DE69106361T2 - Einschlusskomplex von nimesulide mit cyclodextrinen. - Google Patents

Einschlusskomplex von nimesulide mit cyclodextrinen.

Info

Publication number
DE69106361T2
DE69106361T2 DE69106361T DE69106361T DE69106361T2 DE 69106361 T2 DE69106361 T2 DE 69106361T2 DE 69106361 T DE69106361 T DE 69106361T DE 69106361 T DE69106361 T DE 69106361T DE 69106361 T2 DE69106361 T2 DE 69106361T2
Authority
DE
Germany
Prior art keywords
nimesulide
cyclodextrines
including complex
cyclodextrins
cyclodextrin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69106361T
Other languages
English (en)
Other versions
DE69106361D1 (de
Inventor
Giuseppe Bietti
Enrica Dubini
Grazia Maffione
Aldo Vidi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PATPHARM HOLDING S.A., LUXEMBURG/LUXEMBOURG, LU
Original Assignee
Boehringer Ingelheim Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Italia SpA filed Critical Boehringer Ingelheim Italia SpA
Publication of DE69106361D1 publication Critical patent/DE69106361D1/de
Application granted granted Critical
Publication of DE69106361T2 publication Critical patent/DE69106361T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Medical Informatics (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Manufacture And Refinement Of Metals (AREA)
  • Ink Jet (AREA)
  • Ink Jet Recording Methods And Recording Media Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Ceramic Products (AREA)
  • Slide Fasteners, Snap Fasteners, And Hook Fasteners (AREA)
DE69106361T 1990-05-22 1991-05-20 Einschlusskomplex von nimesulide mit cyclodextrinen. Expired - Fee Related DE69106361T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT02039390A IT1248475B (it) 1990-05-22 1990-05-22 Composti di inclusione di nimesulide con ciclodestrine
PCT/IT1991/000043 WO1991017774A1 (en) 1990-05-22 1991-05-20 Inclusion compounds of nimesulide with cyclodextrins

Publications (2)

Publication Number Publication Date
DE69106361D1 DE69106361D1 (de) 1995-02-09
DE69106361T2 true DE69106361T2 (de) 1995-05-18

Family

ID=11166307

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69106361T Expired - Fee Related DE69106361T2 (de) 1990-05-22 1991-05-20 Einschlusskomplex von nimesulide mit cyclodextrinen.

Country Status (15)

Country Link
EP (1) EP0534995B1 (de)
JP (1) JP3417942B2 (de)
KR (1) KR100198046B1 (de)
AT (1) ATE116135T1 (de)
AU (1) AU655183B2 (de)
DE (1) DE69106361T2 (de)
DK (1) DK0534995T3 (de)
ES (1) ES2065687T3 (de)
FI (1) FI102462B1 (de)
GR (1) GR3015468T3 (de)
HK (1) HK1006413A1 (de)
HU (1) HU214336B (de)
IT (1) IT1248475B (de)
NO (1) NO304730B1 (de)
WO (1) WO1991017774A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1255462B (it) * 1992-07-28 1995-11-02 Grazia Maffione Metodo di preparazione di composti di inclusione di nimesulide con ciclodestrine
HU210922B (en) * 1993-05-24 1995-09-28 Europharmaceuticals Sa Nimesulide alkali salt cyclodextrin inclusion complexes their preparation and pharmaceutical compositions containing them
BE1008307A3 (fr) * 1994-06-16 1996-04-02 Europharmaceuticals Sa Sel de nimesulide hydrosoluble, solution aqueuse le contenant, sa preparation et son utilisation.
DE69522696T2 (de) * 1994-10-05 2002-04-18 Helsinn Healthcare Sa Nimesulid zur aüsserlichen anwendung
HUP9601442A3 (en) * 1995-07-25 1999-03-29 Panacea Biotec Ltd Nes antinflammatory and analgetic pharmaceutical compositions, containing nimesulid for transdermal use, and process for producing them
TR199700409T1 (xx) 1995-10-05 1999-08-23 Helsinn Healthcare S.A. Harici kullan�ma mahsus enflamasyon �nleyici madde.
HUP9601443A3 (en) * 1996-05-29 1999-03-29 Panacea Biotec Ltd Injectable analgetic pharmaceutical compositions for intramuscular use containing nimesulid, and process for producing them
IN186315B (de) * 1996-12-12 2001-08-04 Panacea Biotec Ltd
IT1291895B1 (it) 1997-04-24 1999-01-21 Errekappa Euroterapici S P A Preparazione farmaceutica fluida a base di nimesulide per uso orale e rinofaringeo
WO1999041233A1 (en) * 1998-02-17 1999-08-19 Micio Pharma Chemical Aktiengesellschaft A watersoluble nimesulide adduct also for injectable use
IT1298732B1 (it) * 1998-03-13 2000-02-02 Recordati Chem Pharm Composizioni farmaceutiche orali assumibili senza liquidi,contenenti complessi di inclusione
KR100395247B1 (ko) * 2000-08-30 2003-08-21 디디에스텍주식회사 비자극성 캡사이신 경피 투여 제형
EP1902705A1 (de) * 2006-09-22 2008-03-26 Pharmatex Italia Srl Injizierbare pharmazeutische Lösungen mit Nimesulid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR206496A1 (es) * 1972-07-03 1976-07-30 Riker Laboratories Inc Procedimiento para la preparacion de 2-fenoxi-4-nitro-alquil o haloalquilsulfonanilidas

Also Published As

Publication number Publication date
HK1006413A1 (en) 1999-02-26
NO304730B1 (no) 1999-02-08
FI102462B (fi) 1998-12-15
IT9020393A1 (it) 1991-11-22
FI925224A (fi) 1992-11-18
KR100198046B1 (ko) 1999-06-15
IT1248475B (it) 1995-01-19
FI102462B1 (fi) 1998-12-15
JP3417942B2 (ja) 2003-06-16
FI925224A0 (fi) 1992-11-18
DE69106361D1 (de) 1995-02-09
JPH06502842A (ja) 1994-03-31
HU9203649D0 (en) 1993-03-29
AU655183B2 (en) 1994-12-08
NO924492D0 (no) 1992-11-20
AU7866591A (en) 1991-12-10
ATE116135T1 (de) 1995-01-15
DK0534995T3 (da) 1995-05-01
EP0534995A1 (de) 1993-04-07
HU214336B (hu) 1998-03-02
NO924492L (no) 1993-01-20
GR3015468T3 (en) 1995-06-30
IT9020393A0 (de) 1990-05-22
KR937000160A (ko) 1993-03-13
ES2065687T3 (es) 1995-02-16
WO1991017774A1 (en) 1991-11-28
EP0534995B1 (de) 1994-12-28
HUT65418A (en) 1994-06-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: HELSINN BIREX PHARMACEUTICALS LTD., DUBLIN, IE

8327 Change in the person/name/address of the patent owner

Owner name: PATPHARM HOLDING S.A., LUXEMBURG/LUXEMBOURG, LU

8339 Ceased/non-payment of the annual fee