JPWO2021167095A5 - - Google Patents
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- Publication number
- JPWO2021167095A5 JPWO2021167095A5 JP2022501092A JP2022501092A JPWO2021167095A5 JP WO2021167095 A5 JPWO2021167095 A5 JP WO2021167095A5 JP 2022501092 A JP2022501092 A JP 2022501092A JP 2022501092 A JP2022501092 A JP 2022501092A JP WO2021167095 A5 JPWO2021167095 A5 JP WO2021167095A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- amide solvent
- methylpyrrolidone
- phenylethylamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025232373A JP2026041900A (ja) | 2020-02-21 | 2025-12-04 | 光学分割されたトロロックス中間体およびその製造方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020028614 | 2020-02-21 | ||
| JP2020028614 | 2020-02-21 | ||
| PCT/JP2021/006465 WO2021167095A1 (ja) | 2020-02-21 | 2021-02-19 | 光学分割されたトロロックス中間体およびその製造方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025232373A Division JP2026041900A (ja) | 2020-02-21 | 2025-12-04 | 光学分割されたトロロックス中間体およびその製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2021167095A1 JPWO2021167095A1 (https=) | 2021-08-26 |
| JPWO2021167095A5 true JPWO2021167095A5 (https=) | 2024-02-29 |
| JP7840259B2 JP7840259B2 (ja) | 2026-04-03 |
Family
ID=77390820
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022501092A Active JP7840259B2 (ja) | 2020-02-21 | 2021-02-19 | 光学分割されたトロロックス中間体およびその製造方法 |
| JP2025232373A Pending JP2026041900A (ja) | 2020-02-21 | 2025-12-04 | 光学分割されたトロロックス中間体およびその製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025232373A Pending JP2026041900A (ja) | 2020-02-21 | 2025-12-04 | 光学分割されたトロロックス中間体およびその製造方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12509434B2 (https=) |
| EP (1) | EP4108658A4 (https=) |
| JP (2) | JP7840259B2 (https=) |
| KR (1) | KR20220143897A (https=) |
| CN (1) | CN115066420B (https=) |
| BR (1) | BR112022016508A2 (https=) |
| IL (1) | IL295785A (https=) |
| WO (1) | WO2021167095A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CR20250133A (es) | 2022-09-12 | 2025-06-26 | Ptc Therapeutics Inc | Granulos para suspension |
| AU2023352262A1 (en) | 2022-09-30 | 2025-04-24 | Ptc Therapeutics, Inc. | Oxidative cleavage method of trolox amide |
| WO2025117870A1 (en) | 2023-12-01 | 2025-06-05 | Ptc Therapeutics, Inc. | Method of electrolytic oxidative cleavage of trolox amide |
| WO2025193975A1 (en) | 2024-03-13 | 2025-09-18 | Ptc Therapeutics, Inc. | Formulations for stabilizing dissolution of medicaments |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA739471B (en) * | 1972-12-22 | 1974-08-28 | Hoffmann La Roche | Chromane derivatives |
| US3947473A (en) | 1972-12-22 | 1976-03-30 | Hoffman-La Roche Inc. | Antioxidant chroman compounds |
| US4003919A (en) | 1973-11-19 | 1977-01-18 | Hoffmann-La Roche Inc. | Antioxidant chroman compounds |
| US4026907A (en) | 1973-11-19 | 1977-05-31 | Hoffmann-La Roche Inc. | Antioxidant chroman compounds |
| WO2002012221A1 (en) * | 2000-08-03 | 2002-02-14 | Kuraray Co., Ltd. | Method for optical resolution of (±)-6-hydroxy-2,5,7,8-tetramethylcoumarone-2-carboxylic acid |
| JP2002167381A (ja) * | 2000-08-03 | 2002-06-11 | Kuraray Co Ltd | （±）−６−ヒドロキシ−２，５，７，８−テトラメチルクロマン−２−カルボン酸の光学分割法 |
| EA038941B1 (ru) | 2007-11-06 | 2021-11-12 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | ПРОИЗВОДНЫЕ 4-(п-ХИНОНИЛ)-2-ГИДРОКСИБУТАНАМИДА ДЛЯ ЛЕЧЕНИЯ МИТОХОНДРИАЛЬНЫХ ЗАБОЛЕВАНИЙ |
| JP5598330B2 (ja) * | 2008-10-29 | 2014-10-01 | 三菱瓦斯化学株式会社 | 光学活性有機カルボン酸の製造方法 |
| KR20110086723A (ko) | 2008-11-07 | 2011-07-29 | 시플라 리미티드 | 조피클론을 광학분할하는 방법 |
| JP5641802B2 (ja) * | 2010-07-26 | 2014-12-17 | 株式会社トクヤマ | （ｓ）−４−〔（４−クロロフェニル）（２−ピリジル）メトキシ〕ピペリジンのジアステレオマー塩の製造方法 |
| JPWO2013011999A1 (ja) * | 2011-07-20 | 2015-02-23 | 株式会社カネカ | 光学活性２−メチルプロリン誘導体の製造法 |
| CN105164105B (zh) | 2013-04-10 | 2018-01-30 | 第一三共株式会社 | 吡咯衍生物的结晶及其制备方法 |
| DK3233786T3 (da) * | 2014-12-16 | 2022-05-09 | Ptc Therapeutics Inc | Polymorfe og amorfe former af (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6- dioxocyclohexa-1,4-dienyl)butanamid |
| EP3233819A1 (en) * | 2014-12-16 | 2017-10-25 | Bioelectron Technology Corporation | Methods for chiral resolution of trolox |
| JP2020028614A (ja) | 2018-08-24 | 2020-02-27 | 株式会社三共 | 遊技機 |
-
2021
- 2021-02-19 EP EP21757166.0A patent/EP4108658A4/en active Pending
- 2021-02-19 IL IL295785A patent/IL295785A/en unknown
- 2021-02-19 WO PCT/JP2021/006465 patent/WO2021167095A1/ja not_active Ceased
- 2021-02-19 JP JP2022501092A patent/JP7840259B2/ja active Active
- 2021-02-19 US US17/801,237 patent/US12509434B2/en active Active
- 2021-02-19 CN CN202180015723.7A patent/CN115066420B/zh active Active
- 2021-02-19 BR BR112022016508A patent/BR112022016508A2/pt unknown
- 2021-02-19 KR KR1020227032224A patent/KR20220143897A/ko active Pending
-
2025
- 2025-12-04 JP JP2025232373A patent/JP2026041900A/ja active Pending
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