ATE165012T1 - Einschlussverbindungen von apocarotinal oder lycopin in einem cyclodextrin - Google Patents

Einschlussverbindungen von apocarotinal oder lycopin in einem cyclodextrin

Info

Publication number
ATE165012T1
ATE165012T1 AT92102587T AT92102587T ATE165012T1 AT E165012 T1 ATE165012 T1 AT E165012T1 AT 92102587 T AT92102587 T AT 92102587T AT 92102587 T AT92102587 T AT 92102587T AT E165012 T1 ATE165012 T1 AT E165012T1
Authority
AT
Austria
Prior art keywords
cyclodextrin
apocarotinal
lycopine
including compounds
water
Prior art date
Application number
AT92102587T
Other languages
English (en)
Inventor
Bruno Leuenberger
Hansjoerg Stoller
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE165012T1 publication Critical patent/ATE165012T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/14Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
AT92102587T 1991-02-25 1992-02-17 Einschlussverbindungen von apocarotinal oder lycopin in einem cyclodextrin ATE165012T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH55691 1991-02-25

Publications (1)

Publication Number Publication Date
ATE165012T1 true ATE165012T1 (de) 1998-05-15

Family

ID=4189738

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92102587T ATE165012T1 (de) 1991-02-25 1992-02-17 Einschlussverbindungen von apocarotinal oder lycopin in einem cyclodextrin

Country Status (6)

Country Link
US (1) US5221735A (de)
EP (1) EP0501267B1 (de)
JP (1) JP3162465B2 (de)
AT (1) ATE165012T1 (de)
DE (1) DE59209277D1 (de)
DK (1) DK0501267T3 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532009A (en) * 1995-06-07 1996-07-02 The Procter & Gamble Company Fat substitutes containing water soluble beta-carotene
US6007856A (en) * 1997-08-08 1999-12-28 The Procter & Gamble Company Oil-in-water dispersions of β-carotene and other carotenoids stable against oxidation prepared from water-dispersible beadlets having high concentrations of carotenoid
JP5041565B2 (ja) * 2001-05-25 2012-10-03 富士化学工業株式会社 安定なアスタキサンチンとγ−シクロデキストリンとの包接化合物及びその製造方法、並びに液剤、飲食物、飼料、医薬品及び化粧品用途
JP4859006B2 (ja) * 2001-05-25 2012-01-18 富士化学工業株式会社 安定なアスタキサンチン−シクロデキストリン包接化合物及びその製造方法、並びに該包接化合物を含有する液剤、飲食物、飼料、医薬品及び化粧品
CN1232539C (zh) * 2002-05-10 2005-12-21 刘云清 有机药物与倍他环糊精衍生物的配合物及其制备方法
AU2003258890A1 (en) * 2002-07-04 2004-01-23 Poltec As Complexes of cyclodextrins and carotenoids
US7446101B1 (en) * 2003-12-12 2008-11-04 Bioactives, Llc Bioavailable carotenoid-cyclodextrin formulations for soft-gels and other encapsulation systems
US7781572B2 (en) * 2005-10-05 2010-08-24 Nse Products, Inc. Nanosized carotenoid cyclodextrin complexes
CN100390227C (zh) * 2006-01-19 2008-05-28 南京师范大学 β-环糊精和羟丙基-β-环糊精混合包合番茄红素的组合物及其制备方法
US8410079B2 (en) * 2010-08-06 2013-04-02 Island Kinetics Chirally correct retinal cyclodextrin hemiacetals for clarifying skin complexion
EP2658578A1 (de) * 2010-12-31 2013-11-06 Eastpond Laboratories Limited Zellulare hydratationszusammensetzungen mit cyclodextrinen
US20120171184A1 (en) 2010-12-31 2012-07-05 Lajos Szente Cellular hydration compositions
CN105903028B (zh) * 2010-12-31 2020-10-16 东塘实验室有限公司 含有环糊精的细胞水合组合物
JP2020196683A (ja) * 2019-06-03 2020-12-10 三井化学株式会社 水溶液及び抗菌剤
JP7415104B2 (ja) * 2019-06-03 2024-01-17 三井化学株式会社 ジヨードメタン化合物の水溶液の製造方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1050167B (de) * 1959-02-05 E. Hoffmann-La Roche 6- Co. Aktiengesellschaft, Basel (Schweiz) Verfahren zur Herstellung eines Präparates zum Färben von Nahrungsmitteln
US4054736A (en) * 1970-06-10 1977-10-18 Ono Pharmaceutical Co., Ltd. Clathrate compounds of prostaglandins or their analogues with cyclodextrin
US4371673A (en) * 1980-07-21 1983-02-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble forms of retinoids
HU190818B (en) * 1982-11-09 1986-11-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for producing complexes of piperonyl-butoxide-cyclodextrin
GB2162529B (en) * 1984-06-08 1988-03-02 Nitrokemia Ipartelepek B-cyclodextrin complex of benzene sulphonyl urea derivatives
US4883785A (en) * 1984-07-27 1989-11-28 Chow Wing Sun Complex of anti-fungal agent and cyclodextrin and method
HU199444B (en) * 1985-09-10 1990-02-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 7-isopropoxy-isoflavone-cyclodextrene inclusion complex and pharmaceutical compositions therefrom
JPH0647585B2 (ja) * 1986-02-26 1994-06-22 日清製粉株式会社 ビタミンeエステル類の包接化合物
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten
JPS62267261A (ja) * 1986-05-14 1987-11-19 Ichimaru Pharcos Co Ltd β−カロチン包接物
DE3815902A1 (de) * 1988-05-10 1989-11-23 Schwarz Pharma Gmbh Einschlussverbindungen des 1-(4-(2-(5-chloro-2-methoxybenzamido)ethyl) -phenylsulfonyl)-3-cyclohexylharnstoffs mit (alpha)-,ss-,(gamma)-cyclodextrinen, jeweils diese enthaltendes pharmazeutisches praeparat und verfahren zu deren herstellung
WO1989010739A1 (en) * 1988-05-11 1989-11-16 Board Of Regents, The University Of Texas System Hydroxyalkyl cyclodextrin-antifungal polyene antibiotics complexes
US5007966A (en) * 1988-09-21 1991-04-16 American Maize-Products Company Cyclodextrin complexing method
ES2073507T3 (es) * 1989-04-12 1995-08-16 Procter & Gamble Composiciones de productos solidos de consumo que contienen complejos con ciclodextrina en forma de pequeñas particulas.

Also Published As

Publication number Publication date
EP0501267B1 (de) 1998-04-15
DK0501267T3 (da) 1999-01-18
US5221735A (en) 1993-06-22
EP0501267A1 (de) 1992-09-02
JP3162465B2 (ja) 2001-04-25
JPH07165801A (ja) 1995-06-27
DE59209277D1 (de) 1998-05-20

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee