JPWO2021119539A5 - - Google Patents
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- JPWO2021119539A5 JPWO2021119539A5 JP2022535807A JP2022535807A JPWO2021119539A5 JP WO2021119539 A5 JPWO2021119539 A5 JP WO2021119539A5 JP 2022535807 A JP2022535807 A JP 2022535807A JP 2022535807 A JP2022535807 A JP 2022535807A JP WO2021119539 A5 JPWO2021119539 A5 JP WO2021119539A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally
- domain
- expression cassette
- cells
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962947427P | 2019-12-12 | 2019-12-12 | |
| US62/947,427 | 2019-12-12 | ||
| US202063116103P | 2020-11-19 | 2020-11-19 | |
| US63/116,103 | 2020-11-19 | ||
| PCT/US2020/064688 WO2021119539A1 (en) | 2019-12-12 | 2020-12-11 | Method and compositions for regulated armoring of cells |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2023506015A JP2023506015A (ja) | 2023-02-14 |
| JPWO2021119539A5 true JPWO2021119539A5 (https=) | 2023-12-19 |
| JP2023506015A5 JP2023506015A5 (https=) | 2023-12-19 |
| JP7792335B2 JP7792335B2 (ja) | 2025-12-25 |
Family
ID=76329099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022535807A Active JP7792335B2 (ja) | 2019-12-12 | 2020-12-11 | 細胞の調節されたアーマリングのための方法及び組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230011052A1 (https=) |
| EP (1) | EP4072596A4 (https=) |
| JP (1) | JP7792335B2 (https=) |
| KR (1) | KR20220115602A (https=) |
| CN (1) | CN115087466A (https=) |
| AU (1) | AU2020399805A1 (https=) |
| CA (1) | CA3160614A1 (https=) |
| IL (1) | IL293570A (https=) |
| TW (1) | TW202136507A (https=) |
| WO (1) | WO2021119539A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12180296B2 (en) * | 2019-01-08 | 2024-12-31 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Cross species single domain antibodies targeting mesothelin for treating solid tumors |
| KR20240022575A (ko) * | 2021-06-16 | 2024-02-20 | 센티 바이오사이언시스, 인코포레이티드 | 아머링된 키메라 수용체 및 이의 사용 방법 |
| EP4370697A4 (en) * | 2021-07-12 | 2026-02-25 | Childrens Hospital Med Ct | DIFFERENTIAL EXPRESSION OF CXCR4 ON HEMATOPOIETIC PROGENITOR CELLS COMPARED TO DIRECT ECOTROPISM AND LONG-TERM STEM CELL ENGRAVING |
| US20240327521A1 (en) * | 2021-07-29 | 2024-10-03 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Synthetic nucleic acid elements for enhancing car t cell efficacy |
| CA3232972A1 (en) * | 2021-10-28 | 2023-05-04 | Steven C. Quay | Endoxifen for treatment of cancers |
| CN118556086A (zh) * | 2021-11-09 | 2024-08-27 | 美国政府(由卫生和人类服务部的部长所代表) | 靶向磷脂酰肌醇蛋白聚糖-3（gpc3）的含有igg4铰链的嵌合抗原受体及其用途 |
| WO2023114910A2 (en) * | 2021-12-15 | 2023-06-22 | Senti Biosciences, Inc. | Activation responsive promoters and uses thereof |
| WO2023215724A1 (en) * | 2022-05-01 | 2023-11-09 | Factor Bioscience Inc. | Methods for reprogramming and gene editing cells |
| WO2024102943A1 (en) * | 2022-11-09 | 2024-05-16 | Senti Biosciences, Inc. | Armed chimeric receptors and methods of use thereof |
| TW202434618A (zh) * | 2023-01-09 | 2024-09-01 | 美商奧特佩斯生化股份有限公司 | 經設計之細胞激素組合物及使用方法 |
| AU2024309243A1 (en) | 2023-06-27 | 2026-01-29 | Lyell Immunopharma, Inc. | Il-12 stability variants |
| WO2025049866A1 (en) * | 2023-08-30 | 2025-03-06 | Senti Biosciences, Inc. | Engineered minimal core promoter and uses thereof |
| WO2025072098A1 (en) * | 2023-09-28 | 2025-04-03 | Dna Twopointo Inc. | Inducible expression systems |
| WO2025144762A1 (en) * | 2023-12-28 | 2025-07-03 | Immorta Bio, Inc. | Reprogrammed cell modulation of cancer microenvironment by tumor homing personalized regenerative cells |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2479254A1 (en) * | 2005-08-24 | 2012-07-25 | The Scripps Research Institute | Translation enhancer-element dependent vector systems |
| CA2794196A1 (en) * | 2010-03-23 | 2011-09-29 | Intrexon Corporation | Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof |
| US20130158098A1 (en) | 2010-06-21 | 2013-06-20 | The Board Of Trustees Of The Leland Standford Junior University | Alkenyl Substituted Cycloaliphatic Compounds as Chemical Inducers of Proximity |
| SG11201407972RA (en) * | 2012-06-01 | 2015-01-29 | Us Health | High-affinity monoclonal antibodies to glypican-3 and use thereof |
| CN103772506A (zh) | 2012-10-22 | 2014-05-07 | 北京唯尚立德生物科技有限公司 | 一种“转录激活子样效应因子-功能基团-雌激素受体”功能蛋白及其应用 |
| MX2017012939A (es) * | 2015-04-08 | 2018-05-22 | Novartis Ag | Terapias cd20, terapias cd22 y terapias de combinacion con una celula que expresa un receptor quimerico de antigeno (car) de cd19. |
| US10550379B2 (en) | 2015-06-29 | 2020-02-04 | The Board Of Trustees Of The Leland Stanford Junior University | Degron fusion constructs and methods for controlling protein production |
| US10266844B2 (en) * | 2015-07-31 | 2019-04-23 | California Institute Of Technology | Activity-dependent expression of nucleic acids |
| JP7500195B2 (ja) * | 2016-08-23 | 2024-06-17 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | タンパク質分解により切断可能なキメラポリペプチド及びそれらの使用方法 |
| CN110291200B (zh) | 2016-12-12 | 2024-05-14 | 西雅图儿童医院（Dba西雅图儿童研究所） | 对哺乳动物细胞中转基因表达的药剂配体诱导具有增大的灵敏度的嵌合转录因子变异体 |
| KR20190102259A (ko) * | 2017-01-10 | 2019-09-03 | 인트렉손 코포레이션 | 신규의 유전자 스위치 발현 시스템을 통한 폴리펩티드의 발현 조절 |
| CN111683962B (zh) * | 2017-11-10 | 2025-05-16 | 美国政府(由卫生和人类服务部的部长所代表) | 靶向肿瘤抗原的嵌合抗原受体 |
| IL275462B2 (en) * | 2017-12-22 | 2026-01-01 | Genentech Inc | Targeted integration of nucleic acids |
| CA3138576A1 (en) | 2019-05-16 | 2020-11-19 | Trustees Of Boston University | Regulated synthetic gene expression systems |
-
2020
- 2020-12-11 WO PCT/US2020/064688 patent/WO2021119539A1/en not_active Ceased
- 2020-12-11 KR KR1020227023864A patent/KR20220115602A/ko active Pending
- 2020-12-11 JP JP2022535807A patent/JP7792335B2/ja active Active
- 2020-12-11 IL IL293570A patent/IL293570A/en unknown
- 2020-12-11 CA CA3160614A patent/CA3160614A1/en active Pending
- 2020-12-11 AU AU2020399805A patent/AU2020399805A1/en active Pending
- 2020-12-11 EP EP20898212.4A patent/EP4072596A4/en active Pending
- 2020-12-11 CN CN202080096411.9A patent/CN115087466A/zh active Pending
- 2020-12-14 TW TW109144125A patent/TW202136507A/zh unknown
-
2022
- 2022-06-10 US US17/838,118 patent/US20230011052A1/en active Pending
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