JPWO2021053344A5 - - Google Patents
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- Publication number
- JPWO2021053344A5 JPWO2021053344A5 JP2022516299A JP2022516299A JPWO2021053344A5 JP WO2021053344 A5 JPWO2021053344 A5 JP WO2021053344A5 JP 2022516299 A JP2022516299 A JP 2022516299A JP 2022516299 A JP2022516299 A JP 2022516299A JP WO2021053344 A5 JPWO2021053344 A5 JP WO2021053344A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- imidazol
- urea
- phenyl
- thienylsulfonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025186669A JP2026041728A (ja) | 2019-09-20 | 2025-11-05 | 新化合物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201913603A GB201913603D0 (en) | 2019-09-20 | 2019-09-20 | New compounds |
| GB1913603.5 | 2019-09-20 | ||
| PCT/GB2020/052261 WO2021053344A1 (en) | 2019-09-20 | 2020-09-18 | New compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025186669A Division JP2026041728A (ja) | 2019-09-20 | 2025-11-05 | 新化合物 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022549086A JP2022549086A (ja) | 2022-11-24 |
| JPWO2021053344A5 true JPWO2021053344A5 (https=) | 2023-09-06 |
| JP2022549086A5 JP2022549086A5 (https=) | 2023-09-06 |
| JP7771049B2 JP7771049B2 (ja) | 2025-11-17 |
Family
ID=68425648
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022516299A Active JP7771049B2 (ja) | 2019-09-20 | 2020-09-18 | 新化合物 |
| JP2025186669A Pending JP2026041728A (ja) | 2019-09-20 | 2025-11-05 | 新化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025186669A Pending JP2026041728A (ja) | 2019-09-20 | 2025-11-05 | 新化合物 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US12435072B2 (https=) |
| EP (1) | EP4031240A1 (https=) |
| JP (2) | JP7771049B2 (https=) |
| KR (1) | KR20220101071A (https=) |
| CN (1) | CN114786774A (https=) |
| AU (1) | AU2020351301B2 (https=) |
| BR (1) | BR112022003130A2 (https=) |
| CA (1) | CA3152218A1 (https=) |
| CL (1) | CL2022000656A1 (https=) |
| CO (1) | CO2022003091A2 (https=) |
| GB (1) | GB201913603D0 (https=) |
| IL (1) | IL291172A (https=) |
| MX (2) | MX2022003286A (https=) |
| PH (1) | PH12022550564A1 (https=) |
| WO (1) | WO2021053344A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202004094D0 (en) * | 2020-03-20 | 2020-05-06 | Vicore Pharma Ab | New compounds and uses |
| GB202013721D0 (en) * | 2020-09-01 | 2020-10-14 | Vicore Pharma Ab | New compounds |
| GB202104033D0 (en) * | 2021-03-23 | 2021-05-05 | Vicore Pharma Ab | New compounds |
| GB2605148A (en) * | 2021-03-23 | 2022-09-28 | Vicore Pharma Ab | New compounds |
| EP4313953A1 (en) * | 2021-03-23 | 2024-02-07 | Vicore Pharma AB | Selective angiotensin ii receptor ligands |
| GB202113583D0 (en) * | 2021-09-23 | 2021-11-10 | Vicore Pharma Ab | New compounds |
| GB202104038D0 (en) * | 2021-03-23 | 2021-05-05 | Vicore Pharma Ab | New compounds |
| MX2024000518A (es) * | 2021-07-09 | 2024-01-31 | Vicore Pharma Ab | Nuevos compuestos selectivos de angiotensina ii. |
| CA3247073A1 (en) * | 2022-04-06 | 2025-02-03 | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company | AT2R AGONIST |
| IE20230600A3 (en) | 2022-12-22 | 2025-09-24 | Vicore Pharma Ab | A method of treating a patient diagnosed with an interstitial lung disease |
| WO2024149712A1 (en) * | 2023-01-09 | 2024-07-18 | Vicore Pharma Ab | Selective angiotensin ii compounds |
| CN119504723A (zh) * | 2023-08-25 | 2025-02-25 | 武汉人福创新药物研发中心有限公司 | 作为at2r激动剂的噻吩磺酰基氨基甲酸酯 |
| WO2025146172A1 (zh) * | 2024-01-03 | 2025-07-10 | 武汉人福创新药物研发中心有限公司 | 一种并环类化合物作为at2r激动剂 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5198438A (en) * | 1991-05-07 | 1993-03-30 | Merck & Co., Inc. | Angiotensin ii antagonists incorporating a substituted thiophene or furan |
| US5312820A (en) | 1992-07-17 | 1994-05-17 | Merck & Co., Inc. | Substituted carbamoyl and oxycarbonyl derivatives of biphenylmethylamines |
| US5444067A (en) | 1993-08-30 | 1995-08-22 | Merck & Co., Inc. | Pharmaceutical treatment methods using angiotensin II receptor agonists bearing a thiophene moiety |
| SE9800550D0 (sv) | 1998-02-24 | 1998-02-24 | A & Science Invest Ab | A pharmaceutical preparation comprising an angiotensin II type 2 receptor agonist, and use thereof |
| YU78601A (sh) | 1999-05-05 | 2005-07-19 | Aventis Pharma Deutschland Gmbh. | 1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže |
| DE19920815A1 (de) | 1999-05-05 | 2000-11-09 | Aventis Pharma Gmbh | 1-(p-Thienylbenzyl)-Imidazole als Agonisten von Angiotensin-(1-7)-Rezeptoren, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| KR100938817B1 (ko) | 2001-05-31 | 2010-01-26 | 바이코어 파마 아베 | 안지오텐신 ⅱ 작용제로 유용한 삼중고리 화합물 |
| CA2449150C (en) | 2001-05-31 | 2011-07-12 | Vicore Pharma Ab | Tricyclic compounds useful as angiotensin ii agonists |
| WO2004046141A1 (en) | 2002-11-21 | 2004-06-03 | Vicore Pharma Ab | New tricyclic angiotensin ii agonists |
| AU2006235698B2 (en) | 2005-04-12 | 2012-03-29 | Vicore Pharma Ab | New tricyclic angiotensin II agonists |
| US8835471B2 (en) | 2010-06-11 | 2014-09-16 | Vicore Pharma Ab | Use of angiotensin II agonists |
| KR20150028761A (ko) * | 2011-12-16 | 2015-03-16 | 타릭스 파마슈티컬스 엘티디. | 섬유증 치료용 안지오텐신 |
| KR102230461B1 (ko) | 2013-03-15 | 2021-03-22 | 유니버시티 오브 써던 캘리포니아 | 엔지오텐신-관련 질환들의 치료를 위한 방법들, 화합물들 및 조성물들 |
| EP2832357A1 (en) | 2013-07-29 | 2015-02-04 | Charité - Universitätsmedizin Berlin | Selective AT2 receptor agonists for use in treatment of cachexia |
| BR112017012337A2 (pt) | 2014-12-12 | 2018-02-27 | Vicore Pharma Ab | Método para tratamento de doença falciforme, agonista do receptor at2, ou um sal farmaceuticamente aceitável, solvato ou pró- fármaco do mesmo, uso de um agonista do receptor at2, ou um sal farmaceuticamente aceitável, solvato ou pró-fármaco do mesmo, formulação farmacêutica, e, produto de combinação. |
| WO2016107879A2 (en) | 2014-12-30 | 2016-07-07 | Vicore Pharma Ab | New use of angiotensin ii receptor agonists |
| CN107405406A (zh) * | 2015-03-02 | 2017-11-28 | 维科尔药物公司 | 用于治疗肺纤维化的血管紧张素ii受体激动剂 |
| WO2017221012A1 (en) | 2016-06-21 | 2017-12-28 | Vicore Pharma Ab | Methods and compositions for preventing or reducing the risk of cancer treatment-related cardiotoxicity |
| AR108906A1 (es) * | 2016-06-29 | 2018-10-10 | Bristol Myers Squibb Co | Heterociclos de biarilmetilo |
| GB201710906D0 (en) | 2017-07-06 | 2017-08-23 | Vicore Pharma Ab | Compounds and methods for treating peripheral neuropathy |
-
2019
- 2019-09-20 GB GB201913603A patent/GB201913603D0/en not_active Ceased
-
2020
- 2020-09-18 WO PCT/GB2020/052261 patent/WO2021053344A1/en not_active Ceased
- 2020-09-18 CN CN202080065335.5A patent/CN114786774A/zh active Pending
- 2020-09-18 AU AU2020351301A patent/AU2020351301B2/en active Active
- 2020-09-18 PH PH1/2022/550564A patent/PH12022550564A1/en unknown
- 2020-09-18 EP EP20780297.6A patent/EP4031240A1/en active Pending
- 2020-09-18 BR BR112022003130A patent/BR112022003130A2/pt unknown
- 2020-09-18 MX MX2022003286A patent/MX2022003286A/es unknown
- 2020-09-18 US US17/761,670 patent/US12435072B2/en active Active
- 2020-09-18 KR KR1020227008929A patent/KR20220101071A/ko active Pending
- 2020-09-18 CA CA3152218A patent/CA3152218A1/en active Pending
- 2020-09-18 JP JP2022516299A patent/JP7771049B2/ja active Active
-
2022
- 2022-03-07 IL IL291172A patent/IL291172A/en unknown
- 2022-03-17 CL CL2022000656A patent/CL2022000656A1/es unknown
- 2022-03-17 MX MX2025000262A patent/MX2025000262A/es unknown
- 2022-03-17 CO CONC2022/0003091A patent/CO2022003091A2/es unknown
-
2025
- 2025-10-02 US US19/348,124 patent/US20260028333A1/en active Pending
- 2025-11-05 JP JP2025186669A patent/JP2026041728A/ja active Pending
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