PH21987A - Process for producing novel penicillins and cephalosporins - Google Patents

Process for producing novel penicillins and cephalosporins

Info

Publication number
PH21987A
PH21987A PH19814A PH19814A PH21987A PH 21987 A PH21987 A PH 21987A PH 19814 A PH19814 A PH 19814A PH 19814 A PH19814 A PH 19814A PH 21987 A PH21987 A PH 21987A
Authority
PH
Philippines
Prior art keywords
cephalosporins
amino acid
compound
producing novel
novel penicillins
Prior art date
Application number
PH19814A
Inventor
Isamu Saikawa
Shuntaro Takano
Okuta Takashima
Seietsu Kuroda
Yutaka Kodama
Chosaku Yoshida
Kaishu Momonoi
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP5066374A external-priority patent/JPS539238B2/ja
Priority claimed from JP5225474A external-priority patent/JPS539239B2/ja
Priority claimed from JP6078774A external-priority patent/JPS539240B2/ja
Priority claimed from JP9199674A external-priority patent/JPS5123284A/en
Priority claimed from JP10995474A external-priority patent/JPS5139687A/en
Priority claimed from JP14249974A external-priority patent/JPS5170788A/en
Priority claimed from JP50037207A external-priority patent/JPS51113890A/en
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of PH21987A publication Critical patent/PH21987A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

1508064 N-Piperazinocarbonyl-amino acid derivatives TOYAMA CHEMICAL CO Ltd 28 April 1975 [13 Aug 1974 28 Oct 1974 17 Feb 1975] 15360/77 Divided out of 1508062 Heading C2C Novel compounds I and salts and carboxyl derivatives thereof (R is an amino acid residue; R<SP>2</SP> and R<SP>3</SP> are H or alkyl and R<SP>2</SP> and R<SP>3</SP> are both linked to the same carbon atom; and A is H or an optionally substituted alkyl, alkenyl, aryl or aralkyl group) are prepared by reaction of a compound II NH 2 RCOOR<SP>1</SP> (III) (R<SP>1</SP> is H or a cation) with a reactive derivative of a compound IV
PH19814A 1974-05-09 1977-05-25 Process for producing novel penicillins and cephalosporins PH21987A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP5066374A JPS539238B2 (en) 1974-05-09 1974-05-09
JP5225474A JPS539239B2 (en) 1974-05-13 1974-05-13
JP6078774A JPS539240B2 (en) 1974-05-31 1974-05-31
JP9199674A JPS5123284A (en) 1974-08-13 1974-08-13 Shinkina penishirinruino seizoho
JP10995474A JPS5139687A (en) 1974-09-26 1974-09-26 SHINKINAPENISHIRINRUINOSEIZOHO
JP14249974A JPS5170788A (en) 1974-12-13 1974-12-13 Shinkina sefuarosuhorinruino seizoho
JP50037207A JPS51113890A (en) 1975-03-27 1975-03-27 Method for preparing novel cephalosporins

Publications (1)

Publication Number Publication Date
PH21987A true PH21987A (en) 1988-05-02

Family

ID=27564446

Family Applications (5)

Application Number Title Priority Date Filing Date
PH17137A PH21545A (en) 1974-05-09 1975-05-05 Novel penicillins and pharmaceutically acceptable salts thereof which contain a mono- or di- oxo piperazino (thio)-carbonyl amino group in molecule
PH18076A PH20534A (en) 1974-05-09 1976-02-10 Novel cephalosporins having a mono or d-oxo-piperazino-carbonyl groups in the molecule and a pharmaceutical composition thereof
PH19129A PH22336A (en) 1974-05-09 1976-11-15 A reactive derivative of 2,3-dioxapiperazine derivative
PH19128A PH22346A (en) 1974-05-09 1976-11-15 2,3-dioxo-piperazino carbonylamino alkanoic acid
PH19814A PH21987A (en) 1974-05-09 1977-05-25 Process for producing novel penicillins and cephalosporins

Family Applications Before (4)

Application Number Title Priority Date Filing Date
PH17137A PH21545A (en) 1974-05-09 1975-05-05 Novel penicillins and pharmaceutically acceptable salts thereof which contain a mono- or di- oxo piperazino (thio)-carbonyl amino group in molecule
PH18076A PH20534A (en) 1974-05-09 1976-02-10 Novel cephalosporins having a mono or d-oxo-piperazino-carbonyl groups in the molecule and a pharmaceutical composition thereof
PH19129A PH22336A (en) 1974-05-09 1976-11-15 A reactive derivative of 2,3-dioxapiperazine derivative
PH19128A PH22346A (en) 1974-05-09 1976-11-15 2,3-dioxo-piperazino carbonylamino alkanoic acid

Country Status (18)

Country Link
AR (1) AR209607A1 (en)
AT (1) AT344906B (en)
BE (1) BE828692A (en)
CH (1) CH605995A5 (en)
CY (1) CY1026A (en)
DD (1) DD117882A5 (en)
DE (2) DE2560239C2 (en)
DK (1) DK151338C (en)
FI (1) FI63760C (en)
FR (2) FR2269937B1 (en)
GB (2) GB1508062A (en)
HK (1) HK26279A (en)
HU (1) HU169633B (en)
IL (2) IL47168A (en)
KE (1) KE2923A (en)
NL (1) NL162386C (en)
PH (5) PH21545A (en)
SE (2) SE431457B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL49846A (en) * 1975-06-24 1979-07-25 Bayer Ag Penicillin and cephalosporin compounds containing an imidazolidinone ring substituted by a carbocycle or heterocycletheir preparation and pharmaceutical compositions comprising them
DE2528079A1 (en) * 1975-06-24 1977-01-20 Bayer Ag PENICILLIN, THE METHOD FOR MANUFACTURING IT AND THEIR USE AS A MEDICINAL PRODUCT
FR2338046A2 (en) * 1976-01-19 1977-08-12 Toyama Chemical Co Ltd Broad-spectrum cephalosporin antibiotics resistant to beta-lactamase - 7-(alpha-(4pethyl-2,3-dioxo-piperazinocarbonylamino)-para-hydroxy- phenylacetamido)-ceph-3-em-4-carboxylic acids
JPS6026800B2 (en) * 1976-01-22 1985-06-25 富山化学工業株式会社 Novel 7α-methoxycephalosporins and their production method
JPS52106883A (en) * 1976-02-13 1977-09-07 Toyama Chem Co Ltd Novel penicillins and cephalosporins
JPS5331690A (en) * 1976-09-01 1978-03-25 Shionogi & Co Ltd Oxadithiacephalosporins
DE2857696C2 (en) * 1977-07-23 1984-08-30 Toyama Chemical Co. Ltd., Tokio / Tokyo Cephalosporins
DE2810083A1 (en) * 1978-03-08 1979-09-20 Bayer Ag BETA-LACTAM COMPOUNDS
DE2813771A1 (en) * 1978-03-30 1979-10-11 Bayer Ag BETA-LACTAM COMPOUNDS
DE2817228A1 (en) * 1978-04-20 1979-10-31 Bayer Ag PROCESS FOR MANUFACTURING SEMI-SYNTHETIC BETA-LACTAMANTIBIOTICS
EP0015240A1 (en) * 1979-02-16 1980-09-03 Ciba-Geigy Ag Azacyclyl (thio) ureidoacetyl compounds and their preparation
CA1209477A (en) * 1981-03-26 1986-08-12 Bruce E. Haeger Composition of matter comprising a lyophilized preparation of a penicillin derivative
CA1200239A (en) * 1981-03-30 1986-02-04 Donald C. Boop Process for preparing 6-¬d-(-)-alpha-(4-c1-c4 alkyl- 2,3-dioxo-1-piperazinocarbonyl-amino)- phenylacetamido|penicillanic acid
JPS57118587A (en) * 1981-11-26 1982-07-23 Toyama Chem Co Ltd Novel penicillin
BG46664A1 (en) * 1985-08-16 1990-02-15 Druzhestven N Izsledovatelski Method for preparing of 6- /d (-)- alpha- (4- ethyl- 2, 3- dioxo- 1- piperazine carbonylamino)- phenylacetamido/- penicillanic acid
DE3619562A1 (en) * 1986-06-11 1987-12-17 Basf Ag METHOD FOR PRODUCING 2,3-DIOXO-4-OXICARBONYLPIPERAZINE DERIVATIVES, NEW 2,3-DIOXO-4-OXICARBONYLPIPERAZINE DERIVATIVES AND THE USE THEREOF
US5859012A (en) * 1996-04-03 1999-01-12 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
USRE39921E1 (en) 1999-10-07 2007-11-13 Smithkline Beecham Corporation Chemical compounds
GB9923748D0 (en) 1999-10-07 1999-12-08 Glaxo Group Ltd Chemical compounds
GB0025354D0 (en) 2000-10-17 2000-11-29 Glaxo Group Ltd Chemical compounds
CA2458009C (en) * 2001-08-24 2011-08-16 Yale University Piperazinone compounds as anti-tumor and anti-cancer agents and methods of treatment
GB0203020D0 (en) 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
US7482365B2 (en) 2002-02-08 2009-01-27 Glaxo Group Limited Piperidylcarboxamide derivatives and their use in the treatment of tachykinin-mediated diseases
GB0203022D0 (en) 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
KR20090104855A (en) * 2007-01-31 2009-10-06 토야마 케미칼 컴퍼니 리미티드 Novel crystal of piperacillin sodium
ME02666B (en) 2008-10-31 2017-06-20 Shionogi & Co Cephalosporin having catechol group
AU2011236933A1 (en) 2010-04-05 2013-05-02 Shionogi & Co., Ltd. Cephem compound having catechol group
JP5852559B2 (en) 2010-04-05 2016-02-03 塩野義製薬株式会社 Cephem compounds having pseudo-catechol groups
JP5852562B2 (en) 2010-04-28 2016-02-03 塩野義製薬株式会社 Novel cephem derivatives
JP6006201B2 (en) 2011-04-28 2016-10-12 塩野義製薬株式会社 Novel cephem compounds having catechol or pseudo-catechol structure
CN103619853A (en) 2011-06-27 2014-03-05 盐野义制药株式会社 Cephem compound having pyridinium group
CN110746445B (en) * 2019-10-16 2021-03-16 深圳海关食品检验检疫技术中心 Preparation method of cefoperazone deuterated internal standard substance

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1770620A1 (en) * 1968-06-12 1971-11-11 Bayer Ag New penicillins
DE2104580C3 (en) * 1971-02-01 1981-04-02 Bayer Ag, 5090 Leverkusen Acylureidopenicillins
DE2025415C3 (en) * 1970-05-25 1981-01-22 Bayer Ag, 5090 Leverkusen Process for the preparation of cyclic acylureido penicillins
US3741962A (en) 1971-05-21 1973-06-26 Squibb & Sons Inc Alpha-thioureidocephalosporanic acid compounds
BE790440A (en) * 1971-10-23 1973-04-24 Bayer Ag
BE794886A (en) * 1972-02-22 1973-08-02 Pfizer 6- (ALPHA- (OMEGA-GUANIDINOALCANOYLAMINO) ACYLAMINO) -PENICILLANIC ACIDS
CH570407A5 (en) * 1972-03-29 1975-12-15 Ciba Geigy Ag
AR204813A1 (en) * 1972-05-08 1976-03-05 Yamanouchi Pharma Co Ltd PROCESS FOR THE PREPARATION OF AMPYLICIN DERIVATIVES
AR208171A1 (en) 1972-09-29 1976-12-09 Ciba Geigy Ag PROCEDURE FOR OBTAINING NEW DERIVATIVES OF CEF-3-EM-4-CARBOXYL ACID

Also Published As

Publication number Publication date
DD117882A5 (en) 1976-02-05
AR209607A1 (en) 1977-05-13
FI63760B (en) 1983-04-29
FR2320295A1 (en) 1977-03-04
KE2923A (en) 1979-04-06
DK151338B (en) 1987-11-23
PH22346A (en) 1988-08-12
CY1026A (en) 1980-08-01
DE2560239C2 (en) 1984-10-11
NL162386B (en) 1979-12-17
GB1508064A (en) 1978-04-19
SE7808204L (en) 1978-07-27
FR2320295B1 (en) 1980-11-07
IL47168A0 (en) 1975-06-25
ATA828976A (en) 1977-12-15
FR2269937A1 (en) 1975-12-05
AU8043175A (en) 1976-10-28
DK151338C (en) 1988-07-18
FI63760C (en) 1983-08-10
DE2519400A1 (en) 1976-03-04
FR2269937B1 (en) 1979-06-15
HK26279A (en) 1979-05-04
BE828692A (en) 1975-11-03
NL7505375A (en) 1975-11-11
PH22336A (en) 1988-08-12
DK201975A (en) 1975-11-10
DE2519400B2 (en) 1981-05-21
GB1508062A (en) 1978-04-19
NL162386C (en) 1980-05-16
SE7505392L (en) 1975-12-23
DE2519400C3 (en) 1982-02-11
SE431457B (en) 1984-02-06
AT344906B (en) 1978-08-25
IL53485A0 (en) 1978-01-31
PH21545A (en) 1987-12-11
FI751340A (en) 1975-11-10
IL47168A (en) 1979-07-25
SE435062B (en) 1984-09-03
PH20534A (en) 1987-02-09
HU169633B (en) 1976-12-28
CH605995A5 (en) 1978-10-13

Similar Documents

Publication Publication Date Title
PH21987A (en) Process for producing novel penicillins and cephalosporins
DE3363244D1 (en) Compounds, process for their preparation and their use as pharmaceutical preparations
GB1488674A (en) Hypolipidemic 4-(monoalkylamino)benzoic acid derivatives
CA1238910A (en) Carboxyalkenoic acids
ES412859A1 (en) Process for preparing 7-(alpha-hydroxy-alpha-phenyl)acetamido-3-(1-methyl-1h-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and derivatives thereof
GB1467604A (en) Bis-type penicillins and process for producing the same
JPS54128591A (en) Cephalosporin analog
ES385437A1 (en) Method for the preparation of new derivatives of penicilanico acid. (Machine-translation by Google Translate, not legally binding)
ES454267A1 (en) Shinkina penishirinruino seizoho
GB1460427A (en) Phenothiazine derivatives
GB1501476A (en) Process for the preparation of reactive penicillanic acid and cephalosporanic acid derivatives and a process for the preparation thereof
ES8200092A1 (en) Esters of N-(4&#39;-hydroxyphenyl)acetamide with 5-benzoyl-1-methylpyrrole-2-acetic acids.
GB1446701A (en) Vincamine 2-ketoglutarate and process for the production thereof
ES8104309A1 (en) Process for preparing enamine derivatives, compounds so produced and process for preparing a 3-hydroxy-cephalosporin.
ES454265A1 (en) Method for preparing novel cephalosporins
GB1433595A (en) Alkanolamine derivatives
GB1502689A (en) Substituted indanyl propionic acids
GB1514306A (en) Eburnamenine derivatives and a process for the preparation thereof
ES386716A1 (en) Procedure for the preparation of new derivatives of tiepine. (Machine-translation by Google Translate, not legally binding)
GB1441206A (en) Process for preparing 2-amino-4-hydroxypyrimidine derivatives
GB1382736A (en) Process of producing semi-synthetic penicillin
ES398734A1 (en) Pentavalent phosphorus amides of cephalosporins
ES8106281A1 (en) Preparation of aminosulphonic acids and their derivatives.
ES482419A1 (en) A procedure for the preparation of eteres of the acid - clavulanic. (Machine-translation by Google Translate, not legally binding)
ES300123A1 (en) A procedure for the preparation of new derivatives of piperazine replaced asymmetrically (Machine-translation by Google Translate, not legally binding)