KE2923A - Novel penicillins and cephalosporine and process for producing the same - Google Patents

Novel penicillins and cephalosporine and process for producing the same

Info

Publication number
KE2923A
KE2923A KE2923A KE292379A KE2923A KE 2923 A KE2923 A KE 2923A KE 2923 A KE2923 A KE 2923A KE 292379 A KE292379 A KE 292379A KE 2923 A KE2923 A KE 2923A
Authority
KE
Kenya
Prior art keywords
cephalosporine
producing
same
amino acid
compound
Prior art date
Application number
KE2923A
Inventor
T Yasuda
O Takashima
Y Kodama
S Takano
S Kuroda
I Saikawa
K Momonoi
C Yoshida
M Komatsu
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP5066374A external-priority patent/JPS539238B2/ja
Priority claimed from JP5225474A external-priority patent/JPS539239B2/ja
Priority claimed from JP6078774A external-priority patent/JPS539240B2/ja
Priority claimed from JP9199674A external-priority patent/JPS5123284A/en
Priority claimed from JP10995474A external-priority patent/JPS5139687A/en
Priority claimed from JP14249974A external-priority patent/JPS5170788A/en
Priority claimed from JP50037207A external-priority patent/JPS51113890A/en
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of KE2923A publication Critical patent/KE2923A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

1508064 N-Piperazinocarbonyl-amino acid derivatives TOYAMA CHEMICAL CO Ltd 28 April 1975 [13 Aug 1974 28 Oct 1974 17 Feb 1975] 15360/77 Divided out of 1508062 Heading C2C Novel compounds I and salts and carboxyl derivatives thereof (R is an amino acid residue; R<SP>2</SP> and R<SP>3</SP> are H or alkyl and R<SP>2</SP> and R<SP>3</SP> are both linked to the same carbon atom; and A is H or an optionally substituted alkyl, alkenyl, aryl or aralkyl group) are prepared by reaction of a compound II NH 2 RCOOR<SP>1</SP> (III) (R<SP>1</SP> is H or a cation) with a reactive derivative of a compound IV
KE2923A 1974-05-09 1979-03-01 Novel penicillins and cephalosporine and process for producing the same KE2923A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP5066374A JPS539238B2 (en) 1974-05-09 1974-05-09
JP5225474A JPS539239B2 (en) 1974-05-13 1974-05-13
JP6078774A JPS539240B2 (en) 1974-05-31 1974-05-31
JP9199674A JPS5123284A (en) 1974-08-13 1974-08-13 Shinkina penishirinruino seizoho
JP10995474A JPS5139687A (en) 1974-09-26 1974-09-26 SHINKINAPENISHIRINRUINOSEIZOHO
JP14249974A JPS5170788A (en) 1974-12-13 1974-12-13 Shinkina sefuarosuhorinruino seizoho
JP50037207A JPS51113890A (en) 1975-03-27 1975-03-27 Method for preparing novel cephalosporins

Publications (1)

Publication Number Publication Date
KE2923A true KE2923A (en) 1979-04-06

Family

ID=27564446

Family Applications (1)

Application Number Title Priority Date Filing Date
KE2923A KE2923A (en) 1974-05-09 1979-03-01 Novel penicillins and cephalosporine and process for producing the same

Country Status (18)

Country Link
AR (1) AR209607A1 (en)
AT (1) AT344906B (en)
BE (1) BE828692A (en)
CH (1) CH605995A5 (en)
CY (1) CY1026A (en)
DD (1) DD117882A5 (en)
DE (2) DE2560239C2 (en)
DK (1) DK151338C (en)
FI (1) FI63760C (en)
FR (2) FR2269937B1 (en)
GB (2) GB1508062A (en)
HK (1) HK26279A (en)
HU (1) HU169633B (en)
IL (2) IL47168A (en)
KE (1) KE2923A (en)
NL (1) NL162386C (en)
PH (5) PH21545A (en)
SE (2) SE431457B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL49846A (en) * 1975-06-24 1979-07-25 Bayer Ag Penicillin and cephalosporin compounds containing an imidazolidinone ring substituted by a carbocycle or heterocycletheir preparation and pharmaceutical compositions comprising them
DE2528079A1 (en) * 1975-06-24 1977-01-20 Bayer Ag PENICILLIN, THE METHOD FOR MANUFACTURING IT AND THEIR USE AS A MEDICINAL PRODUCT
FR2338046A2 (en) * 1976-01-19 1977-08-12 Toyama Chemical Co Ltd Broad-spectrum cephalosporin antibiotics resistant to beta-lactamase - 7-(alpha-(4pethyl-2,3-dioxo-piperazinocarbonylamino)-para-hydroxy- phenylacetamido)-ceph-3-em-4-carboxylic acids
JPS6026800B2 (en) * 1976-01-22 1985-06-25 富山化学工業株式会社 Novel 7α-methoxycephalosporins and their production method
JPS52106883A (en) * 1976-02-13 1977-09-07 Toyama Chem Co Ltd Novel penicillins and cephalosporins
JPS5331690A (en) * 1976-09-01 1978-03-25 Shionogi & Co Ltd Oxadithiacephalosporins
DE2857696C2 (en) * 1977-07-23 1984-08-30 Toyama Chemical Co. Ltd., Tokio / Tokyo Cephalosporins
DE2810083A1 (en) * 1978-03-08 1979-09-20 Bayer Ag BETA-LACTAM COMPOUNDS
DE2813771A1 (en) * 1978-03-30 1979-10-11 Bayer Ag BETA-LACTAM COMPOUNDS
DE2817228A1 (en) * 1978-04-20 1979-10-31 Bayer Ag PROCESS FOR MANUFACTURING SEMI-SYNTHETIC BETA-LACTAMANTIBIOTICS
EP0015240A1 (en) * 1979-02-16 1980-09-03 Ciba-Geigy Ag Azacyclyl (thio) ureidoacetyl compounds and their preparation
CA1209477A (en) * 1981-03-26 1986-08-12 Bruce E. Haeger Composition of matter comprising a lyophilized preparation of a penicillin derivative
CA1200239A (en) * 1981-03-30 1986-02-04 Donald C. Boop Process for preparing 6-¬d-(-)-alpha-(4-c1-c4 alkyl- 2,3-dioxo-1-piperazinocarbonyl-amino)- phenylacetamido|penicillanic acid
JPS57118587A (en) * 1981-11-26 1982-07-23 Toyama Chem Co Ltd Novel penicillin
BG46664A1 (en) * 1985-08-16 1990-02-15 Druzhestven N Izsledovatelski Method for preparing of 6- /d (-)- alpha- (4- ethyl- 2, 3- dioxo- 1- piperazine carbonylamino)- phenylacetamido/- penicillanic acid
DE3619562A1 (en) * 1986-06-11 1987-12-17 Basf Ag METHOD FOR PRODUCING 2,3-DIOXO-4-OXICARBONYLPIPERAZINE DERIVATIVES, NEW 2,3-DIOXO-4-OXICARBONYLPIPERAZINE DERIVATIVES AND THE USE THEREOF
US5859012A (en) * 1996-04-03 1999-01-12 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
USRE39921E1 (en) 1999-10-07 2007-11-13 Smithkline Beecham Corporation Chemical compounds
GB9923748D0 (en) 1999-10-07 1999-12-08 Glaxo Group Ltd Chemical compounds
GB0025354D0 (en) 2000-10-17 2000-11-29 Glaxo Group Ltd Chemical compounds
EP2014291B1 (en) * 2001-08-24 2011-10-26 Yale University Piperazinone compounds as anti-tumor and anti-cancer agents
GB0203022D0 (en) 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
GB0203020D0 (en) 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
EP1472222A1 (en) 2002-02-08 2004-11-03 Glaxo Group Limited Piperidylcarboxamide derivatives and their use in the treatment of tachykinim-mediated diseases
MX2009008124A (en) * 2007-01-31 2009-10-08 Toyama Chemical Co Ltd Novel crystal of piperacillin sodium.
ME02666B (en) 2008-10-31 2017-06-20 Shionogi & Co Cephalosporin having catechol group
US8883773B2 (en) 2010-04-05 2014-11-11 Shionogi & Co., Ltd. Cephem compound having pseudo-catechol group
CA2795322A1 (en) 2010-04-05 2011-10-13 Shionogi & Co., Ltd. Cephem compound having catechol group
JP5852562B2 (en) 2010-04-28 2016-02-03 塩野義製薬株式会社 Novel cephem derivatives
CN103635478A (en) 2011-04-28 2014-03-12 盐野义制药株式会社 Novel cephem compound having catechol or pseudo-catechol structure
US9242999B2 (en) 2011-06-27 2016-01-26 Shionogi & Co., Ltd. Cephem compound having pyridinium group
CN110746445B (en) * 2019-10-16 2021-03-16 深圳海关食品检验检疫技术中心 Preparation method of cefoperazone deuterated internal standard substance

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1770620A1 (en) * 1968-06-12 1971-11-11 Bayer Ag New penicillins
DE2025415C3 (en) * 1970-05-25 1981-01-22 Bayer Ag, 5090 Leverkusen Process for the preparation of cyclic acylureido penicillins
DE2104580C3 (en) * 1971-02-01 1981-04-02 Bayer Ag, 5090 Leverkusen Acylureidopenicillins
US3741962A (en) 1971-05-21 1973-06-26 Squibb & Sons Inc Alpha-thioureidocephalosporanic acid compounds
BE790440A (en) * 1971-10-23 1973-04-24 Bayer Ag
BE794886A (en) * 1972-02-22 1973-08-02 Pfizer 6- (ALPHA- (OMEGA-GUANIDINOALCANOYLAMINO) ACYLAMINO) -PENICILLANIC ACIDS
CH570407A5 (en) * 1972-03-29 1975-12-15 Ciba Geigy Ag
AR204162A1 (en) * 1972-05-08 1975-11-28 Yamanouchi Pharma Co Ltd PROCESS FOR THE PREPARATION OF AMPICILLIN DERIVATIVES
AR208171A1 (en) 1972-09-29 1976-12-09 Ciba Geigy Ag PROCEDURE FOR OBTAINING NEW DERIVATIVES OF CEF-3-EM-4-CARBOXYL ACID

Also Published As

Publication number Publication date
FR2269937A1 (en) 1975-12-05
SE7505392L (en) 1975-12-23
HK26279A (en) 1979-05-04
NL162386B (en) 1979-12-17
AR209607A1 (en) 1977-05-13
GB1508062A (en) 1978-04-19
PH22336A (en) 1988-08-12
ATA828976A (en) 1977-12-15
SE7808204L (en) 1978-07-27
DK151338B (en) 1987-11-23
FI751340A (en) 1975-11-10
FR2320295B1 (en) 1980-11-07
IL53485A0 (en) 1978-01-31
DK151338C (en) 1988-07-18
GB1508064A (en) 1978-04-19
DE2519400C3 (en) 1982-02-11
BE828692A (en) 1975-11-03
IL47168A0 (en) 1975-06-25
PH20534A (en) 1987-02-09
AU8043175A (en) 1976-10-28
CH605995A5 (en) 1978-10-13
PH21545A (en) 1987-12-11
FI63760C (en) 1983-08-10
CY1026A (en) 1980-08-01
DK201975A (en) 1975-11-10
HU169633B (en) 1976-12-28
NL162386C (en) 1980-05-16
FR2320295A1 (en) 1977-03-04
SE431457B (en) 1984-02-06
IL47168A (en) 1979-07-25
DE2519400B2 (en) 1981-05-21
DE2560239C2 (en) 1984-10-11
FR2269937B1 (en) 1979-06-15
NL7505375A (en) 1975-11-11
SE435062B (en) 1984-09-03
DD117882A5 (en) 1976-02-05
FI63760B (en) 1983-04-29
DE2519400A1 (en) 1976-03-04
PH21987A (en) 1988-05-02
AT344906B (en) 1978-08-25
PH22346A (en) 1988-08-12

Similar Documents

Publication Publication Date Title
KE2923A (en) Novel penicillins and cephalosporine and process for producing the same
ES8401466A1 (en) Compounds, process for their preparation and their use as pharmaceutical preparations.
CA1238910A (en) Carboxyalkenoic acids
GB1488674A (en) Hypolipidemic 4-(monoalkylamino)benzoic acid derivatives
GB1433920A (en) Alkanolamine derivatives
GB1467604A (en) Bis-type penicillins and process for producing the same
JPS54128591A (en) Cephalosporin analog
ES454267A1 (en) Shinkina penishirinruino seizoho
GB1526038A (en) 5-thiazole methane amine derivatives and salts thereof processes for preparing them and pharmaceutical compositions containing them
GB1460427A (en) Phenothiazine derivatives
GB1501476A (en) Process for the preparation of reactive penicillanic acid and cephalosporanic acid derivatives and a process for the preparation thereof
ES8104309A1 (en) Process for preparing enamine derivatives, compounds so produced and process for preparing a 3-hydroxy-cephalosporin.
ATE18208T1 (en) N-(4-HYDROXYPHENYL)ACETIC ACID ESTERS FROM 5BENZOYL-1-METHYLPYRROL-2-ACETIC ACID.
GB1433595A (en) Alkanolamine derivatives
GB1512620A (en) Derivatives of dithiepino(1,4)(2,3-c)pyrrole
ES429691A1 (en) Preparation of p-isobutyl hydratropic acid and intermediates therefor
ES454265A1 (en) Method for preparing novel cephalosporins
GB1514306A (en) Eburnamenine derivatives and a process for the preparation thereof
ES386716A1 (en) Procedure for the preparation of new derivatives of tiepine. (Machine-translation by Google Translate, not legally binding)
ES398734A1 (en) Pentavalent phosphorus amides of cephalosporins
ES300123A1 (en) A procedure for the preparation of new derivatives of piperazine replaced asymmetrically (Machine-translation by Google Translate, not legally binding)
GB1441206A (en) Process for preparing 2-amino-4-hydroxypyrimidine derivatives
GB1525549A (en) Substituted quinoline derivatives
GB1452205A (en) Process of preparing cephalosporanic acid esters derivatives
ES473484A1 (en) A procedure for the preparation of new eteres of the clavulan acid (Machine-translation by Google Translate, not legally binding)