KR0183012B1 - 알파-글리코시다제 억제제 - Google Patents

알파-글리코시다제 억제제 Download PDF

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Publication number
KR0183012B1
KR0183012B1 KR1019900016003A KR900016003A KR0183012B1 KR 0183012 B1 KR0183012 B1 KR 0183012B1 KR 1019900016003 A KR1019900016003 A KR 1019900016003A KR 900016003 A KR900016003 A KR 900016003A KR 0183012 B1 KR0183012 B1 KR 0183012B1
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KR
South Korea
Prior art keywords
benzyl
methyl
tri
dideoxy
imino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019900016003A
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English (en)
Korean (ko)
Other versions
KR910007951A (ko
Inventor
뒤셉 쟝-베르나드
당젱 샤를르
Original Assignee
개리 디. 스트리트
메렐 다우 파마슈티칼스 인코퍼레이티드
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Publication date
Application filed by 개리 디. 스트리트, 메렐 다우 파마슈티칼스 인코퍼레이티드 filed Critical 개리 디. 스트리트
Publication of KR910007951A publication Critical patent/KR910007951A/ko
Application granted granted Critical
Publication of KR0183012B1 publication Critical patent/KR0183012B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044—Pyrrole radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Child & Adolescent Psychology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1019900016003A 1989-10-10 1990-10-10 알파-글리코시다제 억제제 Expired - Fee Related KR0183012B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP89402794A EP0422307A1 (en) 1989-10-10 1989-10-10 Novel alpha-glucosidase inhibitors
EP894027945 1989-10-10

Publications (2)

Publication Number Publication Date
KR910007951A KR910007951A (ko) 1991-05-30
KR0183012B1 true KR0183012B1 (ko) 1999-04-01

Family

ID=8202997

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900016003A Expired - Fee Related KR0183012B1 (ko) 1989-10-10 1990-10-10 알파-글리코시다제 억제제

Country Status (21)

Country Link
US (1) US5097023A (cg-RX-API-DMAC10.html)
EP (2) EP0422307A1 (cg-RX-API-DMAC10.html)
JP (1) JP3032266B2 (cg-RX-API-DMAC10.html)
KR (1) KR0183012B1 (cg-RX-API-DMAC10.html)
CN (1) CN1029974C (cg-RX-API-DMAC10.html)
AR (1) AR246745A1 (cg-RX-API-DMAC10.html)
AT (1) ATE109153T1 (cg-RX-API-DMAC10.html)
AU (1) AU632855B2 (cg-RX-API-DMAC10.html)
CA (1) CA2027276C (cg-RX-API-DMAC10.html)
DE (1) DE69011033T2 (cg-RX-API-DMAC10.html)
DK (1) DK0422975T3 (cg-RX-API-DMAC10.html)
ES (1) ES2060980T3 (cg-RX-API-DMAC10.html)
FI (1) FI101796B (cg-RX-API-DMAC10.html)
HU (1) HU209724B (cg-RX-API-DMAC10.html)
IE (1) IE64079B1 (cg-RX-API-DMAC10.html)
IL (1) IL95928A (cg-RX-API-DMAC10.html)
NO (1) NO174203C (cg-RX-API-DMAC10.html)
NZ (1) NZ235578A (cg-RX-API-DMAC10.html)
PT (1) PT95547B (cg-RX-API-DMAC10.html)
TW (1) TW225539B (cg-RX-API-DMAC10.html)
ZA (1) ZA907936B (cg-RX-API-DMAC10.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504078A (en) * 1990-06-08 1996-04-02 Merrell Dow Pharmaceuticals Inc. α-glucosidase inhibitors
US5268364A (en) * 1991-12-12 1993-12-07 The Biomembrane Institute Method for inhibiting selectin-dependent adhesion of leukocytes and platelets by O-glycosylation modification
US5843921A (en) 1994-03-15 1998-12-01 Childrens Hospital Of Los Angeles Therapeutic food composition and method to diminish blood sugar fluctuations
US5605893A (en) * 1994-03-15 1997-02-25 Children's Hospital Of Los Angeles Method of using a therapeutic food composition to diminish blood sugar fluctuations in diabetic patients
JP3580900B2 (ja) * 1995-04-20 2004-10-27 ホクレン農業協同組合連合会 α−グルコシダーゼ阻害剤を含む糖を主体とする組成物を有効成分とする食品及び飼料
US5929037A (en) * 1995-06-07 1999-07-27 Alberta Research Council Modified α-D-Glcρ-(1-2)-α-D-Glcρ-(1-3)-α-D-Glcρ-analogues
EP0858335B1 (en) * 1995-09-08 2003-03-12 Novo Nordisk A/S 2-alkylpyrrolidines
WO1998009981A1 (en) * 1996-09-09 1998-03-12 Wisconsin Alumni Research Foundation Human salivary proteins and fragments thereof having alpha-glucosidase inhibitory activity
US6534487B1 (en) 1999-08-03 2003-03-18 Childrens Hospital Los Angeles Methods for suppressing appetite and enhancing exercise and recovery
EP1270598A4 (en) * 1999-12-21 2003-05-02 Ajinomoto Kk PARTIAL ESTER OF CELLULOSE WITH NITROGEN CARBOXYLIC ACID AND PRODUCTION METHOD
JP4486792B2 (ja) * 2003-06-12 2010-06-23 学校法人近畿大学 環状オニウム化合物およびグルコシダーゼ阻害剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.

Also Published As

Publication number Publication date
IE903613A1 (en) 1991-04-24
JPH03127797A (ja) 1991-05-30
FI101796B1 (fi) 1998-08-31
KR910007951A (ko) 1991-05-30
NZ235578A (en) 1992-10-28
AU632855B2 (en) 1993-01-14
ES2060980T3 (es) 1994-12-01
FI904965A0 (fi) 1990-10-09
NO174203B (no) 1993-12-20
AR246745A1 (es) 1994-09-30
CA2027276A1 (en) 1991-04-11
PT95547A (pt) 1991-08-14
US5097023A (en) 1992-03-17
EP0422975B1 (en) 1994-07-27
ATE109153T1 (de) 1994-08-15
DE69011033D1 (de) 1994-09-01
NO904372D0 (no) 1990-10-09
HU906389D0 (en) 1991-04-29
EP0422307A1 (en) 1991-04-17
IE64079B1 (en) 1995-07-12
CA2027276C (en) 2000-05-16
NO904372L (no) 1991-04-11
CN1050879A (zh) 1991-04-24
AU6375690A (en) 1991-04-18
IL95928A (en) 1994-08-26
DK0422975T3 (da) 1994-08-22
ZA907936B (en) 1991-08-28
NO174203C (no) 1994-04-06
IL95928A0 (en) 1991-07-18
HU209724B (en) 1994-10-28
TW225539B (cg-RX-API-DMAC10.html) 1994-06-21
DE69011033T2 (de) 1994-11-17
PT95547B (pt) 1998-02-27
EP0422975A1 (en) 1991-04-17
HUT55402A (en) 1991-05-28
FI101796B (fi) 1998-08-31
CN1029974C (zh) 1995-10-11
JP3032266B2 (ja) 2000-04-10

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