JPWO2022266396A5 - - Google Patents

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Publication number
JPWO2022266396A5
JPWO2022266396A5 JP2023577531A JP2023577531A JPWO2022266396A5 JP WO2022266396 A5 JPWO2022266396 A5 JP WO2022266396A5 JP 2023577531 A JP2023577531 A JP 2023577531A JP 2023577531 A JP2023577531 A JP 2023577531A JP WO2022266396 A5 JPWO2022266396 A5 JP WO2022266396A5
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JP
Japan
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domain
seq
protease
optionally
amino acid
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Pending
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JP2023577531A
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English (en)
Japanese (ja)
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JP2024524922A5 (https=
JP2024524922A (ja
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Priority claimed from PCT/US2022/033893 external-priority patent/WO2022266396A1/en
Publication of JP2024524922A publication Critical patent/JP2024524922A/ja
Publication of JP2024524922A5 publication Critical patent/JP2024524922A5/ja
Publication of JPWO2022266396A5 publication Critical patent/JPWO2022266396A5/ja
Pending legal-status Critical Current

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JP2023577531A 2021-06-16 2022-06-16 武装化キメラ受容体及びその使用方法 Pending JP2024524922A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163211468P 2021-06-16 2021-06-16
US63/211,468 2021-06-16
US202263305155P 2022-01-31 2022-01-31
US63/305,155 2022-01-31
PCT/US2022/033893 WO2022266396A1 (en) 2021-06-16 2022-06-16 Armed chimeric receptors and methods of use thereof

Publications (3)

Publication Number Publication Date
JP2024524922A JP2024524922A (ja) 2024-07-09
JP2024524922A5 JP2024524922A5 (https=) 2024-08-06
JPWO2022266396A5 true JPWO2022266396A5 (https=) 2024-08-06

Family

ID=84526773

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023577531A Pending JP2024524922A (ja) 2021-06-16 2022-06-16 武装化キメラ受容体及びその使用方法

Country Status (9)

Country Link
US (1) US20240277766A1 (https=)
EP (1) EP4355341A4 (https=)
JP (1) JP2024524922A (https=)
KR (1) KR20240022575A (https=)
AU (1) AU2022294896A1 (https=)
CA (1) CA3221897A1 (https=)
IL (1) IL309161A (https=)
TW (1) TW202317753A (https=)
WO (1) WO2022266396A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12264189B2 (en) 2018-10-31 2025-04-01 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
WO2020092736A1 (en) 2018-10-31 2020-05-07 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
WO2024102943A1 (en) * 2022-11-09 2024-05-16 Senti Biosciences, Inc. Armed chimeric receptors and methods of use thereof
EP4619420A1 (en) * 2022-11-16 2025-09-24 Regeneron Pharmaceuticals, Inc. Chimeric proteins comprising membrane bound il-12 with protease cleavable linkers
WO2025106924A1 (en) * 2023-11-16 2025-05-22 Senti Biosciences, Inc. Methods of enhancing engineered immune cell cytotoxicity
WO2025179221A1 (en) * 2024-02-22 2025-08-28 Senti Biosciences, Inc. Compositions and methods for armored cell based therapies
WO2026077446A1 (en) * 2024-10-12 2026-04-16 Nanjing Legend Biotech Co., Ltd. Engineered il-15 constructs and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2794196A1 (en) * 2010-03-23 2011-09-29 Intrexon Corporation Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof
KR20190102259A (ko) * 2017-01-10 2019-09-03 인트렉손 코포레이션 신규의 유전자 스위치 발현 시스템을 통한 폴리펩티드의 발현 조절
KR20200056980A (ko) * 2017-07-12 2020-05-25 레퓨즈 바이오테크놀로지스, 인크. 유전자 발현의 조건부 조절을 위한 방법 및 시스템
EP3784256A4 (en) * 2018-04-27 2022-06-29 Baylor College of Medicine Car t cells with one or more interleukins
TWI809130B (zh) * 2018-06-22 2023-07-21 美商凱特製藥公司 嵌合跨膜蛋白及其用途
SG11202103317XA (en) * 2018-10-17 2021-05-28 Senti Biosciences Inc Combinatorial cancer immunotherapy
JP2022512450A (ja) * 2018-12-13 2022-02-03 カースゲン セラピューティクス カンパニー リミテッド Gpc3を標的とする免疫エフェクター細胞およびその応用
CA3138576A1 (en) * 2019-05-16 2020-11-19 Trustees Of Boston University Regulated synthetic gene expression systems
US20220396609A1 (en) * 2019-11-01 2022-12-15 Senti Biosciences, Inc. Chimeric receptor sensors
WO2021119539A1 (en) * 2019-12-12 2021-06-17 Senti Biosciences, Inc. Method and compositions for regulated armoring of cells
IL302568A (en) * 2020-11-04 2023-07-01 Senti Biosciences Inc Protein payload release

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