JP2022517742A5 - - Google Patents
Info
- Publication number
- JP2022517742A5 JP2022517742A5 JP2021538378A JP2021538378A JP2022517742A5 JP 2022517742 A5 JP2022517742 A5 JP 2022517742A5 JP 2021538378 A JP2021538378 A JP 2021538378A JP 2021538378 A JP2021538378 A JP 2021538378A JP 2022517742 A5 JP2022517742 A5 JP 2022517742A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- strand comprises
- antisense
- sequence described
- chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024067819A JP2024105308A (ja) | 2018-12-28 | 2024-04-18 | Ｈｍｇｂ１発現を阻害するための組成物及び方法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862786287P | 2018-12-28 | 2018-12-28 | |
| US62/786,287 | 2018-12-28 | ||
| US201862787038P | 2018-12-31 | 2018-12-31 | |
| US62/787,038 | 2018-12-31 | ||
| US201962788111P | 2019-01-03 | 2019-01-03 | |
| US62/788,111 | 2019-01-03 | ||
| PCT/US2019/067883 WO2020139764A1 (en) | 2018-12-28 | 2019-12-20 | Compositions and methods for inhibiting hmgb1 expression |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024067819A Division JP2024105308A (ja) | 2018-12-28 | 2024-04-18 | Ｈｍｇｂ１発現を阻害するための組成物及び方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022517742A JP2022517742A (ja) | 2022-03-10 |
| JP2022517742A5 true JP2022517742A5 (https=) | 2023-02-24 |
Family
ID=71128894
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021538378A Pending JP2022517742A (ja) | 2018-12-28 | 2019-12-20 | Ｈｍｇｂ１発現を阻害するための組成物及び方法 |
| JP2024067819A Withdrawn JP2024105308A (ja) | 2018-12-28 | 2024-04-18 | Ｈｍｇｂ１発現を阻害するための組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024067819A Withdrawn JP2024105308A (ja) | 2018-12-28 | 2024-04-18 | Ｈｍｇｂ１発現を阻害するための組成物及び方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20220072024A1 (https=) |
| EP (1) | EP3883581A4 (https=) |
| JP (2) | JP2022517742A (https=) |
| KR (1) | KR20210126004A (https=) |
| CN (1) | CN113874025A (https=) |
| AU (1) | AU2019417585A1 (https=) |
| BR (1) | BR112021012516A2 (https=) |
| CA (1) | CA3124664A1 (https=) |
| CL (2) | CL2021001718A1 (https=) |
| IL (2) | IL284327B2 (https=) |
| MX (1) | MX2021007855A (https=) |
| SG (1) | SG11202106857VA (https=) |
| WO (1) | WO2020139764A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL271680B (en) | 2017-06-29 | 2022-09-01 | Dicerna Pharmaceuticals Inc | Compositions and methods for inhibiting hmgb1 expression |
| CN119183476A (zh) * | 2022-04-26 | 2024-12-24 | 上海拓界生物医药科技有限公司 | 氘代化学修饰和包含其的寡核苷酸 |
| TWI868755B (zh) | 2022-06-24 | 2025-01-01 | 丹麥商諾佛 儂迪克股份有限公司 | 抑制跨膜絲胺酸蛋白酶６（ｔｍｐｒｓｓ６）表現的組成物及方法 |
| WO2024061202A1 (zh) * | 2022-09-20 | 2024-03-28 | 北京福元医药股份有限公司 | 用于抑制hmgb1基因表达的双链核糖核酸及其修饰物、缀合物和用途 |
| WO2024233864A2 (en) * | 2023-05-10 | 2024-11-14 | Dicerna Pharmaceuticals, Inc. | Galnac-conjugated rnai oligonucleotides |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007076200A2 (en) * | 2005-11-28 | 2007-07-05 | Medimmune, Inc. | Antagonists of hmgb1 and/or rage and methods of use thereof |
| WO2007150071A1 (en) * | 2006-06-23 | 2007-12-27 | Myriad Genetics, Inc. | Gene amplifications and deletions |
| EP2455469A4 (en) * | 2009-07-16 | 2013-03-13 | Nec Software Ltd | FOR BINDING TO HMGB1 ABLE NUCLEIC ACID MOLECULE AND USE THEREOF |
| JP5686814B2 (ja) * | 2010-09-17 | 2015-03-18 | 独立行政法人科学技術振興機構 | Ｈｍｇｂタンパクによって仲介される免疫応答の活性化の抑制剤及びスクリーニング方法 |
| WO2012177639A2 (en) * | 2011-06-22 | 2012-12-27 | Alnylam Pharmaceuticals, Inc. | Bioprocessing and bioproduction using avian cell lines |
| AU2015330670B2 (en) * | 2014-10-10 | 2022-01-06 | Novo Nordisk Health Care Ag | Therapeutic inhibition of lactate dehydrogenase and agents therefor |
| DK3569711T3 (da) * | 2014-12-15 | 2021-02-22 | Dicerna Pharmaceuticals Inc | Ligandmodificerede dobbeltstrengede nukleinsyrer |
| WO2017079227A1 (en) * | 2015-11-05 | 2017-05-11 | University Of Connecticut | Compositions and methods for the treatment of liver fibrosis |
| HUE059718T2 (hu) * | 2016-09-02 | 2022-12-28 | Dicerna Pharmaceuticals Inc | 4'-foszfát analógok és azokat tartalmazó oligonukleotidok |
| IL271680B (en) * | 2017-06-29 | 2022-09-01 | Dicerna Pharmaceuticals Inc | Compositions and methods for inhibiting hmgb1 expression |
| EP3728593A1 (en) * | 2017-12-18 | 2020-10-28 | Alnylam Pharmaceuticals, Inc. | High mobility group box-1 (hmgb1) irna compositions and methods of use thereof |
-
2019
- 2019-12-20 SG SG11202106857VA patent/SG11202106857VA/en unknown
- 2019-12-20 CA CA3124664A patent/CA3124664A1/en active Pending
- 2019-12-20 BR BR112021012516-7A patent/BR112021012516A2/pt not_active Application Discontinuation
- 2019-12-20 WO PCT/US2019/067883 patent/WO2020139764A1/en not_active Ceased
- 2019-12-20 MX MX2021007855A patent/MX2021007855A/es unknown
- 2019-12-20 EP EP19902219.5A patent/EP3883581A4/en not_active Withdrawn
- 2019-12-20 IL IL284327A patent/IL284327B2/en unknown
- 2019-12-20 KR KR1020217023455A patent/KR20210126004A/ko not_active Withdrawn
- 2019-12-20 JP JP2021538378A patent/JP2022517742A/ja active Pending
- 2019-12-20 AU AU2019417585A patent/AU2019417585A1/en not_active Withdrawn
- 2019-12-20 CN CN201980093263.2A patent/CN113874025A/zh not_active Withdrawn
- 2019-12-20 US US17/309,860 patent/US20220072024A1/en not_active Abandoned
- 2019-12-20 IL IL313425A patent/IL313425A/en unknown
-
2021
- 2021-06-25 CL CL2021001718A patent/CL2021001718A1/es unknown
-
2023
- 2023-10-05 CL CL2023002984A patent/CL2023002984A1/es unknown
-
2024
- 2024-04-18 JP JP2024067819A patent/JP2024105308A/ja not_active Withdrawn
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