JP2021523906A5 - - Google Patents
Info
- Publication number
- JP2021523906A5 JP2021523906A5 JP2020563980A JP2020563980A JP2021523906A5 JP 2021523906 A5 JP2021523906 A5 JP 2021523906A5 JP 2020563980 A JP2020563980 A JP 2020563980A JP 2020563980 A JP2020563980 A JP 2020563980A JP 2021523906 A5 JP2021523906 A5 JP 2021523906A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- seq
- pharmaceutical composition
- cancer
- Prior art date
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024130558A JP2024160301A (ja) | 2018-05-14 | 2024-08-07 | Lifに対する抗体及びそれらの投与形態 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18382327 | 2018-05-14 | ||
| EP18382327.7 | 2018-05-14 | ||
| EP18382359.0 | 2018-05-25 | ||
| EP18382359 | 2018-05-25 | ||
| EP19382208 | 2019-03-26 | ||
| EP19382208.7 | 2019-03-26 | ||
| EP19382331 | 2019-05-03 | ||
| EP19382331.7 | 2019-05-03 | ||
| PCT/IB2019/000541 WO2019220204A2 (en) | 2018-05-14 | 2019-05-13 | Antibodies against lif and dosage forms thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024130558A Division JP2024160301A (ja) | 2018-05-14 | 2024-08-07 | Lifに対する抗体及びそれらの投与形態 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021523906A JP2021523906A (ja) | 2021-09-09 |
| JP2021523906A5 true JP2021523906A5 (https=) | 2022-05-20 |
| JPWO2019220204A5 JPWO2019220204A5 (https=) | 2022-05-20 |
| JP7536654B2 JP7536654B2 (ja) | 2024-08-20 |
Family
ID=67902550
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020563980A Active JP7536654B2 (ja) | 2018-05-14 | 2019-05-13 | Lifに対する抗体及びそれらの投与形態 |
| JP2024130558A Pending JP2024160301A (ja) | 2018-05-14 | 2024-08-07 | Lifに対する抗体及びそれらの投与形態 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024130558A Pending JP2024160301A (ja) | 2018-05-14 | 2024-08-07 | Lifに対する抗体及びそれらの投与形態 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220064279A1 (https=) |
| EP (1) | EP3794031A2 (https=) |
| JP (2) | JP7536654B2 (https=) |
| KR (1) | KR20210008514A (https=) |
| CN (1) | CN112638941A (https=) |
| AU (1) | AU2019269131B2 (https=) |
| CA (1) | CA3099406A1 (https=) |
| MA (1) | MA52021A (https=) |
| SG (1) | SG11202011170YA (https=) |
| WO (1) | WO2019220204A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA52300A (fr) * | 2018-06-18 | 2021-04-21 | Fundacio Privada Inst Dinvestigacio Oncològica De Vall Hebron | Combinaison d'inhibiteurs de lif et d'agents anti-néoplasiques à base de platine à utiliser dans le traitement du cancer |
| KR102735988B1 (ko) | 2019-02-18 | 2024-12-03 | 일라이 릴리 앤드 캄파니 | 치료 항체 제제 |
| EP4069736A1 (en) * | 2019-12-04 | 2022-10-12 | MedImmune Limited | Antibodies against lif and uses thereof |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| WO1988007089A1 (en) | 1987-03-18 | 1988-09-22 | Medical Research Council | Altered antibodies |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| AU691811B2 (en) | 1993-06-16 | 1998-05-28 | Celltech Therapeutics Limited | Antibodies |
| HU230769B1 (hu) | 1999-01-15 | 2018-03-28 | Genentech Inc. | Módosított effektor-funkciójú polipeptid-változatok |
| US7361740B2 (en) | 2002-10-15 | 2008-04-22 | Pdl Biopharma, Inc. | Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis |
| ES2363358B1 (es) | 2009-04-03 | 2012-06-21 | FUNDACIÓ INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL D'HEBRON (Titular al | Agentes terapéuticos para el tratamiento de enfermedades asociadas con una proliferación celular indeseable. |
| EP2371860A1 (en) | 2010-04-05 | 2011-10-05 | Fundació Privada Institut d'Investigació Oncològica de Vall d'Hebron | Antibody recognising human leukemia inhibitory factor (LIF) and use of anti-LIF antibodies in the treatment of diseases associated with unwanted cell proliferation |
| CN106687134A (zh) | 2014-09-10 | 2017-05-17 | 加利福尼亚大学董事会 | 通过抗hLIF抗体靶向K‑RAS介导的信号转导通路和恶性肿瘤 |
| CA2963712A1 (en) | 2014-10-21 | 2016-04-28 | Ablynx Nv | Treatment of il-6r related diseases |
| EP3173483A1 (en) * | 2015-11-27 | 2017-05-31 | Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron | Agents for the treatment of diseases associated with undesired cell proliferation |
| US10583191B2 (en) * | 2016-12-19 | 2020-03-10 | Mosaic Biomedicals Slu | Antibodies against LIF and uses thereof |
| JP7423598B2 (ja) * | 2018-04-12 | 2024-01-29 | メドイミューン・リミテッド | がんの治療で使用するためのlif阻害剤とpd-1軸阻害剤との組み合わせ |
-
2019
- 2019-05-13 AU AU2019269131A patent/AU2019269131B2/en not_active Ceased
- 2019-05-13 JP JP2020563980A patent/JP7536654B2/ja active Active
- 2019-05-13 WO PCT/IB2019/000541 patent/WO2019220204A2/en not_active Ceased
- 2019-05-13 CN CN201980046565.4A patent/CN112638941A/zh active Pending
- 2019-05-13 EP EP19765782.8A patent/EP3794031A2/en active Pending
- 2019-05-13 SG SG11202011170YA patent/SG11202011170YA/en unknown
- 2019-05-13 CA CA3099406A patent/CA3099406A1/en active Pending
- 2019-05-13 US US17/055,279 patent/US20220064279A1/en not_active Abandoned
- 2019-05-13 MA MA052021A patent/MA52021A/fr unknown
- 2019-05-13 KR KR1020207035617A patent/KR20210008514A/ko not_active Ceased
-
2024
- 2024-08-07 JP JP2024130558A patent/JP2024160301A/ja active Pending
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