JPWO2020247447A5 - - Google Patents
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- JPWO2020247447A5 JPWO2020247447A5 JP2021569992A JP2021569992A JPWO2020247447A5 JP WO2020247447 A5 JPWO2020247447 A5 JP WO2020247447A5 JP 2021569992 A JP2021569992 A JP 2021569992A JP 2021569992 A JP2021569992 A JP 2021569992A JP WO2020247447 A5 JPWO2020247447 A5 JP WO2020247447A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- halogen
- substituted
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962856822P | 2019-06-04 | 2019-06-04 | |
| US62/856,822 | 2019-06-04 | ||
| PCT/US2020/035851 WO2020247447A1 (en) | 2019-06-04 | 2020-06-03 | Pyrazole and imidazole derivatives, compositions and methods as orexin antagonists |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022534709A JP2022534709A (ja) | 2022-08-03 |
| JP2022534709A5 JP2022534709A5 (https=) | 2023-06-08 |
| JPWO2020247447A5 true JPWO2020247447A5 (https=) | 2023-06-08 |
| JP7837120B2 JP7837120B2 (ja) | 2026-03-30 |
Family
ID=73651984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021569992A Active JP7837120B2 (ja) | 2019-06-04 | 2020-06-03 | オレキシンアンタゴニストとしてのピラゾール及びイミダゾール誘導体、組成物、並びに方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20220315602A1 (https=) |
| EP (1) | EP3972587A4 (https=) |
| JP (1) | JP7837120B2 (https=) |
| KR (1) | KR20220016919A (https=) |
| CN (1) | CN114340616A (https=) |
| AU (1) | AU2020288559C1 (https=) |
| CA (1) | CA3140173A1 (https=) |
| SG (1) | SG11202112828SA (https=) |
| WO (1) | WO2020247447A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114286675A (zh) * | 2019-06-04 | 2022-04-05 | 海格生物科学有限责任公司 | 作为食欲肽拮抗剂的咪唑衍生物、组合物以及方法 |
| AU2020407664A1 (en) | 2019-12-20 | 2022-08-18 | Tenaya Therapeutics, Inc. | Fluoroalkyl-oxadiazoles and uses thereof |
| AU2022270657A1 (en) | 2021-05-04 | 2023-11-16 | Tenaya Therapeutics, Inc. | 2-fluoroalkyl-1,3,4-oxadiazol-5-yl-thiazol, hdac6 inhibitors for use in the treatment of metabolic disease and hfpef |
| US20260070922A1 (en) * | 2022-09-01 | 2026-03-12 | Hager Biosciences, Llc | Pyrazole and imidazole derivatives as dual orexin and kappa-opioid receptors modulators composition, methods for treating neurological and psychiatric disorders |
| US20250188095A1 (en) * | 2022-11-23 | 2025-06-12 | Jiangsu Nhwa Pharmaceutical Co., Ltd | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-c]PYRROLYL METHYL KETONE DERIVATIVE AND USE THEREOF |
| GB202311280D0 (en) | 2023-07-21 | 2023-09-06 | Bial Portela & Ca Sa | Orexin receptor antagonists |
| GB202311281D0 (en) | 2023-07-21 | 2023-09-06 | Bial Portela & Ca Sa | Orexin receptor antagonists |
| CN117169393B (zh) * | 2023-11-03 | 2024-03-19 | 杭州湃肽生化科技有限公司 | 一种植物组织中环肽的检测方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4925849A (en) * | 1987-06-15 | 1990-05-15 | Fujisawa Pharmaceutical Company, Ltd. | Pharmaceutically useful pyrazolopyridines |
| UA85937C2 (uk) * | 2004-12-21 | 2009-03-10 | Пфайзер Продактс Інк. | Макроліди |
| AR067665A1 (es) * | 2007-07-27 | 2009-10-21 | Actelion Pharmaceuticals Ltd | Derivados de trans-3- aza-biciclo ( 3.1.0) hexano |
| UA109457C2 (ru) * | 2010-10-21 | 2015-08-25 | Байєр Інтелекчуал Проперті Гмбх | 1-(гетероциклический карбонил)-2-замещенные пирролидины |
| EP2730573A4 (en) * | 2011-07-05 | 2014-12-03 | Taisho Pharmaceutical Co Ltd | METHYLPIPERIDINDERIVAT |
| WO2013062858A1 (en) * | 2011-10-25 | 2013-05-02 | Merck Sharp & Dohme Corp. | Isoxazolopyridine orexin receptor antagonists |
| ES2672732T3 (es) * | 2012-02-07 | 2018-06-15 | Eolas Therapeutics Inc. | Prolinas/piperidinas sustituidas como antagonistas del receptor de orexina |
| US10081624B2 (en) * | 2014-08-26 | 2018-09-25 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| EP3856178B1 (en) * | 2018-09-28 | 2026-03-11 | Janssen Pharmaceutica NV | Monoacylglycerol lipase modulators |
| CN114286675A (zh) * | 2019-06-04 | 2022-04-05 | 海格生物科学有限责任公司 | 作为食欲肽拮抗剂的咪唑衍生物、组合物以及方法 |
-
2020
- 2020-06-03 US US17/616,142 patent/US20220315602A1/en not_active Abandoned
- 2020-06-03 EP EP20817900.2A patent/EP3972587A4/en not_active Withdrawn
- 2020-06-03 AU AU2020288559A patent/AU2020288559C1/en not_active Expired - Fee Related
- 2020-06-03 WO PCT/US2020/035851 patent/WO2020247447A1/en not_active Ceased
- 2020-06-03 CN CN202080056013.4A patent/CN114340616A/zh active Pending
- 2020-06-03 JP JP2021569992A patent/JP7837120B2/ja active Active
- 2020-06-03 SG SG11202112828SA patent/SG11202112828SA/en unknown
- 2020-06-03 CA CA3140173A patent/CA3140173A1/en active Pending
- 2020-06-03 KR KR1020217043401A patent/KR20220016919A/ko not_active Ceased
-
2024
- 2024-08-09 US US18/799,706 patent/US12275744B2/en active Active
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