (1) NO302519B1 (de)
NZ (1) NZ245611A (de)
RU (1) RU2103265C1 (de)
TW (1) TW211008B (de)
ZA (1) ZA9210020B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO302471B1 (no) * 1991-12-26 1998-03-09 Sankyo Co Tiazolidinforbindelser og farmasöytisk preparat
CA2146701A1 (en) * 1994-04-11 1995-10-12 Takashi Fujita Heterocyclic compounds having anti-diabetic activity, their preparation and their use
IL118474A (en) * 1995-06-01 2001-08-08 Sankyo Co Benzimideol derivatives and pharmaceutical preparations containing them
US6147101A (en) * 1995-06-02 2000-11-14 Kyorin Pharmaceutical Co., Ltd. N-benzyldioxothiazolidylbenzamide derivatives and process for producing the same
US6001862A (en) * 1995-06-02 1999-12-14 Kyorin Pharameuticals Co., Ltd. N-benzyldioxothiazolidylbenzamide derivatives and processes for preparing the same
JP3144624B2 (ja) * 1995-06-02 2001-03-12 杏林製薬株式会社 Ｎ−ベンジルジオキソチアゾリジルベンズアミド誘導体及びその製造法
EP0783888A1 (de) * 1995-12-26 1997-07-16 Sankyo Company Limited Verwendung von Troglitazone und verwandten Thiazolidinedionen zur Herstellung eines Medikaments für die Behandlung und Vorbeugung der Osteoporose
JPH10338679A (ja) * 1997-04-08 1998-12-22 Mitsubishi Rayon Co Ltd チアゾリジン誘導体の製造方法
US6414123B1 (en) * 1997-10-21 2002-07-02 Vitro Diagnostics, Inc. Method for purifying FSH
US6077849A (en) * 1998-04-02 2000-06-20 Merck & Co., Inc. Antidiabetic agents
US6028088A (en) * 1998-10-30 2000-02-22 The University Of Mississippi Flavonoid derivatives
US6204288B1 (en) 1999-03-08 2001-03-20 The University Of Mississippi 1,2-dithiolane derivatives
US6127394A (en) * 1999-03-08 2000-10-03 The University Of Mississippi 1,2-Dithiolane derivatives
ATE340168T1 (de) * 2000-02-01 2006-10-15 Kyorin Seiyaku Kk Alkalimetallsalz von thiazolidin-2,4-dion- derivaten
CN1839142B (zh) 2003-08-22 2010-06-16 澳新制药公司 用作靶向线粒体的抗氧化剂的线粒体醌衍生物
US7888334B2 (en) 2003-08-22 2011-02-15 Antipodean Pharmaceuticals, Inc. Mitoquinone derivatives used as mitochondrially targeted antioxidants

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725010A (en) * 1986-07-18 1988-02-16 Essex Group, Inc. Control apparatus and method
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
US5130379A (en) * 1988-03-08 1992-07-14 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US5120754A (en) * 1988-03-08 1992-06-09 Pfizer Inc. Thiazolidinedione hypoglycemic agents
GB8910639D0 (en) * 1989-05-09 1989-06-21 Beecham Group Plc Novel compounds
GB8919434D0 (en) * 1989-08-25 1989-10-11 Beecham Group Plc Novel compounds
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
NO302471B1 (no) * 1991-12-26 1998-03-09 Sankyo Co Tiazolidinforbindelser og farmasöytisk preparat

Also Published As

Publication number Publication date
GR3026656T3 (en) 1998-07-31
HU9204121D0 (en) 1993-04-28
NO924988L (no) 1993-06-28
EP0549366B1 (de) 1998-04-15
ZA9210020B (en) 1993-07-02
ATE165092T1 (de) 1998-05-15
AU654222B2 (en) 1994-10-27
EP0549366A1 (de) 1993-06-30
TW211008B (de) 1993-08-11
CZ279917B6 (cs) 1995-08-16
HU215448B (hu) 1999-04-28
DK0549366T3 (da) 1999-03-08
DE69225123D1 (de) 1998-05-20
CA2086179A1 (en) 1993-06-27
ES2115650T3 (es) 1998-07-01
DE69225123T2 (de) 1998-12-24
JPH05255288A (ja) 1993-10-05
US5338855A (en) 1994-08-16
RU2103265C1 (ru) 1998-01-27
CN1074679A (zh) 1993-07-28
MX9207594A (es) 1994-06-30
NO924988D0 (no) 1992-12-22
CA2086179C (en) 2000-10-17
HK1007050A1 (en) 1999-03-26
CZ389692A3 (en) 1994-01-19
NO302519B1 (no) 1998-03-16
AU3042992A (en) 1993-07-01
HUT67704A (en) 1995-04-28
NZ245611A (en) 1994-06-27
FI925848A7 (fi) 1993-06-27
JP2833948B2 (ja) 1998-12-09
CN1033639C (zh) 1996-12-25
KR100198183B1 (ko) 1999-06-15
FI925848A0 (fi) 1992-12-23

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH1 Patent not in force