DK0501267T3 - Inklusionsforbindelser af apocarotenal eller lycopen i en cyclodextrin - Google Patents

Inklusionsforbindelser af apocarotenal eller lycopen i en cyclodextrin

Info

Publication number
DK0501267T3
DK0501267T3 DK92102587T DK92102587T DK0501267T3 DK 0501267 T3 DK0501267 T3 DK 0501267T3 DK 92102587 T DK92102587 T DK 92102587T DK 92102587 T DK92102587 T DK 92102587T DK 0501267 T3 DK0501267 T3 DK 0501267T3
Authority
DK
Denmark
Prior art keywords
apocarotenal
lycopene
cyclodextrin
inclusion compounds
water
Prior art date
Application number
DK92102587T
Other languages
English (en)
Inventor
Bruno Leuenberger
Hansjoerg Stoller
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0501267T3 publication Critical patent/DK0501267T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/14—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
DK92102587T 1991-02-25 1992-02-17 Inklusionsforbindelser af apocarotenal eller lycopen i en cyclodextrin DK0501267T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH55691 1991-02-25

Publications (1)

Publication Number Publication Date
DK0501267T3 true DK0501267T3 (da) 1999-01-18

Family

ID=4189738

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92102587T DK0501267T3 (da) 1991-02-25 1992-02-17 Inklusionsforbindelser af apocarotenal eller lycopen i en cyclodextrin

Country Status (6)

Country Link
US (1) US5221735A (da)
EP (1) EP0501267B1 (da)
JP (1) JP3162465B2 (da)
AT (1) ATE165012T1 (da)
DE (1) DE59209277D1 (da)
DK (1) DK0501267T3 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532009A (en) * 1995-06-07 1996-07-02 The Procter & Gamble Company Fat substitutes containing water soluble beta-carotene
US6007856A (en) * 1997-08-08 1999-12-28 The Procter & Gamble Company Oil-in-water dispersions of β-carotene and other carotenoids stable against oxidation prepared from water-dispersible beadlets having high concentrations of carotenoid
JP4859006B2 (ja) * 2001-05-25 2012-01-18 富士化学工業株式会社 安定なアスタキサンチン−シクロデキストリン包接化合物及びその製造方法、並びに該包接化合物を含有する液剤、飲食物、飼料、医薬品及び化粧品
JP5041565B2 (ja) * 2001-05-25 2012-10-03 富士化学工業株式会社 安定なアスタキサンチンとγ−シクロデキストリンとの包接化合物及びその製造方法、並びに液剤、飲食物、飼料、医薬品及び化粧品用途
CN1232539C (zh) * 2002-05-10 2005-12-21 刘云清 有机药物与倍他环糊精衍生物的配合物及其制备方法
AU2003258890A1 (en) * 2002-07-04 2004-01-23 Poltec As Complexes of cyclodextrins and carotenoids
US7446101B1 (en) * 2003-12-12 2008-11-04 Bioactives, Llc Bioavailable carotenoid-cyclodextrin formulations for soft-gels and other encapsulation systems
US7781572B2 (en) * 2005-10-05 2010-08-24 Nse Products, Inc. Nanosized carotenoid cyclodextrin complexes
CN100390227C (zh) * 2006-01-19 2008-05-28 南京师范大学 β-环糊精和羟丙基-β-环糊精混合包合番茄红素的组合物及其制备方法
US8410079B2 (en) * 2010-08-06 2013-04-02 Island Kinetics Chirally correct retinal cyclodextrin hemiacetals for clarifying skin complexion
CN105903028B (zh) * 2010-12-31 2020-10-16 东塘实验室有限公司 含有环糊精的细胞水合组合物
US20120171184A1 (en) 2010-12-31 2012-07-05 Lajos Szente Cellular hydration compositions
WO2012090018A1 (en) * 2010-12-31 2012-07-05 Eastpond Laboratories Limited Cellular hydration compositions containing cyclodextrins
JP2020196683A (ja) * 2019-06-03 2020-12-10 三井化学株式会社 水溶液及び抗菌剤
JP7415104B2 (ja) * 2019-06-03 2024-01-17 三井化学株式会社 ジヨードメタン化合物の水溶液の製造方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1050167B (de) * 1959-02-05 E. Hoffmann-La Roche 6- Co. Aktiengesellschaft, Basel (Schweiz) Verfahren zur Herstellung eines Präparates zum Färben von Nahrungsmitteln
US4054736A (en) * 1970-06-10 1977-10-18 Ono Pharmaceutical Co., Ltd. Clathrate compounds of prostaglandins or their analogues with cyclodextrin
US4371673A (en) * 1980-07-21 1983-02-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble forms of retinoids
HU190818B (en) * 1982-11-09 1986-11-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for producing complexes of piperonyl-butoxide-cyclodextrin
GB2162529B (en) * 1984-06-08 1988-03-02 Nitrokemia Ipartelepek B-cyclodextrin complex of benzene sulphonyl urea derivatives
US4883785A (en) * 1984-07-27 1989-11-28 Chow Wing Sun Complex of anti-fungal agent and cyclodextrin and method
HU199444B (en) * 1985-09-10 1990-02-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 7-isopropoxy-isoflavone-cyclodextrene inclusion complex and pharmaceutical compositions therefrom
JPH0647585B2 (ja) * 1986-02-26 1994-06-22 日清製粉株式会社 ビタミンｅエステル類の包接化合物
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten
JPS62267261A (ja) * 1986-05-14 1987-11-19 Ichimaru Pharcos Co Ltd β−カロチン包接物
DE3815902A1 (de) * 1988-05-10 1989-11-23 Schwarz Pharma Gmbh Einschlussverbindungen des 1-(4-(2-(5-chloro-2-methoxybenzamido)ethyl) -phenylsulfonyl)-3-cyclohexylharnstoffs mit (alpha)-,ss-,(gamma)-cyclodextrinen, jeweils diese enthaltendes pharmazeutisches praeparat und verfahren zu deren herstellung
WO1989010739A1 (en) * 1988-05-11 1989-11-16 Board Of Regents, The University Of Texas System Hydroxyalkyl cyclodextrin-antifungal polyene antibiotics complexes
US5007966A (en) * 1988-09-21 1991-04-16 American Maize-Products Company Cyclodextrin complexing method
DE69020408T2 (de) * 1989-04-12 1996-01-04 Procter & Gamble Festes Verbraucherprodukt, welches feinteilige Cyclodextrin-Komplexe enthält.

Also Published As

Publication number Publication date
US5221735A (en) 1993-06-22
ATE165012T1 (de) 1998-05-15
EP0501267A1 (de) 1992-09-02
DE59209277D1 (de) 1998-05-20
EP0501267B1 (de) 1998-04-15
JPH07165801A (ja) 1995-06-27
JP3162465B2 (ja) 2001-04-25

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