|
US5595756A
(en)
|
1993-12-22 |
1997-01-21 |
Inex Pharmaceuticals Corporation |
Liposomal compositions for enhanced retention of bioactive agents
|
|
US6455677B1
(en)
|
1998-04-30 |
2002-09-24 |
Boehringer Ingelheim International Gmbh |
FAPα-specific antibody with improved producibility
|
|
US6465181B2
(en)
|
1999-03-25 |
2002-10-15 |
Abbott Laboratories |
Reagents and methods useful for detecting diseases of the prostate
|
|
ES2275513T3
(es)
|
1999-05-17 |
2007-06-16 |
Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Und Zum Vertrieb Von Pharmaka Mbh |
Propiedades neuroprotectoras de gdf-15, un miembro de la superfamilia de tgf-beta.
|
|
US7141661B2
(en)
|
2000-09-08 |
2006-11-28 |
The United States Of America As Represented By The Department Of Health And Human Services |
Non-steroidal anti-inflammatory drug activated gene with anti-tumorigenic properties
|
|
DK2311873T3
(en)
|
2004-01-07 |
2018-11-26 |
Novartis Vaccines & Diagnostics Inc |
M-CSF-SPECIFIC MONOCLONAL ANTIBODY AND APPLICATIONS THEREOF
|
|
EP1734986B1
(en)
|
2004-04-13 |
2015-11-11 |
St Vincent's Hospital Sydney Limited |
Method for modulating appetite
|
|
WO2007067500A2
(en)
|
2005-12-05 |
2007-06-14 |
Genomic Health, Inc. |
Predictors of patient response to treatment with egfr inhibitors
|
|
US20100278843A1
(en)
|
2007-08-16 |
2010-11-04 |
St. Vincent's Hospital Sydney Limited |
Agents and methods for modulating macrophage inhibitory cytokine (mic-1) activity
|
|
US20100266707A1
(en)
|
2007-10-09 |
2010-10-21 |
Samuel Norbert Breit |
Method of treating cachexia with the removal or inactivation of macrophage inhibitory cytokine-1
|
|
WO2009150255A2
(en)
|
2008-06-13 |
2009-12-17 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Markers for predicting response and survival in anti-egfr treated patients
|
|
JP5581323B2
(ja)
|
2008-09-29 |
2014-08-27 |
ロシュ グリクアート アクチェンゲゼルシャフト |
ヒトｉｌ１７に対する抗体およびその使用
|
|
US8476410B2
(en)
|
2008-10-16 |
2013-07-02 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Fully human antibodies to high molecular weight-melanoma associated antigen and uses thereof
|
|
EP2209003A1
(en)
|
2009-01-16 |
2010-07-21 |
F. Hoffmann-Roche AG |
Means and methods for differentiating between fibrosis and cirrhosis
|
|
US7736861B1
(en)
|
2009-10-19 |
2010-06-15 |
Aveo Pharmaceuticals, Inc. |
Tivozanib response prediction
|
|
WO2011050407A1
(en)
|
2009-10-28 |
2011-05-05 |
St Vincent's Hospital Sydney Limited |
Methods of diagnosing and prognosing colonic polyps
|
|
US9212221B2
(en)
|
2010-03-03 |
2015-12-15 |
Detroit R & D, Inc. |
Form-specific antibodies for NAG-1 (MIC-1, GDF-15), H6D and other TGF-β subfamily and heart disease and cancer diagnoses
|
|
WO2011127219A1
(en)
|
2010-04-06 |
2011-10-13 |
Caris Life Sciences Luxembourg Holdings |
Circulating biomarkers for disease
|
|
EP2388594A1
(en)
|
2010-05-17 |
2011-11-23 |
Roche Diagnostics GmbH |
GDF-15 based means and methods for survival and recovery prediction in acute inflammation
|
|
PH12016502073B1
(en)
|
2010-11-17 |
2024-04-05 |
Chugai Pharmaceutical Co Ltd |
Multi-specific antigen-binding molecule having alternative function to function of blood coagulation factor viii
|
|
EP2506015A1
(en)
|
2011-04-01 |
2012-10-03 |
Universität Regensburg |
A prognostic and therapeutic signature for malignant melanoma
|
|
EP2714738B1
(en)
|
2011-05-24 |
2018-10-10 |
Zyngenia, Inc. |
Multivalent and monovalent multispecific complexes and their uses
|
|
WO2013012648A1
(en)
|
2011-07-15 |
2013-01-24 |
Emory University |
Gdf15 in diagnostic and therapeutic applications
|
|
US8790651B2
(en)
|
2011-07-21 |
2014-07-29 |
Zoetis Llc |
Interleukin-31 monoclonal antibody
|
|
CN102321173B
(zh)
|
2011-08-12 |
2013-04-03 |
中国医学科学院肿瘤研究所 |
人源化巨噬细胞抑制因子1单克隆抗体及其应用
|
|
EP2565262A1
(en)
|
2011-08-31 |
2013-03-06 |
VTU Holding GmbH |
Protein expression
|
|
JP2015506373A
(ja)
|
2012-01-26 |
2015-03-02 |
アムジエン・インコーポレーテツド |
成長分化因子１５（ｇｄｆ−１５）ポリペプチド
|
|
HRP20191326T1
(hr)
|
2012-09-26 |
2019-11-01 |
Univ Wuerzburg J Maximilians |
Monoklonska antitijela za faktor rasta i diferencijacije 15 (gdf-15)
|
|
CA2896076C
(en)
|
2012-12-21 |
2022-12-06 |
Aveo Pharmaceuticals, Inc. |
Anti-gdf15 antibodies
|
|
WO2014151026A1
(en)
|
2013-03-15 |
2014-09-25 |
Myriad Genetics, Inc. |
Genes and gene signatures for diagnosis and treatment of melanoma
|
|
CA2935804A1
(en)
|
2014-01-14 |
2015-07-23 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for identification, assessment, prevention, and treatment of melanoma using pd-l1 isoforms
|
|
EP3470848A3
(en)
|
2014-01-28 |
2019-05-22 |
Roche Diagnostics GmbH |
Biomarkers for risk assessment and treatment monitoring in heart failure patients guided by natriuretic peptides
|
|
MX385194B
(es)
|
2014-02-21 |
2025-03-14 |
Nektar Therapeutics India Pvt Ltd |
Agonistas il-2rbeta-selectivos en combinación con un anticuerpo anti-ctla-4 o un anticuerpo anti-pd-1.
|
|
LT3653644T
(lt)
|
2014-03-26 |
2024-01-25 |
Julius-Maximilians-Universität Würzburg |
Monokloniniai antikūnai prieš augimo ir diferenciacijos faktorių 15 (gdf- 15), ir jų panaudojimas taikant vėžio kacheksijos ir vėžio gydymą
|
|
EP3197493B1
(en)
*
|
2014-09-25 |
2021-03-10 |
Aveo Pharmaceuticals Inc. |
Methods of reversing cachexia and prolonging survival comprising administering a gdf15 modulator and an anti-cancer agent
|
|
EP3073268A1
(en)
|
2015-03-27 |
2016-09-28 |
Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts |
Biomarker panel for diagnosing cancer
|
|
CN108463246B
(zh)
|
2015-10-02 |
2025-02-28 |
尤利乌斯·马克西米利安维尔茨堡大学 |
使用人生长分化因子15(gdf-15)抑制剂和免疫检查点阻断剂的联合治疗
|
|
GB201517528D0
(en)
|
2015-10-02 |
2015-11-18 |
Julius Maximillians Universitãt Würzburg |
GDF-15 as a diagnosis marker for melanoma
|
|
KR102621034B1
(ko)
|
2015-10-02 |
2024-01-03 |
율리우스-막시밀리안스 우니버지태트 뷔르츠부르크 |
면역 체크포인트 차단제를 이용한 치료의 임상적인 경과를 예측하기 위한 진단 마커로서의 gdf-15
|
|
HRP20250902T1
(hr)
|
2015-11-18 |
2025-09-26 |
Bristol-Myers Squibb Company |
Liječenje raka pluća korištenjem kombinacije anti‑pd‑1 antitijela i anti‑ctla‑4 antitijela
|
|
WO2017189724A1
(en)
*
|
2016-04-27 |
2017-11-02 |
Novartis Ag |
Antibodies against growth differentiation factor 15 and uses thereof
|
|
JP7155403B2
(ja)
*
|
2018-08-20 |
2022-10-18 |
ファイザー・インク |
抗ｇｄｆ１５抗体、組成物および使用の方法
|
|
EP4106815A4
(en)
|
2020-02-21 |
2024-04-24 |
The Children's Medical Center Corporation |
METHODS OF TREATING ASTHMA OR ALLERGIES
|
|
CN111393526B
(zh)
|
2020-03-30 |
2022-04-12 |
中国人民解放军第四军医大学 |
抗gdf15中和性单克隆抗体及其应用
|
|
KR20230107309A
(ko)
|
2020-11-10 |
2023-07-14 |
카탈임 게엠베하 |
항-gdf15 항체 및 암 치료용 투여 용법
|