JP2022549086A5 - - Google Patents
Info
- Publication number
- JP2022549086A5 JP2022549086A5 JP2022516299A JP2022516299A JP2022549086A5 JP 2022549086 A5 JP2022549086 A5 JP 2022549086A5 JP 2022516299 A JP2022516299 A JP 2022516299A JP 2022516299 A JP2022516299 A JP 2022516299A JP 2022549086 A5 JP2022549086 A5 JP 2022549086A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- imidazole
- urea
- phenyl
- thienylsulfonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025186669A JP2026041728A (ja) | 2019-09-20 | 2025-11-05 | 新化合物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1913603.5 | 2019-09-20 | ||
| GB201913603A GB201913603D0 (en) | 2019-09-20 | 2019-09-20 | New compounds |
| PCT/GB2020/052261 WO2021053344A1 (en) | 2019-09-20 | 2020-09-18 | New compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025186669A Division JP2026041728A (ja) | 2019-09-20 | 2025-11-05 | 新化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022549086A JP2022549086A (ja) | 2022-11-24 |
| JP2022549086A5 true JP2022549086A5 (https=) | 2023-09-06 |
| JP7771049B2 JP7771049B2 (ja) | 2025-11-17 |
Family
ID=68425648
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022516299A Active JP7771049B2 (ja) | 2019-09-20 | 2020-09-18 | 新化合物 |
| JP2025186669A Pending JP2026041728A (ja) | 2019-09-20 | 2025-11-05 | 新化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025186669A Pending JP2026041728A (ja) | 2019-09-20 | 2025-11-05 | 新化合物 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US12435072B2 (https=) |
| EP (1) | EP4031240A1 (https=) |
| JP (2) | JP7771049B2 (https=) |
| KR (1) | KR20220101071A (https=) |
| CN (1) | CN114786774A (https=) |
| AU (1) | AU2020351301B2 (https=) |
| BR (1) | BR112022003130A2 (https=) |
| CA (1) | CA3152218A1 (https=) |
| CL (1) | CL2022000656A1 (https=) |
| CO (1) | CO2022003091A2 (https=) |
| GB (1) | GB201913603D0 (https=) |
| IL (1) | IL291172A (https=) |
| MX (2) | MX2022003286A (https=) |
| PH (1) | PH12022550564A1 (https=) |
| WO (1) | WO2021053344A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202004094D0 (en) * | 2020-03-20 | 2020-05-06 | Vicore Pharma Ab | New compounds and uses |
| GB202013721D0 (en) * | 2020-09-01 | 2020-10-14 | Vicore Pharma Ab | New compounds |
| GB202104033D0 (en) * | 2021-03-23 | 2021-05-05 | Vicore Pharma Ab | New compounds |
| CA3212900A1 (en) * | 2021-03-23 | 2022-09-29 | Tomas Fex | Selective angiotensin ii receptor ligands |
| GB202104038D0 (en) * | 2021-03-23 | 2021-05-05 | Vicore Pharma Ab | New compounds |
| GB2605148A (en) * | 2021-03-23 | 2022-09-28 | Vicore Pharma Ab | New compounds |
| GB202113583D0 (en) * | 2021-09-23 | 2021-11-10 | Vicore Pharma Ab | New compounds |
| KR20240035402A (ko) | 2021-07-09 | 2024-03-15 | 바이코어 파마 아베 | 신규의 선택적 안지오텐신 ii 화합물 |
| US20250214978A1 (en) * | 2022-04-06 | 2025-07-03 | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company | At2r agonist |
| IE20230600A3 (en) | 2022-12-22 | 2025-09-24 | Vicore Pharma Ab | A method of treating a patient diagnosed with an interstitial lung disease |
| EP4648850A1 (en) * | 2023-01-09 | 2025-11-19 | Vicore Pharma AB | Selective angiotensin ii compounds |
| AU2024331772A1 (en) * | 2023-08-25 | 2026-04-02 | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. | Thienylsulfonyl carbamates as at2r agonists |
| CN120247885A (zh) * | 2024-01-03 | 2025-07-04 | 武汉人福创新药物研发中心有限公司 | 一种并环类化合物作为at2r激动剂 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5198438A (en) * | 1991-05-07 | 1993-03-30 | Merck & Co., Inc. | Angiotensin ii antagonists incorporating a substituted thiophene or furan |
| US5312820A (en) | 1992-07-17 | 1994-05-17 | Merck & Co., Inc. | Substituted carbamoyl and oxycarbonyl derivatives of biphenylmethylamines |
| US5444067A (en) | 1993-08-30 | 1995-08-22 | Merck & Co., Inc. | Pharmaceutical treatment methods using angiotensin II receptor agonists bearing a thiophene moiety |
| SE9800550D0 (sv) | 1998-02-24 | 1998-02-24 | A & Science Invest Ab | A pharmaceutical preparation comprising an angiotensin II type 2 receptor agonist, and use thereof |
| DE19920815A1 (de) | 1999-05-05 | 2000-11-09 | Aventis Pharma Gmbh | 1-(p-Thienylbenzyl)-Imidazole als Agonisten von Angiotensin-(1-7)-Rezeptoren, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| YU78601A (sh) * | 1999-05-05 | 2005-07-19 | Aventis Pharma Deutschland Gmbh. | 1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže |
| CN1529697B (zh) | 2001-05-31 | 2010-09-22 | 维科尔药物公司 | 用作血管紧张素ⅱ激动剂的三环化合物 |
| JP4707321B2 (ja) * | 2001-05-31 | 2011-06-22 | ヴィコール・ファルマ・アーベー | アンギオテンシンｉｉアゴニストとして有用な三環式化合物 |
| AU2003302106A1 (en) | 2002-11-21 | 2004-06-15 | Vicore Pharma Ab | New tricyclic angiotensin ii agonists |
| DK1869023T3 (da) * | 2005-04-12 | 2012-04-10 | Vicore Pharma Ab | Nye tricykliske angiotensin-II-agonister |
| US8835471B2 (en) | 2010-06-11 | 2014-09-16 | Vicore Pharma Ab | Use of angiotensin II agonists |
| CN104302305A (zh) * | 2011-12-16 | 2015-01-21 | 塔瑞克斯制药有限公司 | 用于治疗纤维化的血管紧张素 |
| EP3935944A1 (en) | 2013-03-15 | 2022-01-12 | University Of Southern California, USC Stevens | Compounds for the treatment of musculoskeletal diseases |
| EP2832357A1 (en) | 2013-07-29 | 2015-02-04 | Charité - Universitätsmedizin Berlin | Selective AT2 receptor agonists for use in treatment of cachexia |
| BR112017012337A2 (pt) | 2014-12-12 | 2018-02-27 | Vicore Pharma Ab | Método para tratamento de doença falciforme, agonista do receptor at2, ou um sal farmaceuticamente aceitável, solvato ou pró- fármaco do mesmo, uso de um agonista do receptor at2, ou um sal farmaceuticamente aceitável, solvato ou pró-fármaco do mesmo, formulação farmacêutica, e, produto de combinação. |
| WO2016107879A2 (en) | 2014-12-30 | 2016-07-07 | Vicore Pharma Ab | New use of angiotensin ii receptor agonists |
| EP3265082A1 (en) | 2015-03-02 | 2018-01-10 | Vicore Pharma AB | Angiotensin ii receptor agonist for treating pulmonary fibrosis |
| WO2017221012A1 (en) | 2016-06-21 | 2017-12-28 | Vicore Pharma Ab | Methods and compositions for preventing or reducing the risk of cancer treatment-related cardiotoxicity |
| ES2984389T3 (es) * | 2016-06-29 | 2024-10-29 | Univ Montreal | Heterociclos de biarilmetilo |
| GB201710906D0 (en) | 2017-07-06 | 2017-08-23 | Vicore Pharma Ab | Compounds and methods for treating peripheral neuropathy |
-
2019
- 2019-09-20 GB GB201913603A patent/GB201913603D0/en not_active Ceased
-
2020
- 2020-09-18 PH PH1/2022/550564A patent/PH12022550564A1/en unknown
- 2020-09-18 MX MX2022003286A patent/MX2022003286A/es unknown
- 2020-09-18 AU AU2020351301A patent/AU2020351301B2/en active Active
- 2020-09-18 JP JP2022516299A patent/JP7771049B2/ja active Active
- 2020-09-18 EP EP20780297.6A patent/EP4031240A1/en active Pending
- 2020-09-18 KR KR1020227008929A patent/KR20220101071A/ko active Pending
- 2020-09-18 CA CA3152218A patent/CA3152218A1/en active Pending
- 2020-09-18 US US17/761,670 patent/US12435072B2/en active Active
- 2020-09-18 CN CN202080065335.5A patent/CN114786774A/zh active Pending
- 2020-09-18 BR BR112022003130A patent/BR112022003130A2/pt unknown
- 2020-09-18 WO PCT/GB2020/052261 patent/WO2021053344A1/en not_active Ceased
-
2022
- 2022-03-07 IL IL291172A patent/IL291172A/en unknown
- 2022-03-17 MX MX2025000262A patent/MX2025000262A/es unknown
- 2022-03-17 CO CONC2022/0003091A patent/CO2022003091A2/es unknown
- 2022-03-17 CL CL2022000656A patent/CL2022000656A1/es unknown
-
2025
- 2025-10-02 US US19/348,124 patent/US20260028333A1/en active Pending
- 2025-11-05 JP JP2025186669A patent/JP2026041728A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022549086A5 (https=) | ||
| JP2018535999A5 (https=) | ||
| JP2022191517A5 (https=) | ||
| JP2019518036A5 (https=) | ||
| JP2014511869A5 (https=) | ||
| JP2023539614A5 (https=) | ||
| JP2004524301A5 (https=) | ||
| JP2010504280A5 (https=) | ||
| JP2007502264A5 (https=) | ||
| JP2009525340A5 (https=) | ||
| JP2020516671A5 (https=) | ||
| JP2013531070A5 (https=) | ||
| JP2007517010A5 (https=) | ||
| JP2005505551A (ja) | Ｃｂ１受容体拮抗剤と脳内のドパミン作用性神経伝達を活性化する生成物を含む、パーキンソン病の治療のための組成物 | |
| JP2007508346A5 (https=) | ||
| JP2005538955A5 (https=) | ||
| JP2005511543A5 (https=) | ||
| JP2004511469A5 (https=) | ||
| RU2008141509A (ru) | Mglur5 модуляторы 1 | |
| RU2013138569A (ru) | Антагонисты рецептора минералокортикоидов | |
| JP2007511485A5 (https=) | ||
| JP2023518474A5 (https=) | ||
| JP2024528036A5 (https=) | ||
| JP2007519695A5 (https=) | ||
| JP2006506380A5 (https=) |