JPWO2022009121A5 - - Google Patents
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- Publication number
- JPWO2022009121A5 JPWO2022009121A5 JP2023501632A JP2023501632A JPWO2022009121A5 JP WO2022009121 A5 JPWO2022009121 A5 JP WO2022009121A5 JP 2023501632 A JP2023501632 A JP 2023501632A JP 2023501632 A JP2023501632 A JP 2023501632A JP WO2022009121 A5 JPWO2022009121 A5 JP WO2022009121A5
- Authority
- JP
- Japan
- Prior art keywords
- influenza
- cov
- sars
- fragment
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000012634 fragment Substances 0.000 claims 37
- 206010022000 influenza Diseases 0.000 claims 28
- 230000002163 immunogen Effects 0.000 claims 26
- 208000025721 COVID-19 Diseases 0.000 claims 13
- 241001678559 COVID-19 virus Species 0.000 claims 12
- 229940001442 combination vaccine Drugs 0.000 claims 11
- 108020001507 fusion proteins Proteins 0.000 claims 11
- 102000037865 fusion proteins Human genes 0.000 claims 11
- 229940096437 Protein S Drugs 0.000 claims 10
- 101000629318 Severe acute respiratory syndrome coronavirus 2 Spike glycoprotein Proteins 0.000 claims 10
- 101710198474 Spike protein Proteins 0.000 claims 10
- 239000000427 antigen Substances 0.000 claims 10
- 102000036639 antigens Human genes 0.000 claims 10
- 108091007433 antigens Proteins 0.000 claims 10
- 230000000890 antigenic effect Effects 0.000 claims 9
- 230000009260 cross reactivity Effects 0.000 claims 9
- 101710154606 Hemagglutinin Proteins 0.000 claims 8
- 102000005348 Neuraminidase Human genes 0.000 claims 8
- 108010006232 Neuraminidase Proteins 0.000 claims 8
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 8
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 8
- 101710176177 Protein A56 Proteins 0.000 claims 8
- 239000000185 hemagglutinin Substances 0.000 claims 8
- 239000013598 vector Substances 0.000 claims 7
- 210000002845 virion Anatomy 0.000 claims 5
- 108010041986 DNA Vaccines Proteins 0.000 claims 4
- 229940021995 DNA vaccine Drugs 0.000 claims 4
- 229940022005 RNA vaccine Drugs 0.000 claims 4
- 108700021021 mRNA Vaccine Proteins 0.000 claims 4
- 108091033319 polynucleotide Proteins 0.000 claims 4
- 102000040430 polynucleotide Human genes 0.000 claims 4
- 239000002157 polynucleotide Substances 0.000 claims 4
- 239000002671 adjuvant Substances 0.000 claims 3
- 229960003971 influenza vaccine Drugs 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 230000001932 seasonal effect Effects 0.000 claims 3
- 239000013603 viral vector Substances 0.000 claims 3
- 229940022962 COVID-19 vaccine Drugs 0.000 claims 2
- 101000641175 Human papillomavirus type 18 Major capsid protein L1 Proteins 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 208000002672 hepatitis B Diseases 0.000 claims 2
- 201000010284 hepatitis E Diseases 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 229960001226 live attenuated influenza Drugs 0.000 claims 2
- 229940035032 monophosphoryl lipid a Drugs 0.000 claims 2
- 150000007523 nucleic acids Chemical group 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 claims 1
- 108020004414 DNA Proteins 0.000 claims 1
- 241000991587 Enterovirus C Species 0.000 claims 1
- 101100209954 Human papillomavirus type 16 L1 gene Proteins 0.000 claims 1
- 241000712079 Measles morbillivirus Species 0.000 claims 1
- 241000711386 Mumps virus Species 0.000 claims 1
- 241000710799 Rubella virus Species 0.000 claims 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 241000710772 Yellow fever virus Species 0.000 claims 1
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000007764 o/w emulsion Substances 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 229940124740 quadrivalent influenza vaccine Drugs 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 229940031439 squalene Drugs 0.000 claims 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 claims 1
- 229960000172 trivalent influenza vaccine Drugs 0.000 claims 1
- 229940051021 yellow-fever virus Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2010425.3 | 2020-07-07 | ||
| GB2010425.3A GB2596820A (en) | 2020-07-07 | 2020-07-07 | Combination vaccine |
| PCT/IB2021/056102 WO2022009121A1 (en) | 2020-07-07 | 2021-07-07 | Sars-cov-2 and influenza combination vaccine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023533772A JP2023533772A (ja) | 2023-08-04 |
| JPWO2022009121A5 true JPWO2022009121A5 (enExample) | 2024-07-16 |
Family
ID=72050416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023501632A Pending JP2023533772A (ja) | 2020-07-07 | 2021-07-07 | SARS-CoV-2及びインフルエンザ混合ワクチン |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20230256085A1 (enExample) |
| EP (1) | EP4178612A1 (enExample) |
| JP (1) | JP2023533772A (enExample) |
| KR (1) | KR20230049084A (enExample) |
| CN (1) | CN117957016A (enExample) |
| AR (1) | AR122899A1 (enExample) |
| AU (1) | AU2021303789A1 (enExample) |
| BR (1) | BR112023000323A2 (enExample) |
| CA (1) | CA3184878A1 (enExample) |
| CO (1) | CO2023001072A2 (enExample) |
| GB (1) | GB2596820A (enExample) |
| IL (1) | IL299735A (enExample) |
| MX (1) | MX2023000411A (enExample) |
| TW (1) | TW202207979A (enExample) |
| WO (1) | WO2022009121A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10925958B2 (en) | 2016-11-11 | 2021-02-23 | Modernatx, Inc. | Influenza vaccine |
| WO2018170245A1 (en) | 2017-03-15 | 2018-09-20 | Modernatx, Inc. | Broad spectrum influenza virus vaccine |
| US11547673B1 (en) | 2020-04-22 | 2023-01-10 | BioNTech SE | Coronavirus vaccine |
| WO2022083768A1 (zh) * | 2020-10-23 | 2022-04-28 | 江苏省疾病预防控制中心(江苏省公共卫生研究院) | 免疫原性组合物及其应用 |
| CN113293145B (zh) * | 2021-02-01 | 2022-08-26 | 上海青赛生物科技有限公司 | 一种麻疹病毒活载体新冠疫苗 |
| WO2022221440A1 (en) * | 2021-04-14 | 2022-10-20 | Modernatx, Inc. | Influenza-coronavirus combination vaccines |
| CN113462700B (zh) * | 2021-05-07 | 2023-06-09 | 杨光华 | SARS-CoV-2线性DNA疫苗 |
| CN114717251B (zh) * | 2021-08-24 | 2023-03-24 | 广州恩宝生物医药科技有限公司 | 一种用于预防SARS-CoV-2原始株和Beta株的腺病毒载体疫苗 |
| WO2023047419A1 (en) * | 2021-09-24 | 2023-03-30 | Bharat Biotech International Limited | A vaccine for coronavirus and influenza virus, and method for preparation thereof |
| CN113755644B (zh) * | 2021-09-24 | 2024-05-03 | 中国科学院武汉病毒研究所 | 一种检测新型冠状病毒Alpha和Delta突变体试剂盒及应用 |
| US12186387B2 (en) | 2021-11-29 | 2025-01-07 | BioNTech SE | Coronavirus vaccine |
| CN114891817A (zh) * | 2022-04-15 | 2022-08-12 | 华南理工大学 | 一种多聚肽及其制备方法与应用 |
| US11878055B1 (en) | 2022-06-26 | 2024-01-23 | BioNTech SE | Coronavirus vaccine |
| WO2024174012A1 (pt) * | 2023-02-24 | 2024-08-29 | Instituto Butantan | Composição imunogênica, uso da mesma e processo de obtenção de uma composição imunogênica combinada contra covid-19 e influenza sazonal |
| CN115992101B (zh) * | 2023-03-22 | 2023-07-28 | 深圳市卫光生物制品股份有限公司 | 一种流感病毒裂解疫苗原液的制备方法 |
| CN116327910B (zh) * | 2023-03-31 | 2024-05-03 | 北京吉诺卫生物科技有限公司 | 一种新冠病毒、流感病毒和/或rsv的联合疫苗、其制备方法与应用 |
| CN116350769B (zh) * | 2023-03-31 | 2024-07-19 | 北京吉诺卫生物科技有限公司 | 一种新冠病毒和流感病毒的联合疫苗、其制备方法与应用 |
| EP4710936A1 (en) * | 2023-05-10 | 2026-03-18 | National University Corporation Hokkaido University | Combination vaccine for prevention of influenza and coronavirus infections |
| CN118141906B (zh) * | 2024-02-22 | 2025-08-22 | 安徽智飞龙科马生物制药有限公司 | 一种新冠流感联合疫苗及其制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4737462A (en) | 1982-10-19 | 1988-04-12 | Cetus Corporation | Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β |
| US4518584A (en) | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
| GB9419979D0 (en) * | 1994-10-04 | 1994-11-16 | Medeva Holdings Bv | Vaccine compositions |
| CN1775287A (zh) * | 2004-11-16 | 2006-05-24 | 北京科兴生物制品有限公司 | 一种sars流感二价联合疫苗及其制备工艺 |
| GB0822001D0 (en) * | 2008-12-02 | 2009-01-07 | Glaxosmithkline Biolog Sa | Vaccine |
| BR112013019850B1 (pt) * | 2011-02-04 | 2023-02-28 | Zoetis Services Llc | Composições de vacina e seu uso no tratamento ou prevenção de doenças respiratórias infecciosas caninas |
| GB201108879D0 (en) | 2011-05-25 | 2011-07-06 | Isis Innovation | Vector |
| US20130236494A1 (en) * | 2012-03-06 | 2013-09-12 | Crucell Holland B.V. | Vaccination against influenza |
| CN107961371B (zh) * | 2017-04-19 | 2020-08-11 | 武汉博沃生物科技有限公司 | 季节流感-rsv联合疫苗及其制备方法和应用 |
| CN110974950B (zh) * | 2020-03-05 | 2020-08-07 | 广州恩宝生物医药科技有限公司 | 一种用于预防SARS-CoV-2感染的腺病毒载体疫苗 |
| CN111217917B (zh) * | 2020-02-26 | 2020-10-23 | 康希诺生物股份公司 | 一种新型冠状病毒SARS-CoV-2疫苗及其制备方法 |
| CN111218458B (zh) * | 2020-02-27 | 2020-11-20 | 珠海丽凡达生物技术有限公司 | 编码SARS-CoV-2病毒抗原的mRNA和疫苗及疫苗的制备方法 |
-
2020
- 2020-07-07 GB GB2010425.3A patent/GB2596820A/en not_active Withdrawn
-
2021
- 2021-07-07 KR KR1020237003756A patent/KR20230049084A/ko active Pending
- 2021-07-07 AU AU2021303789A patent/AU2021303789A1/en active Pending
- 2021-07-07 CN CN202180054553.3A patent/CN117957016A/zh active Pending
- 2021-07-07 TW TW110125037A patent/TW202207979A/zh unknown
- 2021-07-07 EP EP21740222.1A patent/EP4178612A1/en active Pending
- 2021-07-07 CA CA3184878A patent/CA3184878A1/en active Pending
- 2021-07-07 IL IL299735A patent/IL299735A/en unknown
- 2021-07-07 AR ARP210101904A patent/AR122899A1/es unknown
- 2021-07-07 WO PCT/IB2021/056102 patent/WO2022009121A1/en not_active Ceased
- 2021-07-07 MX MX2023000411A patent/MX2023000411A/es unknown
- 2021-07-07 JP JP2023501632A patent/JP2023533772A/ja active Pending
- 2021-07-07 BR BR112023000323A patent/BR112023000323A2/pt unknown
- 2021-07-07 US US18/015,025 patent/US20230256085A1/en active Pending
-
2023
- 2023-01-31 CO CONC2023/0001072A patent/CO2023001072A2/es unknown
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