JPWO2020150350A5 - - Google Patents

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Publication number
JPWO2020150350A5
JPWO2020150350A5 JP2021541244A JP2021541244A JPWO2020150350A5 JP WO2020150350 A5 JPWO2020150350 A5 JP WO2020150350A5 JP 2021541244 A JP2021541244 A JP 2021541244A JP 2021541244 A JP2021541244 A JP 2021541244A JP WO2020150350 A5 JPWO2020150350 A5 JP WO2020150350A5
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JP
Japan
Prior art keywords
sulfated
sulfotransferase
sulfate
nucleic acid
sulfotransferase enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021541244A
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English (en)
Japanese (ja)
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JP2022523638A (ja
JP2022523638A5 (https=
Publication date
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Priority claimed from PCT/US2020/013677 external-priority patent/WO2020150350A1/en
Publication of JP2022523638A publication Critical patent/JP2022523638A/ja
Publication of JPWO2020150350A5 publication Critical patent/JPWO2020150350A5/ja
Publication of JP2022523638A5 publication Critical patent/JP2022523638A5/ja
Pending legal-status Critical Current

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JP2021541244A 2019-01-15 2020-01-15 改変型硫酸アリール依存性酵素 Pending JP2022523638A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962792440P 2019-01-15 2019-01-15
US62/792,440 2019-01-15
US201962797466P 2019-01-28 2019-01-28
US62/797,466 2019-01-28
US201962808074P 2019-02-20 2019-02-20
US62/808,074 2019-02-20
US201962853261P 2019-05-28 2019-05-28
US62/853,261 2019-05-28
PCT/US2020/013677 WO2020150350A1 (en) 2019-01-15 2020-01-15 Engineered aryl sulfate-dependent enzymes

Publications (3)

Publication Number Publication Date
JP2022523638A JP2022523638A (ja) 2022-04-26
JPWO2020150350A5 true JPWO2020150350A5 (https=) 2023-01-20
JP2022523638A5 JP2022523638A5 (https=) 2023-01-20

Family

ID=69529057

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021541244A Pending JP2022523638A (ja) 2019-01-15 2020-01-15 改変型硫酸アリール依存性酵素

Country Status (10)

Country Link
US (9) US11692180B2 (https=)
EP (1) EP3911737A1 (https=)
JP (1) JP2022523638A (https=)
KR (1) KR20210126019A (https=)
CN (1) CN113646427A (https=)
AU (1) AU2020209822A1 (https=)
BR (1) BR112021013890A2 (https=)
CA (1) CA3126805A1 (https=)
MX (1) MX2021008479A (https=)
WO (1) WO2020150350A1 (https=)

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* Cited by examiner, † Cited by third party
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CN113646427A (zh) * 2019-01-15 2021-11-12 奥普蒂姆维亚有限公司 工程化芳基硫酸酯依赖性酶
WO2022015794A1 (en) 2020-07-14 2022-01-20 Optimvia, Llc Methods for synthesizing non-anticoagulant heparan sulfate
CA3144968A1 (en) * 2019-07-09 2021-01-14 Optimvia Llc Methods for synthesizing anticoagulant polysaccharides
CN114763570B (zh) * 2021-09-10 2024-02-27 江南大学 制备不同分子量肝素的磺酸化修饰体系构建及其应用
CN117467632B (zh) * 2022-07-27 2024-09-24 江南大学 一种肝素n-磺基转移酶突变体构建方法
CN115975040B (zh) * 2022-07-28 2026-02-27 重庆东渝中能实业有限公司 埃氏拟杆菌肝素酶i融合蛋白及其编码基因和制备方法
CN119662591B (zh) * 2025-01-20 2025-11-04 江南大学 一种肝素2-o-磺基转移酶高活性突变体的构建方法

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CN113646427A (zh) * 2019-01-15 2021-11-12 奥普蒂姆维亚有限公司 工程化芳基硫酸酯依赖性酶
US11708593B2 (en) * 2019-01-15 2023-07-25 Optimvia, Llc Engineered aryl sulfate-dependent enzymes

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