JP2020514310A5 - - Google Patents
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- JP2020514310A5 JP2020514310A5 JP2019539214A JP2019539214A JP2020514310A5 JP 2020514310 A5 JP2020514310 A5 JP 2020514310A5 JP 2019539214 A JP2019539214 A JP 2019539214A JP 2019539214 A JP2019539214 A JP 2019539214A JP 2020514310 A5 JP2020514310 A5 JP 2020514310A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- use according
- tgf
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023003484A JP7411832B2 (ja) | 2017-01-20 | 2023-01-13 | 抗ｔｇｆベータ抗体およびそれらの使用 |
| JP2023216508A JP7844425B2 (ja) | 2017-01-20 | 2023-12-22 | 抗ｔｇｆベータ抗体およびそれらの使用 |
| JP2025202422A JP2026036696A (ja) | 2017-01-20 | 2025-11-25 | 抗ｔｇｆベータ抗体およびそれらの使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762448800P | 2017-01-20 | 2017-01-20 | |
| EP17305061.8 | 2017-01-20 | ||
| US62/448,800 | 2017-01-20 | ||
| EP17305061 | 2017-01-20 | ||
| PCT/IB2018/000088 WO2018134681A1 (en) | 2017-01-20 | 2018-01-19 | Anti-tgf-beta antibodies and their use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023003484A Division JP7411832B2 (ja) | 2017-01-20 | 2023-01-13 | 抗ｔｇｆベータ抗体およびそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020514310A JP2020514310A (ja) | 2020-05-21 |
| JP2020514310A5 true JP2020514310A5 (https=) | 2021-02-18 |
| JP7213186B2 JP7213186B2 (ja) | 2023-01-26 |
Family
ID=61656071
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019539214A Active JP7213186B2 (ja) | 2017-01-20 | 2018-01-19 | 抗ｔｇｆベータ抗体およびそれらの使用 |
| JP2023003484A Active JP7411832B2 (ja) | 2017-01-20 | 2023-01-13 | 抗ｔｇｆベータ抗体およびそれらの使用 |
| JP2023216508A Active JP7844425B2 (ja) | 2017-01-20 | 2023-12-22 | 抗ｔｇｆベータ抗体およびそれらの使用 |
| JP2025202422A Pending JP2026036696A (ja) | 2017-01-20 | 2025-11-25 | 抗ｔｇｆベータ抗体およびそれらの使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023003484A Active JP7411832B2 (ja) | 2017-01-20 | 2023-01-13 | 抗ｔｇｆベータ抗体およびそれらの使用 |
| JP2023216508A Active JP7844425B2 (ja) | 2017-01-20 | 2023-12-22 | 抗ｔｇｆベータ抗体およびそれらの使用 |
| JP2025202422A Pending JP2026036696A (ja) | 2017-01-20 | 2025-11-25 | 抗ｔｇｆベータ抗体およびそれらの使用 |
Country Status (22)
| Country | Link |
|---|---|
| US (4) | US10766955B2 (https=) |
| JP (4) | JP7213186B2 (https=) |
| CN (2) | CN117417939A (https=) |
| AU (2) | AU2018209391B2 (https=) |
| BR (1) | BR112019014787A2 (https=) |
| CA (1) | CA3050845A1 (https=) |
| CL (1) | CL2019002011A1 (https=) |
| CO (1) | CO2019008946A2 (https=) |
| CR (1) | CR20190375A (https=) |
| DO (1) | DOP2019000191A (https=) |
| EC (1) | ECSP19059553A (https=) |
| IL (3) | IL268112B2 (https=) |
| MA (1) | MA47311A (https=) |
| MX (2) | MX2019008551A (https=) |
| MY (1) | MY200751A (https=) |
| NZ (1) | NZ796440A (https=) |
| PE (1) | PE20200734A1 (https=) |
| PH (1) | PH12019501635A1 (https=) |
| SG (1) | SG11201906660TA (https=) |
| TW (3) | TWI787230B (https=) |
| UY (1) | UY37575A (https=) |
| ZA (1) | ZA201904494B (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI787230B (zh) | 2017-01-20 | 2022-12-21 | 法商賽諾菲公司 | 抗ＴＧＦ-β抗體及其用途 |
| TWI832600B (zh) | 2017-01-20 | 2024-02-11 | 美商健臻公司 | 骨靶向抗體 |
| KR20210030411A (ko) * | 2018-07-10 | 2021-03-17 | 사노피 | Cd38 및 tgf-베타를 표적으로 하는 암에 대한 병용 요법 |
| EP3843788A1 (en) | 2018-08-30 | 2021-07-07 | HCW Biologics, Inc. | Single-chain chimeric polypeptides and uses thereof |
| CN112996805A (zh) | 2018-08-30 | 2021-06-18 | Hcw生物科技公司 | 多链嵌合多肽和其用途 |
| WO2020132647A1 (en) * | 2018-12-21 | 2020-06-25 | Northwestern University | Use of annexins in preventing and treating muscle membrane injury |
| EP3739588A1 (en) * | 2019-05-13 | 2020-11-18 | Koninklijke Philips N.V. | Assessment of multiple signaling pathway activity score in airway epithelial cells to predict airway epithelial abnormality and airway cancer risk |
| JP7713393B2 (ja) | 2019-06-21 | 2025-07-25 | イミュニティーバイオ インコーポレイテッド | 多鎖キメラポリペプチドおよびその使用 |
| EP4103599A1 (en) | 2020-02-11 | 2022-12-21 | HCW Biologics, Inc. | Methods of activating regulatory t cells |
| KR20220140535A (ko) | 2020-02-11 | 2022-10-18 | 에이치씨더블유 바이올로직스, 인크. | 크로마토그래피 수지 및 이의 용도 |
| US12115191B2 (en) | 2020-02-11 | 2024-10-15 | Immunitybio, Inc. | Methods of treating age-related and inflammatory diseases |
| EP4143231A1 (en) | 2020-04-29 | 2023-03-08 | HCW Biologics, Inc. | Anti-cd26 proteins and uses thereof |
| CN113563473A (zh) | 2020-04-29 | 2021-10-29 | 三生国健药业（上海）股份有限公司 | 四价双特异性抗体、其制备方法和用途 |
| US12024545B2 (en) | 2020-06-01 | 2024-07-02 | HCW Biologics, Inc. | Methods of treating aging-related disorders |
| US20220119513A1 (en) * | 2020-06-08 | 2022-04-21 | Zoetis Services Llc | Anti-tgfb antibodies and therapeutic uses thereof |
| CN112940119B (zh) * | 2021-04-26 | 2022-05-20 | 北京芳渟阳生生物科技有限公司 | 一种单克隆抗体及其与间充质干细胞外泌体的联合应用 |
| KR20240022608A (ko) * | 2021-06-18 | 2024-02-20 | 젠자임 코포레이션 | 항-tgf-베타 항체 제형 및 이의 용도 |
| IL310164A (en) | 2021-08-11 | 2024-03-01 | Hcw Biologics Inc | Multi-chain chimeric polypeptides and use thereof in the treatment of liver diseases |
| CN115707716A (zh) * | 2021-08-18 | 2023-02-21 | 丹生医药技术(上海)有限公司 | 一种TGF-β/VEGF双功能抗体融合蛋白 |
| MX2024005344A (es) * | 2021-11-01 | 2024-07-19 | Genzyme Corp | Tratamiento de la osteogenesis imperfecta. |
| EP4507711A1 (en) | 2022-04-13 | 2025-02-19 | ImmunityBio, Inc. | Multi-chain chimeric polypeptide for use in the treatment of treating neuroinflammatory disorder |
| CA3255428A1 (en) | 2022-04-13 | 2023-10-19 | Immunitybio, Inc. | Methods of modulating circadian clock gene expression |
| CN115508565B (zh) * | 2022-10-20 | 2024-11-15 | 成都医学院第一附属医院 | Cilp1作为肾纤维化生物标志物的应用 |
Family Cites Families (55)
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| US4867973A (en) | 1984-08-31 | 1989-09-19 | Cytogen Corporation | Antibody-therapeutic agent conjugates |
| US4671958A (en) | 1982-03-09 | 1987-06-09 | Cytogen Corporation | Antibody conjugates for the delivery of compounds to target sites |
| US5571714A (en) | 1988-12-22 | 1996-11-05 | Celtrix Pharmaceuticals, Inc. | Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use |
| ES2156149T3 (es) | 1992-12-04 | 2001-06-16 | Medical Res Council | Proteinas de union multivalente y multiespecificas, su fabricacion y su uso. |
| US5824655A (en) | 1995-02-15 | 1998-10-20 | The University Of Utah | Anti-transforming growth factor-β gene therapy |
| GB9601081D0 (en) | 1995-10-06 | 1996-03-20 | Cambridge Antibody Tech | Specific binding members for human transforming growth factor beta;materials and methods |
| MX336813B (es) | 1996-02-09 | 2016-02-02 | Abbvie Biotechnology Ltd | Anticuerpos humanos que ligan el tnfa humano. |
| US6455495B1 (en) | 1997-02-14 | 2002-09-24 | The Salk Institute For Biological Studies | Methods and compositions for delivery of therapeutic agents to bone tissue employing conjugates of negatively charged peptide oligomers with therapeutic agents |
| MY131805A (en) | 1997-09-18 | 2007-09-28 | Biogen Idec Inc | Synergistic composition and methods for treating neoplastic or cancerous growths and for restoring or boosting hematopoiesis. |
| EP1074563A1 (en) | 1999-08-02 | 2001-02-07 | F. Hoffmann-La Roche Ag | Chimeric polypeptides enhancing dimer formation through electrostatic interactions and disulfide bond, method for production and uses thereof |
| US20020063763A1 (en) | 2000-11-29 | 2002-05-30 | Mantell David Allen | Apparatus and method for removing air bubbles from an ink jet printhead |
| US20030224501A1 (en) | 2000-03-17 | 2003-12-04 | Young Paul E. | Bone morphogenic protein polynucleotides, polypeptides, and antibodies |
| JP2006523609A (ja) | 2002-12-31 | 2006-10-19 | アルタス ファーマシューティカルズ インコーポレイテッド | タンパク質結晶およびイオン性ポリマーの複合体 |
| JP2006525362A (ja) | 2003-04-30 | 2006-11-09 | ジェンザイム コーポレーション | 腎機能不全を治療するためのＴＧＦ−βアンタゴニストとレニン−アンジオテンシン−アルドステロン系アンタゴニストとの併用 |
| WO2005010049A2 (en) | 2003-07-09 | 2005-02-03 | Eli Lilly And Company | Tgf-beta1 ligands |
| EP1740615B1 (en) * | 2004-03-31 | 2014-11-05 | Genentech, Inc. | Humanized anti-tgf-beta antibodies |
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| US8574577B2 (en) | 2008-01-03 | 2013-11-05 | The Scripps Research Institute | VEGF antibodies comprising modular recognition domains |
| KR101658247B1 (ko) | 2008-01-03 | 2016-09-22 | 더 스크립스 리서치 인스티튜트 | 모듈 인식 도메인을 통한 항체 표적화 |
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| CA3253628A1 (en) | 2010-03-05 | 2025-11-29 | The Johns Hopkins University | Compositions and methods for targeted immunomodulatory antibodies and fusion proteins |
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| US11786457B2 (en) | 2015-01-30 | 2023-10-17 | President And Fellows Of Harvard College | Peritumoral and intratumoral materials for cancer therapy |
| TWI733661B (zh) | 2015-03-04 | 2021-07-21 | 美商健臻公司 | 以高親合性、結合性及特異性結合轉化生長因子－β１的經修飾ＩｇＧ抗體 |
| EP3770171A1 (en) | 2015-04-03 | 2021-01-27 | XOMA Technology Ltd. | Treatment of cancer using inhibitors of tgf-beta and pd-1 |
| KR20250004095A (ko) | 2015-04-17 | 2025-01-07 | 브리스톨-마이어스 스큅 컴퍼니 | 항-pd-1 항체 및 또 다른 항체의 조합물을 포함하는 조성물 |
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| US20200231652A1 (en) | 2015-08-31 | 2020-07-23 | National Research Council Of Canada | Tgf-b-receptor ectodomain fusion molecules and uses thereof |
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| TWI832600B (zh) | 2017-01-20 | 2024-02-11 | 美商健臻公司 | 骨靶向抗體 |
| TWI787230B (zh) | 2017-01-20 | 2022-12-21 | 法商賽諾菲公司 | 抗ＴＧＦ-β抗體及其用途 |
-
2018
- 2018-01-18 TW TW107101789A patent/TWI787230B/zh active
- 2018-01-18 TW TW111145565A patent/TWI856437B/zh active
- 2018-01-18 TW TW113140547A patent/TW202506185A/zh unknown
- 2018-01-19 IL IL268112A patent/IL268112B2/en unknown
- 2018-01-19 BR BR112019014787-0A patent/BR112019014787A2/pt unknown
- 2018-01-19 MX MX2019008551A patent/MX2019008551A/es unknown
- 2018-01-19 SG SG11201906660TA patent/SG11201906660TA/en unknown
- 2018-01-19 CA CA3050845A patent/CA3050845A1/en active Pending
- 2018-01-19 MY MYPI2019003989A patent/MY200751A/en unknown
- 2018-01-19 CR CR20190375A patent/CR20190375A/es unknown
- 2018-01-19 JP JP2019539214A patent/JP7213186B2/ja active Active
- 2018-01-19 UY UY0001037575A patent/UY37575A/es not_active Application Discontinuation
- 2018-01-19 IL IL311866A patent/IL311866B2/en unknown
- 2018-01-19 PE PE2019001465A patent/PE20200734A1/es unknown
- 2018-01-19 CN CN202311230922.7A patent/CN117417939A/zh active Pending
- 2018-01-19 CN CN201880007975.3A patent/CN110520441B8/zh active Active
- 2018-01-19 NZ NZ796440A patent/NZ796440A/en unknown
- 2018-01-19 AU AU2018209391A patent/AU2018209391B2/en active Active
- 2018-01-19 MA MA047311A patent/MA47311A/fr unknown
- 2018-01-19 US US15/875,532 patent/US10766955B2/en active Active
-
2019
- 2019-07-09 ZA ZA2019/04494A patent/ZA201904494B/en unknown
- 2019-07-12 PH PH12019501635A patent/PH12019501635A1/en unknown
- 2019-07-17 MX MX2023002588A patent/MX2023002588A/es unknown
- 2019-07-18 CL CL2019002011A patent/CL2019002011A1/es unknown
- 2019-07-19 DO DO2019000191A patent/DOP2019000191A/es unknown
- 2019-08-16 CO CONC2019/0008946A patent/CO2019008946A2/es unknown
- 2019-08-19 EC ECSENADI201959553A patent/ECSP19059553A/es unknown
-
2020
- 2020-07-16 US US16/931,198 patent/US11242384B2/en active Active
-
2021
- 2021-12-23 US US17/561,510 patent/US12049496B2/en active Active
-
2023
- 2023-01-13 JP JP2023003484A patent/JP7411832B2/ja active Active
- 2023-12-22 JP JP2023216508A patent/JP7844425B2/ja active Active
-
2024
- 2024-07-09 US US18/767,270 patent/US20250026821A1/en active Pending
- 2024-11-13 AU AU2024264593A patent/AU2024264593A1/en active Pending
-
2025
- 2025-10-05 IL IL323799A patent/IL323799A/en unknown
- 2025-11-25 JP JP2025202422A patent/JP2026036696A/ja active Pending
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