KR20240022575A - 아머링된 키메라 수용체 및 이의 사용 방법 - Google Patents

아머링된 키메라 수용체 및 이의 사용 방법 Download PDF

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Publication number
KR20240022575A
KR20240022575A KR1020247001340A KR20247001340A KR20240022575A KR 20240022575 A KR20240022575 A KR 20240022575A KR 1020247001340 A KR1020247001340 A KR 1020247001340A KR 20247001340 A KR20247001340 A KR 20247001340A KR 20240022575 A KR20240022575 A KR 20240022575A
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South Korea
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domain
protease
seq
optionally
peptidase
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Korean (ko)
Inventor
마르셀라 구즈만 아얄라
러셀 모리슨 골들리
미셸 엘리자베스 헝
개리 이
티모시 관-타 루
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센티 바이오사이언시스, 인코포레이티드
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Publication of KR20240022575A publication Critical patent/KR20240022575A/ko
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    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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KR1020247001340A 2021-06-16 2022-06-16 아머링된 키메라 수용체 및 이의 사용 방법 Pending KR20240022575A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163211468P 2021-06-16 2021-06-16
US63/211,468 2021-06-16
US202263305155P 2022-01-31 2022-01-31
US63/305,155 2022-01-31
PCT/US2022/033893 WO2022266396A1 (en) 2021-06-16 2022-06-16 Armed chimeric receptors and methods of use thereof

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KR20240022575A true KR20240022575A (ko) 2024-02-20

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US (1) US20240277766A1 (https=)
EP (1) EP4355341A4 (https=)
JP (1) JP2024524922A (https=)
KR (1) KR20240022575A (https=)
AU (1) AU2022294896A1 (https=)
CA (1) CA3221897A1 (https=)
IL (1) IL309161A (https=)
TW (1) TW202317753A (https=)
WO (1) WO2022266396A1 (https=)

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WO2020092736A1 (en) 2018-10-31 2020-05-07 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
WO2024102943A1 (en) * 2022-11-09 2024-05-16 Senti Biosciences, Inc. Armed chimeric receptors and methods of use thereof
EP4619420A1 (en) * 2022-11-16 2025-09-24 Regeneron Pharmaceuticals, Inc. Chimeric proteins comprising membrane bound il-12 with protease cleavable linkers
WO2025106924A1 (en) * 2023-11-16 2025-05-22 Senti Biosciences, Inc. Methods of enhancing engineered immune cell cytotoxicity
WO2025179221A1 (en) * 2024-02-22 2025-08-28 Senti Biosciences, Inc. Compositions and methods for armored cell based therapies
WO2026077446A1 (en) * 2024-10-12 2026-04-16 Nanjing Legend Biotech Co., Ltd. Engineered il-15 constructs and uses thereof

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