KR100198046B1 - 사이클로덱스트린과 니메설리드의 포접 화합물, 이의 제조방법 및 이를 함유하는 약제학적 조성물 - Google Patents

사이클로덱스트린과 니메설리드의 포접 화합물, 이의 제조방법 및 이를 함유하는 약제학적 조성물 Download PDF

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Publication number
KR100198046B1
KR100198046B1 KR1019920702903A KR920702903A KR100198046B1 KR 100198046 B1 KR100198046 B1 KR 100198046B1 KR 1019920702903 A KR1019920702903 A KR 1019920702903A KR 920702903 A KR920702903 A KR 920702903A KR 100198046 B1 KR100198046 B1 KR 100198046B1
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KR
South Korea
Prior art keywords
nimesulide
cyclodextrin
compound
solution
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1019920702903A
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English (en)
Korean (ko)
Other versions
KR937000160A (ko
Inventor
비에티 주세페
두비니 엔리카
마피오네 그라차
비디 알도
Original Assignee
브래글리아리카르도
패트팜홀딩 에스 에이
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Publication of KR937000160A publication Critical patent/KR937000160A/ko
Application granted granted Critical
Publication of KR100198046B1 publication Critical patent/KR100198046B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Slide Fasteners, Snap Fasteners, And Hook Fasteners (AREA)
  • Manufacture And Refinement Of Metals (AREA)
  • Ceramic Products (AREA)
  • Fats And Perfumes (AREA)
  • Ink Jet (AREA)
  • Ink Jet Recording Methods And Recording Media Thereof (AREA)
KR1019920702903A 1990-05-22 1991-05-20 사이클로덱스트린과 니메설리드의 포접 화합물, 이의 제조방법 및 이를 함유하는 약제학적 조성물 Expired - Fee Related KR100198046B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT02039390A IT1248475B (it) 1990-05-22 1990-05-22 Composti di inclusione di nimesulide con ciclodestrine
IT20393A/90 1990-05-22
PCT/IT1991/000043 WO1991017774A1 (en) 1990-05-22 1991-05-20 Inclusion compounds of nimesulide with cyclodextrins

Publications (2)

Publication Number Publication Date
KR937000160A KR937000160A (ko) 1993-03-13
KR100198046B1 true KR100198046B1 (ko) 1999-06-15

Family

ID=11166307

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920702903A Expired - Fee Related KR100198046B1 (ko) 1990-05-22 1991-05-20 사이클로덱스트린과 니메설리드의 포접 화합물, 이의 제조방법 및 이를 함유하는 약제학적 조성물

Country Status (14)

Country Link
EP (1) EP0534995B1 (enExample)
JP (1) JP3417942B2 (enExample)
KR (1) KR100198046B1 (enExample)
AT (1) ATE116135T1 (enExample)
AU (1) AU655183B2 (enExample)
DE (1) DE69106361T2 (enExample)
DK (1) DK0534995T3 (enExample)
ES (1) ES2065687T3 (enExample)
FI (1) FI102462B (enExample)
GR (1) GR3015468T3 (enExample)
HU (1) HU214336B (enExample)
IT (1) IT1248475B (enExample)
NO (1) NO304730B1 (enExample)
WO (1) WO1991017774A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1255462B (it) * 1992-07-28 1995-11-02 Grazia Maffione Metodo di preparazione di composti di inclusione di nimesulide con ciclodestrine
HU210922B (en) * 1993-05-24 1995-09-28 Europharmaceuticals Sa Nimesulide alkali salt cyclodextrin inclusion complexes their preparation and pharmaceutical compositions containing them
BE1008307A3 (fr) * 1994-06-16 1996-04-02 Europharmaceuticals Sa Sel de nimesulide hydrosoluble, solution aqueuse le contenant, sa preparation et son utilisation.
BR9509183A (pt) * 1994-10-05 1997-12-30 Helsinn Healthcare Sa Agente antiinflamatório para uso externo
WO1997012608A1 (fr) 1995-10-05 1997-04-10 Helsinn Healthcare S.A. Agent anti-inflammatoire externe
HUP9601442A3 (en) * 1995-07-25 1999-03-29 Panacea Biotec Ltd Nes antinflammatory and analgetic pharmaceutical compositions, containing nimesulid for transdermal use, and process for producing them
HUP9601443A3 (en) * 1996-05-29 1999-03-29 Panacea Biotec Ltd Injectable analgetic pharmaceutical compositions for intramuscular use containing nimesulid, and process for producing them
RU2157689C2 (ru) * 1996-07-24 2000-10-20 Панацея Биотек Лтд. Фармацевтические композиции терапевтического антивоспалительного и болеутоляющего средства для местного нанесения и способ их получения
IN186315B (enExample) * 1996-12-12 2001-08-04 Panacea Biotec Ltd
IT1291895B1 (it) 1997-04-24 1999-01-21 Errekappa Euroterapici S P A Preparazione farmaceutica fluida a base di nimesulide per uso orale e rinofaringeo
WO1999041233A1 (en) * 1998-02-17 1999-08-19 Micio Pharma Chemical Aktiengesellschaft A watersoluble nimesulide adduct also for injectable use
IT1298732B1 (it) * 1998-03-13 2000-02-02 Recordati Chem Pharm Composizioni farmaceutiche orali assumibili senza liquidi,contenenti complessi di inclusione
KR100395247B1 (ko) * 2000-08-30 2003-08-21 디디에스텍주식회사 비자극성 캡사이신 경피 투여 제형
EP1902705A1 (en) * 2006-09-22 2008-03-26 Pharmatex Italia Srl Injectable pharmaceutical nimesulide solutions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR206496A1 (es) * 1972-07-03 1976-07-30 Riker Laboratories Inc Procedimiento para la preparacion de 2-fenoxi-4-nitro-alquil o haloalquilsulfonanilidas

Also Published As

Publication number Publication date
HK1006413A1 (en) 1999-02-26
DE69106361D1 (de) 1995-02-09
HU214336B (hu) 1998-03-02
FI102462B1 (fi) 1998-12-15
EP0534995A1 (en) 1993-04-07
ES2065687T3 (es) 1995-02-16
FI925224L (fi) 1992-11-18
NO924492D0 (no) 1992-11-20
GR3015468T3 (en) 1995-06-30
FI925224A0 (fi) 1992-11-18
IT1248475B (it) 1995-01-19
WO1991017774A1 (en) 1991-11-28
HU9203649D0 (en) 1993-03-29
DK0534995T3 (da) 1995-05-01
NO304730B1 (no) 1999-02-08
EP0534995B1 (en) 1994-12-28
JPH06502842A (ja) 1994-03-31
IT9020393A1 (it) 1991-11-22
IT9020393A0 (enExample) 1990-05-22
ATE116135T1 (de) 1995-01-15
FI102462B (fi) 1998-12-15
JP3417942B2 (ja) 2003-06-16
DE69106361T2 (de) 1995-05-18
NO924492L (no) 1993-01-20
HUT65418A (en) 1994-06-28
AU655183B2 (en) 1994-12-08
AU7866591A (en) 1991-12-10
KR937000160A (ko) 1993-03-13

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