JP2022520653A5 - - Google Patents
Info
- Publication number
- JP2022520653A5 JP2022520653A5 JP2021547792A JP2021547792A JP2022520653A5 JP 2022520653 A5 JP2022520653 A5 JP 2022520653A5 JP 2021547792 A JP2021547792 A JP 2021547792A JP 2021547792 A JP2021547792 A JP 2021547792A JP 2022520653 A5 JP2022520653 A5 JP 2022520653A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- nucleotides
- strand
- sense strand
- antisense strand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962804410P | 2019-02-12 | 2019-02-12 | |
| US62/804,410 | 2019-02-12 | ||
| PCT/US2020/017129 WO2020167593A1 (en) | 2019-02-12 | 2020-02-07 | Methods and compositions for inhibiting expression of cyp27a1 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022520653A JP2022520653A (ja) | 2022-03-31 |
| JP2022520653A5 true JP2022520653A5 (https=) | 2023-04-13 |
Family
ID=69941447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021547792A Withdrawn JP2022520653A (ja) | 2019-02-12 | 2020-02-07 | Ｃｙｐ２７ａ１の発現を阻害するための方法及び組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20220186229A1 (https=) |
| EP (1) | EP3908661A1 (https=) |
| JP (1) | JP2022520653A (https=) |
| KR (1) | KR20210132661A (https=) |
| CN (1) | CN113692444A (https=) |
| AU (1) | AU2020221892A1 (https=) |
| BR (1) | BR112021015651A2 (https=) |
| CA (1) | CA3128059A1 (https=) |
| CL (2) | CL2021002120A1 (https=) |
| IL (1) | IL285367A (https=) |
| MX (1) | MX2021009754A (https=) |
| SG (1) | SG11202108532RA (https=) |
| WO (1) | WO2020167593A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2024269205A1 (en) * | 2023-05-11 | 2025-12-11 | Keymed Biosciences (Us) Inc. | Dsrna molecules for regulating masp2 gene activity |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2336887T5 (es) | 2000-03-30 | 2019-03-06 | Whitehead Inst Biomedical Res | Mediadores de interferencia por ARN específicos de secuencias de ARN |
| WO2002030952A2 (en) * | 2000-10-13 | 2002-04-18 | Genaissance Pharmaceuticals, Inc. | Haplotypes of the cyp27a1 gene |
| CA2429814C (en) | 2000-12-01 | 2014-02-18 | Thomas Tuschl | Rna interference mediating small rna molecules |
| US20050159378A1 (en) | 2001-05-18 | 2005-07-21 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA) |
| WO2003040395A2 (en) | 2001-11-07 | 2003-05-15 | Applera Corporation | Universal nucleotides for nucleic acid analysis |
| US20070265220A1 (en) | 2004-03-15 | 2007-11-15 | City Of Hope | Methods and compositions for the specific inhibition of gene expression by double-stranded RNA |
| WO2007030167A1 (en) | 2005-09-02 | 2007-03-15 | Nastech Pharmaceutical Company Inc. | Modification of double-stranded ribonucleic acid molecules |
| DK2341943T3 (en) | 2008-09-22 | 2019-02-25 | Dicerna Pharmaceuticals Inc | COMPOSITIONS AND METHODS OF SPECIFIC INHIBITION OF DSRNA REPRINT WITH MODIFICATIONS |
| US8691971B2 (en) | 2008-09-23 | 2014-04-08 | Scott G. Petersen | Self delivering bio-labile phosphate protected pro-oligos for oligonucleotide based therapeutics and mediating RNA interference |
| US20100249214A1 (en) | 2009-02-11 | 2010-09-30 | Dicerna Pharmaceuticals | Multiplex dicer substrate rna interference molecules having joining sequences |
| KR101728655B1 (ko) | 2008-12-18 | 2017-04-19 | 다이서나 파마수이티컬, 인크. | 유전자 발현의 특이적 억제를 위한 연장된 다이서 기질 제제 및 방법 |
| WO2011005860A2 (en) | 2009-07-07 | 2011-01-13 | Alnylam Pharmaceuticals, Inc. | 5' phosphate mimics |
| WO2011133871A2 (en) | 2010-04-22 | 2011-10-27 | Alnylam Pharmaceuticals, Inc. | 5'-end derivatives |
| AU2012328680A1 (en) | 2011-10-25 | 2014-05-01 | Ionis Pharmaceuticals, Inc. | Antisense modulation of GCCR expression |
| EP2928877B1 (en) | 2012-12-06 | 2020-01-22 | Merck Sharp & Dohme Corp. | Disulfide masked prodrug compositions and methods |
| CA2950960A1 (en) | 2014-06-06 | 2015-12-10 | Solstice Biologics, Ltd. | Polynucleotide constructs having bioreversible and non-bioreversible groups |
| DK3569711T3 (da) * | 2014-12-15 | 2021-02-22 | Dicerna Pharmaceuticals Inc | Ligandmodificerede dobbeltstrengede nukleinsyrer |
| KR101916583B1 (ko) * | 2017-04-20 | 2018-11-07 | 가천대학교 산학협력단 | 칼피르조밉을 유효성분으로 함유하는 담석증의 예방 또는 치료용 약학적 조성물 |
-
2020
- 2020-02-07 EP EP20713417.2A patent/EP3908661A1/en not_active Withdrawn
- 2020-02-07 KR KR1020217026888A patent/KR20210132661A/ko not_active Withdrawn
- 2020-02-07 BR BR112021015651-8A patent/BR112021015651A2/pt not_active Application Discontinuation
- 2020-02-07 CA CA3128059A patent/CA3128059A1/en active Pending
- 2020-02-07 JP JP2021547792A patent/JP2022520653A/ja not_active Withdrawn
- 2020-02-07 SG SG11202108532RA patent/SG11202108532RA/en unknown
- 2020-02-07 CN CN202080028344.7A patent/CN113692444A/zh not_active Withdrawn
- 2020-02-07 AU AU2020221892A patent/AU2020221892A1/en not_active Withdrawn
- 2020-02-07 WO PCT/US2020/017129 patent/WO2020167593A1/en not_active Ceased
- 2020-02-07 MX MX2021009754A patent/MX2021009754A/es unknown
- 2020-02-07 US US17/310,579 patent/US20220186229A1/en not_active Abandoned
-
2021
- 2021-08-04 IL IL285367A patent/IL285367A/en unknown
- 2021-08-11 CL CL2021002120A patent/CL2021002120A1/es unknown
-
2023
- 2023-12-27 CL CL2023003914A patent/CL2023003914A1/es unknown
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