JPWO2020139764A5 - - Google Patents
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- Publication number
- JPWO2020139764A5 JPWO2020139764A5 JP2021538378A JP2021538378A JPWO2020139764A5 JP WO2020139764 A5 JPWO2020139764 A5 JP WO2020139764A5 JP 2021538378 A JP2021538378 A JP 2021538378A JP 2021538378 A JP2021538378 A JP 2021538378A JP WO2020139764 A5 JPWO2020139764 A5 JP WO2020139764A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- set forth
- sequence set
- positions
- antisense strand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024067819A JP2024105308A (ja) | 2018-12-28 | 2024-04-18 | Ｈｍｇｂ１発現を阻害するための組成物及び方法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862786287P | 2018-12-28 | 2018-12-28 | |
| US62/786,287 | 2018-12-28 | ||
| US201862787038P | 2018-12-31 | 2018-12-31 | |
| US62/787,038 | 2018-12-31 | ||
| US201962788111P | 2019-01-03 | 2019-01-03 | |
| US62/788,111 | 2019-01-03 | ||
| PCT/US2019/067883 WO2020139764A1 (en) | 2018-12-28 | 2019-12-20 | Compositions and methods for inhibiting hmgb1 expression |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024067819A Division JP2024105308A (ja) | 2018-12-28 | 2024-04-18 | Ｈｍｇｂ１発現を阻害するための組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022517742A JP2022517742A (ja) | 2022-03-10 |
| JPWO2020139764A5 true JPWO2020139764A5 (https=) | 2023-02-24 |
| JP2022517742A5 JP2022517742A5 (https=) | 2023-02-24 |
Family
ID=71128894
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021538378A Pending JP2022517742A (ja) | 2018-12-28 | 2019-12-20 | Ｈｍｇｂ１発現を阻害するための組成物及び方法 |
| JP2024067819A Withdrawn JP2024105308A (ja) | 2018-12-28 | 2024-04-18 | Ｈｍｇｂ１発現を阻害するための組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024067819A Withdrawn JP2024105308A (ja) | 2018-12-28 | 2024-04-18 | Ｈｍｇｂ１発現を阻害するための組成物及び方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20220072024A1 (https=) |
| EP (1) | EP3883581A4 (https=) |
| JP (2) | JP2022517742A (https=) |
| KR (1) | KR20210126004A (https=) |
| CN (1) | CN113874025A (https=) |
| AU (1) | AU2019417585A1 (https=) |
| BR (1) | BR112021012516A2 (https=) |
| CA (1) | CA3124664A1 (https=) |
| CL (2) | CL2021001718A1 (https=) |
| IL (2) | IL284327B2 (https=) |
| MX (1) | MX2021007855A (https=) |
| SG (1) | SG11202106857VA (https=) |
| WO (1) | WO2020139764A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20200023427A (ko) | 2017-06-29 | 2020-03-04 | 다이서나 파마수이티컬, 인크. | Hmgb1 발현을 억제하기 위한 조성물 및 방법 |
| WO2023208023A1 (zh) * | 2022-04-26 | 2023-11-02 | 上海拓界生物医药科技有限公司 | 氘代化学修饰和包含其的寡核苷酸 |
| TWI868755B (zh) | 2022-06-24 | 2025-01-01 | 丹麥商諾佛 儂迪克股份有限公司 | 抑制跨膜絲胺酸蛋白酶６（ｔｍｐｒｓｓ６）表現的組成物及方法 |
| CN117264954A (zh) * | 2022-09-20 | 2023-12-22 | 北京福元医药股份有限公司 | 用于抑制hmgb1基因表达的双链核糖核酸及其修饰物、缀合物和用途 |
| WO2024233864A2 (en) * | 2023-05-10 | 2024-11-14 | Dicerna Pharmaceuticals, Inc. | Galnac-conjugated rnai oligonucleotides |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007076200A2 (en) * | 2005-11-28 | 2007-07-05 | Medimmune, Inc. | Antagonists of hmgb1 and/or rage and methods of use thereof |
| WO2007150071A1 (en) * | 2006-06-23 | 2007-12-27 | Myriad Genetics, Inc. | Gene amplifications and deletions |
| US9278108B2 (en) * | 2009-07-16 | 2016-03-08 | Nec Solution Innovators, Ltd. | HMGB1 binding nucleic acid molecule and applications thereof |
| WO2012036215A1 (ja) * | 2010-09-17 | 2012-03-22 | Taniguchi Tadatsugu | Ｈｍｇｂタンパクによって仲介される免疫応答の活性化の抑制剤及びスクリーニング方法 |
| WO2012177639A2 (en) * | 2011-06-22 | 2012-12-27 | Alnylam Pharmaceuticals, Inc. | Bioprocessing and bioproduction using avian cell lines |
| AU2015330670B2 (en) * | 2014-10-10 | 2022-01-06 | Novo Nordisk Health Care Ag | Therapeutic inhibition of lactate dehydrogenase and agents therefor |
| JP7105065B2 (ja) * | 2014-12-15 | 2022-07-22 | ダイセルナ ファーマシューティカルズ， インコーポレイテッド | リガンド修飾二本鎖核酸 |
| WO2017079227A1 (en) * | 2015-11-05 | 2017-05-11 | University Of Connecticut | Compositions and methods for the treatment of liver fibrosis |
| KR102350647B1 (ko) * | 2016-09-02 | 2022-01-14 | 다이서나 파마수이티컬, 인크. | 4'-포스페이트 유사체 및 이를 포함하는 올리고뉴클레오타이드 |
| KR20200023427A (ko) * | 2017-06-29 | 2020-03-04 | 다이서나 파마수이티컬, 인크. | Hmgb1 발현을 억제하기 위한 조성물 및 방법 |
| JP2021508491A (ja) * | 2017-12-18 | 2021-03-11 | アルナイラム ファーマシューティカルズ， インコーポレイテッドＡｌｎｙｌａｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 高移動度グループボックス−１（ＨＭＧＢ１）ｉＲＮＡ組成物及びその使用方法 |
-
2019
- 2019-12-20 MX MX2021007855A patent/MX2021007855A/es unknown
- 2019-12-20 AU AU2019417585A patent/AU2019417585A1/en not_active Withdrawn
- 2019-12-20 BR BR112021012516-7A patent/BR112021012516A2/pt not_active Application Discontinuation
- 2019-12-20 US US17/309,860 patent/US20220072024A1/en not_active Abandoned
- 2019-12-20 WO PCT/US2019/067883 patent/WO2020139764A1/en not_active Ceased
- 2019-12-20 KR KR1020217023455A patent/KR20210126004A/ko not_active Withdrawn
- 2019-12-20 JP JP2021538378A patent/JP2022517742A/ja active Pending
- 2019-12-20 EP EP19902219.5A patent/EP3883581A4/en not_active Withdrawn
- 2019-12-20 CA CA3124664A patent/CA3124664A1/en active Pending
- 2019-12-20 IL IL284327A patent/IL284327B2/en unknown
- 2019-12-20 IL IL313425A patent/IL313425A/en unknown
- 2019-12-20 CN CN201980093263.2A patent/CN113874025A/zh not_active Withdrawn
- 2019-12-20 SG SG11202106857VA patent/SG11202106857VA/en unknown
-
2021
- 2021-06-25 CL CL2021001718A patent/CL2021001718A1/es unknown
-
2023
- 2023-10-05 CL CL2023002984A patent/CL2023002984A1/es unknown
-
2024
- 2024-04-18 JP JP2024067819A patent/JP2024105308A/ja not_active Withdrawn
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