DK0468258T3 - Substituerede pyridooxaziner - Google Patents

Substituerede pyridooxaziner

Info

Publication number
DK0468258T3
DK0468258T3 DK91111273.8T DK91111273T DK0468258T3 DK 0468258 T3 DK0468258 T3 DK 0468258T3 DK 91111273 T DK91111273 T DK 91111273T DK 0468258 T3 DK0468258 T3 DK 0468258T3
Authority
DK
Denmark
Prior art keywords
substituted
pyridooxazines
lipoproteinaemia
hyperlipoproteinaemia
oxazines
Prior art date
Application number
DK91111273.8T
Other languages
English (en)
Inventor
Peter Dr Fey
Hilmar Dr Bischoff
Delf Dr Schmidt
Rolf Dr Angerbauer
Walter Dr Huebsch
Joachim Dr Bender
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0468258T3 publication Critical patent/DK0468258T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK91111273.8T 1990-07-21 1991-07-06 Substituerede pyridooxaziner DK0468258T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4023308A DE4023308A1 (de) 1990-07-21 1990-07-21 Substituierte pyrido-oxazine

Publications (1)

Publication Number Publication Date
DK0468258T3 true DK0468258T3 (da) 1996-02-26

Family

ID=6410808

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91111273.8T DK0468258T3 (da) 1990-07-21 1991-07-06 Substituerede pyridooxaziner

Country Status (9)

Country Link
US (1) US5137881A (da)
EP (1) EP0468258B1 (da)
JP (1) JPH04305581A (da)
AT (1) ATE129712T1 (da)
CA (1) CA2047327A1 (da)
DE (2) DE4023308A1 (da)
DK (1) DK0468258T3 (da)
ES (1) ES2080855T3 (da)
GR (1) GR3017967T3 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9223371D0 (en) * 1992-11-06 1992-12-23 Ici Plc Heterocyclic compounds
DE4244029A1 (de) * 1992-12-24 1994-06-30 Bayer Ag Neue substituierte Pyridine
AR008789A1 (es) 1996-07-31 2000-02-23 Bayer Corp Piridinas y bifenilos substituidos
US7371759B2 (en) 2003-09-25 2008-05-13 Bristol-Myers Squibb Company HMG-CoA reductase inhibitors and method
US7420059B2 (en) * 2003-11-20 2008-09-02 Bristol-Myers Squibb Company HMG-CoA reductase inhibitors and method
US8367669B2 (en) * 2005-06-15 2013-02-05 Vanderbilt University Inhibitors of hemeprotein-catalyzed lipid peroxidation
US9133212B1 (en) 2005-06-15 2015-09-15 Vanderbilt University Inhibitors of hemeprotein-catalyzed lipid peroxidation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE397044C (de) * 1923-05-15 1924-06-25 Leveugle Freres Soc Wasserrohrkessel mit zwei nebeneinanderliegenden Dampf- und Wassersammlern
US3838120A (en) * 1972-12-07 1974-09-24 Sterling Drug Inc 1-alkyl-1h,4h-pyrido(2,3-d)(1,3)oxazine-2,4-diones and their conversion to 1-alkyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids
US4518602A (en) * 1982-10-07 1985-05-21 Takeda Chemical Industries, Ltd. Vinyl carboxylic acid derivatives, their production and use as inhibitors of thromboxane synthetase
US4874775A (en) * 1985-06-11 1989-10-17 Eli Lilly And Company Agriculturally useful sulfonamides
FI87927C (fi) * 1987-05-22 1993-03-10 Squibb & Sons Inc Foerfarande foer framstaellining av nya fosforhaltiga hmg-coa-reduktasinhibitorer och nya mellanprodukter
JPH02237988A (ja) * 1988-11-18 1990-09-20 Nissan Chem Ind Ltd イソオキサゾロピリジン系メバロノラクトン類

Also Published As

Publication number Publication date
DE59106803D1 (de) 1995-12-07
EP0468258B1 (de) 1995-11-02
ATE129712T1 (de) 1995-11-15
ES2080855T3 (es) 1996-02-16
EP0468258A1 (de) 1992-01-29
US5137881A (en) 1992-08-11
JPH04305581A (ja) 1992-10-28
DE4023308A1 (de) 1992-01-23
GR3017967T3 (en) 1996-02-29
CA2047327A1 (en) 1992-01-22

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