ES473484A1 - A procedure for the preparation of new eteres of the clavulan acid (Machine-translation by Google Translate, not legally binding)
- Google Patents
A procedure for the preparation of new eteres of the clavulan acid (Machine-translation by Google Translate, not legally binding)
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Beecham Group PLC
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Beecham Group PLC
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Publication of ES473484A1publicationCriticalpatent/ES473484A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
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Abstract
A process for the preparation of new clavulanic acid ethers of formula (I) ** formula ** or a salt or ester thereof where R1 is a hydrogen atom or a lower alkyl, aryl or aralkyl group, R2 and R3 are independently hydrogen or a lower alkyl, aryl or aralkyl group R2 and R3 are independently hydrogen, aryl, aralkyl, lower alkyl or substituted alkyl, or R3 binds to R1 to form a 4, 5 or 6-membered ring or binds to R2 to forming a 5- or 6-membered ring, the process of which comprises a) reacting an ester of clavulanic acid with a compound of the formula (XV) Y-CHR1-NR-CO-R3 where R1, R2 and R3 are those defined with relative to formula (I) and Y is a movable group, b) optionally converting the ester thus formed into the free acid or salt thereof (Machine-translation by Google Translate, not legally binding)
ES473484A1977-09-201978-09-19A procedure for the preparation of new eteres of the clavulan acid (Machine-translation by Google Translate, not legally binding)
ExpiredES473484A1
(en)
A procedure for the preparation of new derivatives of a hydroxyamino hydrocarburophosphonic acid. (Machine-translation by Google Translate, not legally binding)
Procedure for the preparation of a separable mixture den-1 and N-2 glicosil-benz (f) indazol-4,9-dionas. (Machine-translation by Google Translate, not legally binding)