|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
FR2656800B1
(fr)
|
1990-01-08 |
1992-05-15 |
Roussy Inst Gustave |
Nouvelles proteines produits par les lymphocytes humains, sequence d'adn codant pour ces proteines et applications pharmaceutiques et biologiques.
|
|
US5976877A
(en)
|
1990-01-08 |
1999-11-02 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Proteins produced by human lymphocytes DNA sequence encoding these proteins and their pharmaceutical and biological uses
|
|
US5932448A
(en)
|
1991-11-29 |
1999-08-03 |
Protein Design Labs., Inc. |
Bispecific antibody heterodimers
|
|
US6129914A
(en)
|
1992-03-27 |
2000-10-10 |
Protein Design Labs, Inc. |
Bispecific antibody effective to treat B-cell lymphoma and cell line
|
|
JP3700859B2
(ja)
|
1994-05-06 |
2005-09-28 |
アンスティテュ ギュスタブ ルシ |
Ｌａｇ−３タンパク質の可溶性ポリペプチドフラクション；製造方法、治療用製剤、抗イディオタイプ抗体
|
|
US5532210A
(en)
|
1994-06-08 |
1996-07-02 |
E. I. Du Pont De Nemours And Company |
High temperature superconductor dielectric slow wave structures for accelerators and traveling wave tubes
|
|
IL122832A
(en)
|
1995-07-21 |
2006-08-20 |
Inst Nat Sante Rech Med |
Methods for detecting, identifying , isolating and selectively labeling and targeting th1 lymphocytes by means of the lag-3 protein
|
|
EP0900841A1
(en)
|
1997-06-18 |
1999-03-10 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
LAG-3 splice variants
|
|
MXPA01005515A
(es)
|
1998-12-01 |
2003-07-14 |
Protein Design Labs Inc |
Anticuerpos humanizados para gamma-interferon.
|
|
US7087411B2
(en)
|
1999-06-08 |
2006-08-08 |
Regeneron Pharmaceuticals, Inc. |
Fusion protein capable of binding VEGF
|
|
WO2001014557A1
(en)
|
1999-08-23 |
2001-03-01 |
Dana-Farber Cancer Institute, Inc. |
Pd-1, a receptor for b7-4, and uses therefor
|
|
ES2367430T3
(es)
|
2002-12-23 |
2011-11-03 |
Wyeth Llc |
Anticuerpos contra pd-1 y sus usos.
|
|
AU2004217526B2
(en)
|
2003-02-28 |
2010-02-04 |
St. Jude Children's Research Hospital Inc. |
T cell regulation
|
|
PT2767161T
(pt)
|
2004-10-19 |
2018-04-20 |
Regeneron Pharma |
Método para gerar um animal homozigótico para uma modificação genética
|
|
ES2427646T5
(es)
|
2005-05-09 |
2017-08-22 |
Ono Pharmaceutical Co., Ltd. |
Anticuerpos monoclonales humanos contra muerte programada 1 (PD1) y métodos para el tratamiento del cáncer mediante el uso de anticuerpos anti-PD-1 solos o combinados con otros agentes inmunoterapéuticos
|
|
US9244059B2
(en)
|
2007-04-30 |
2016-01-26 |
Immutep Parc Club Orsay |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
|
EP1987839A1
(en)
|
2007-04-30 |
2008-11-05 |
I.N.S.E.R.M. Institut National de la Sante et de la Recherche Medicale |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
|
RS53072B
(en)
|
2007-06-18 |
2014-04-30 |
Merck Sharp & Dohme B.V. |
HUMAN RECEPTOR ANTIBODIES PROGRAMMED DEATH PD-1
|
|
PT2242773T
(pt)
|
2008-02-11 |
2017-09-15 |
Cure Tech Ltd |
Anticorpos monoclonais para o tratamento de tumores
|
|
EP2262837A4
(en)
|
2008-03-12 |
2011-04-06 |
Merck Sharp & Dohme |
PD-1 BINDING PROTEINS
|
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
|
WO2010027423A2
(en)
|
2008-08-25 |
2010-03-11 |
Amplimmune, Inc. |
Compositions of pd-1 antagonists and methods of use
|
|
US20130017199A1
(en)
|
2009-11-24 |
2013-01-17 |
AMPLIMMUNE ,Inc. a corporation |
Simultaneous inhibition of pd-l1/pd-l2
|
|
MX338353B
(es)
|
2011-04-20 |
2016-04-13 |
Medimmune Llc |
Anticuerpos y otras moleculas que se unen a b7 - h1 y pd - 1.
|
|
US8686119B2
(en)
|
2011-07-24 |
2014-04-01 |
Curetech Ltd. |
Variants of humanized immunomodulatory monoclonal antibodies
|
|
UY34887A
(es)
|
2012-07-02 |
2013-12-31 |
Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware |
Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
|
|
EP2970464B1
(en)
|
2013-03-15 |
2020-05-06 |
GlaxoSmithKline Intellectual Property Development Limited |
Anti-lag-3 binding proteins
|
|
RS64268B1
(sr)
*
|
2013-09-20 |
2023-07-31 |
Bristol Myers Squibb Co |
Kombinacija anti-lag-3 antitela i anti-pd-1 antitela za lečenje tumora
|
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對ｐｄ-１的人類抗體
|
|
DK3254110T3
(da)
|
2015-02-03 |
2020-05-18 |
Ventana Med Syst Inc |
Histokemisk test til vurdering af ekspression af programmeret død-ligand 1 (pd-l1)
|
|
US20180155429A1
(en)
|
2015-05-28 |
2018-06-07 |
Bristol-Myers Squibb Company |
Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody
|
|
WO2017037203A1
(en)
|
2015-09-02 |
2017-03-09 |
Immutep S.A.S. |
Anti-LAG-3 Antibodies
|
|
TWI756187B
(zh)
*
|
2015-10-09 |
2022-03-01 |
美商再生元醫藥公司 |
抗ｌａｇ３抗體及其用途
|
|
TW202408578A
(zh)
*
|
2016-05-13 |
2024-03-01 |
美商再生元醫藥公司 |
藉由投予pd-1抑制劑治療皮膚癌之方法
|
|
EA201892616A1
(ru)
*
|
2016-05-18 |
2019-05-31 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Антитела к pd1 и lag3 для лечения злокачественного новообразования
|
|
KR20230133934A
(ko)
|
2016-10-11 |
2023-09-19 |
아게누스 인코포레이티드 |
항-lag-3 항체 및 이의 사용 방법
|
|
AU2017342071A1
(en)
|
2016-10-13 |
2019-04-18 |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd |
Anti-LAG-3 antibodies and compositions
|
|
CA3045466A1
(en)
|
2016-12-01 |
2018-06-07 |
Regeneron Pharmaceuticals, Inc. |
Radiolabeled anti-pd-l1 antibodies for immuno-pet imaging
|
|
AU2018219909A1
(en)
|
2017-02-10 |
2019-09-12 |
Regeneron Pharmaceuticals, Inc. |
Radiolabeled anti-LAG3 antibodies for immuno-PET imaging
|
|
KR20220083863A
(ko)
*
|
2017-04-05 |
2022-06-20 |
심포젠 에이/에스 |
Pd-1, tim-3 및 lag-3을 표적화하는 조합 요법
|