|
US2485614A
(en)
|
1946-08-29 |
1949-10-25 |
Chicago Bridge & Iron Co |
Stabilizing and guide apparatus for lifter roofs
|
|
US3037116A
(en)
|
1957-07-26 |
1962-05-29 |
Weber Georges |
Apparatus for irradiating liquids
|
|
US3035516A
(en)
|
1958-08-18 |
1962-05-22 |
Lee Brothers Company |
Stencil device
|
|
US3646509A
(en)
|
1969-08-08 |
1972-02-29 |
Texas Instruments Inc |
Method for field stacking seismic data and system using write after read bulk data storage
|
|
US4306075A
(en)
|
1980-03-28 |
1981-12-15 |
The Upjohn Company |
Composition and process
|
|
US4547016A
(en)
|
1984-08-13 |
1985-10-15 |
Eeco Incorporated |
Quick release mounting
|
|
GB8814438D0
(en)
|
1988-06-17 |
1988-07-20 |
Wellcome Found |
Compounds for use in medicine
|
|
IT1231076B
(it)
|
1989-09-28 |
1991-11-12 |
Pirelli Cavi Spa |
Procedimento per la realizzazione di gruppo di connessione separabile per fibre ottiche riunite a nastro e gruppo di connessione con esso realizzato.
|
|
GB9011588D0
(en)
|
1990-05-24 |
1990-07-11 |
Wellcome Found |
Prostaglandin analogues for use in medicine
|
|
US6441245B1
(en)
|
1997-10-24 |
2002-08-27 |
United Therapeutics Corporation |
Process for stereoselective synthesis of prostacyclin derivatives
|
|
EP1045695B1
(en)
|
1997-11-14 |
2004-03-24 |
United Therapeutics Corporation |
Use of 9-deoxy-2', 9-alpha-methano-3- oxa-4,5,6- trinor-3, 7-(1',3'-interphenylene) -13,14-dihydro- prostaglandin f 1? to treat peripheral vascular disease
|
|
US6521212B1
(en)
|
1999-03-18 |
2003-02-18 |
United Therapeutics Corporation |
Method for treating peripheral vascular disease by administering benzindene prostaglandins by inhalation
|
|
CN1354622A
(zh)
|
1999-03-31 |
2002-06-19 |
联合治疗公司 |
前列腺素类化合物、组合物和治疗外周血管疾病和肺动脉高压的方法
|
|
US6700025B2
(en)
|
2001-01-05 |
2004-03-02 |
United Therapeutics Corporation |
Process for stereoselective synthesis of prostacyclin derivatives
|
|
US6803386B2
(en)
|
2002-01-16 |
2004-10-12 |
United Therapeutics Corporation |
Prostacyclin derivative containing compositions and methods of using the same for the treatment of cancer
|
|
US6756117B1
(en)
|
2002-12-20 |
2004-06-29 |
The United States Of America As Represented By The United States Department Of Energy |
Photonic polymer-blend structures and method for making
|
|
CN101265226B
(zh)
|
2003-05-22 |
2013-04-24 |
联合治疗公司 |
化合物和释放前列环素类似物的方法
|
|
CN1917866B
(zh)
|
2003-12-16 |
2010-12-15 |
联合治疗公司 |
曲前列环素或它的衍生物，或其药学上可接受的盐在制备治疗和预防缺血性损害的药物中的用途
|
|
US20090124697A1
(en)
|
2003-12-16 |
2009-05-14 |
United Therapeutics Corporation |
Inhalation formulations of treprostinil
|
|
CA2549801C
(en)
|
2003-12-16 |
2012-10-16 |
United Therapeutics Corporation |
Use of treprostinil to improve kidney functions
|
|
ATE462427T1
(de)
|
2004-04-12 |
2010-04-15 |
United Therapeutics Corp |
Verwendung von treprostinil zur behandlung von neuropathischen diabetischen fussgeschwüren
|
|
US8747897B2
(en)
|
2006-04-27 |
2014-06-10 |
Supernus Pharmaceuticals, Inc. |
Osmotic drug delivery system
|
|
CN101495122B
(zh)
|
2006-05-15 |
2011-10-05 |
联合治疗公司 |
使用定量吸入器给予曲前列尼
|
|
US20090036465A1
(en)
|
2006-10-18 |
2009-02-05 |
United Therapeutics Corporation |
Combination therapy for pulmonary arterial hypertension
|
|
CA2678258A1
(en)
|
2007-02-09 |
2008-08-14 |
United Therapeutics Corporation |
Treprostinil treatment for interstitial lung disease and asthma
|
|
CA2698721A1
(en)
|
2007-09-07 |
2009-03-12 |
United Therapeutics Corporation |
Buffer solutions having selective bactericidal activity against gram negative bacteria and methods of using same
|
|
KR20160048222A
(ko)
|
2007-12-17 |
2016-05-03 |
유나이티드 세러퓨틱스 코오포레이션 |
레모둘린?의 활성 성분인 트레프로스티닐의 개선된 제조 방법
|
|
US8350079B2
(en)
|
2008-05-08 |
2013-01-08 |
United Therapeutics Corporation |
Treprostinil formulation
|
|
JP5649645B2
(ja)
|
2009-05-07 |
2015-01-07 |
ユナイテッド セラピューティクス コーポレイション |
プロスタサイクリンアナログの固形製剤
|
|
RS53234B
(sr)
|
2009-08-07 |
2014-08-29 |
Scipharm Sàrl |
Kompozicija za lečenje cistične fibroze
|
|
EP3108888B1
(en)
|
2010-03-15 |
2020-02-12 |
United Therapeutics Corporation |
Treatment for pulmonary hypertension
|
|
WO2011153363A1
(en)
|
2010-06-03 |
2011-12-08 |
United Therapeutics Corporation |
Treprostinil production
|
|
WO2012006273A1
(en)
*
|
2010-07-09 |
2012-01-12 |
United Therapeutics Corporation |
Combination therapies with cox-2 inhibitors and treprostinil
|
|
CA2710725C
(en)
|
2010-07-22 |
2017-08-01 |
Alphora Research Inc. |
Protected aldehydes for use as intermediates in chemical syntheses, and processes for their preparation
|
|
CA2710726C
(en)
|
2010-07-22 |
2016-02-23 |
Alphora Research Inc. |
Synthesis of treprostinil and intermediates useful therein
|
|
CA2726599C
(en)
|
2010-12-30 |
2017-07-25 |
Alphora Research Inc. |
Process for treprostinil salt preparation
|
|
EP2681204B1
(en)
|
2011-03-02 |
2016-04-27 |
United Therapeutics Corporation |
Synthesis of intermediate for treprostinil production
|
|
US9388154B2
(en)
|
2011-09-12 |
2016-07-12 |
Lund Biotechnology PBC |
Process for preparing synthetic prostacyclins
|
|
CN103193626B
(zh)
|
2012-01-10 |
2016-05-11 |
上海天伟生物制药有限公司 |
一种前列腺素类似物的晶型及其制备方法和用途
|
|
CN103193627B
(zh)
|
2012-01-10 |
2016-04-20 |
上海天伟生物制药有限公司 |
一种前列腺素类似物的晶型及其制备方法和用途
|
|
US9387214B2
(en)
|
2012-01-13 |
2016-07-12 |
United Therapeutics Corporation |
Method of identifying therapies for pulmonary hypertension
|
|
PL2674413T3
(pl)
|
2012-06-15 |
2018-05-30 |
Scipharm Sàrl |
Sposób wytwarzania treprostynilu i jego pochodnych
|
|
AU2013351934B2
(en)
|
2012-11-30 |
2018-03-29 |
Insmed Incorporated |
Prostacylin compositions and methods for using the same
|
|
CN104837806A
(zh)
|
2012-12-07 |
2015-08-12 |
开曼化学股份有限公司 |
前列环素类似物的合成方法
|
|
US9505737B2
(en)
|
2013-01-11 |
2016-11-29 |
Corsair Pharma, Inc. |
Treprostinil derivative compounds and methods of using same
|
|
EP3712142B1
(en)
|
2013-01-11 |
2022-07-06 |
Corsair Pharma, Inc. |
Prodrugs of treprostinil
|
|
EP2970091A4
(en)
|
2013-03-14 |
2017-02-08 |
United Therapeutics Corporation |
Solid forms of treprostinil
|
|
US20140275616A1
(en)
|
2013-03-15 |
2014-09-18 |
United Therapeutics Corporation |
Salts of treprostinil
|
|
CN105407883A
(zh)
|
2013-04-30 |
2016-03-16 |
联合治疗学有限公司 |
控释药物制剂
|
|
LT3060041T
(lt)
|
2013-10-25 |
2021-03-25 |
Insmed Incorporated |
Prostaciklino junginiai
|
|
TWI685348B
(zh)
|
2014-05-08 |
2020-02-21 |
美國禮來大藥廠 |
速效胰島素組合物
|
|
WO2015174197A1
(ja)
|
2014-05-14 |
2015-11-19 |
富士電機株式会社 |
半導体装置および半導体装置の製造方法
|
|
CN106573066A
(zh)
|
2014-06-13 |
2017-04-19 |
联合治疗学有限公司 |
曲前列环素制剂
|
|
US20160045470A1
(en)
|
2014-08-12 |
2016-02-18 |
Dr. Reddy's Laboratories Limited |
Amorphous solid dispersion of treprostinil diethanolamine
|
|
WO2016038532A1
(en)
|
2014-09-09 |
2016-03-17 |
Mylan Laboratories Limited |
Amorphous treprostinil diethanolamine
|
|
HU231184B1
(hu)
|
2014-10-08 |
2021-07-28 |
CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. |
Treprostinil-nátrium-monohidrát és eljárás ennek előállítására
|
|
ES2778274T3
(es)
|
2014-10-20 |
2020-08-10 |
United Therapeutics Corp |
Síntesis de productos intermedios para producir derivados de prostaciclina
|
|
JP6866043B2
(ja)
*
|
2014-11-18 |
2021-04-28 |
インスメッド インコーポレイテッド |
トレプロスチニルプロドラッグおよびトレプロスチニル誘導体プロドラッグの製造方法
|
|
TWI540121B
(zh)
|
2014-12-01 |
2016-07-01 |
臺灣永光化學工業股份有限公司 |
曲前列環素二乙醇胺之合成方法及新穎中間體
|
|
US10837038B2
(en)
|
2014-12-23 |
2020-11-17 |
National Technology & Engineering Solutions Of Sandia, Llc |
Adjusting the pH of a pretreatment solution using carbon dioxide useful for integrating saccharification and fermentation
|
|
US9394227B1
(en)
|
2015-06-17 |
2016-07-19 |
Corsair Pharma, Inc. |
Treprostinil derivatives and compositions and uses thereof
|
|
US9643911B2
(en)
*
|
2015-06-17 |
2017-05-09 |
Corsair Pharma, Inc. |
Treprostinil derivatives and compositions and uses thereof
|
|
JP7220650B2
(ja)
*
|
2016-09-26 |
2023-02-10 |
ユナイテッド セラピューティクス コーポレイション |
トレプロスチニルプロドラッグ
|
|
JP2022546314A
(ja)
*
|
2019-08-23 |
2022-11-04 |
ユナイテッド セラピューティクス コーポレイション |
トレプロスチニルプロドラッグ
|
|
WO2022132655A1
(en)
*
|
2020-12-14 |
2022-06-23 |
United Therapeutics Corporation |
Methods of treating disease with treprostinil prodrugs
|