BR112021015651A2 - Métodos e composições para inibir a expressão de cyp27a1 - Google Patents
Métodos e composições para inibir a expressão de cyp27a1 Download PDFInfo
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- BR112021015651A2 BR112021015651A2 BR112021015651-8A BR112021015651A BR112021015651A2 BR 112021015651 A2 BR112021015651 A2 BR 112021015651A2 BR 112021015651 A BR112021015651 A BR 112021015651A BR 112021015651 A2 BR112021015651 A2 BR 112021015651A2
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- oligonucleotide
- nucleotides
- length
- antisense strand
- cyp27a1
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| WO2011133871A2 (en) | 2010-04-22 | 2011-10-27 | Alnylam Pharmaceuticals, Inc. | 5'-end derivatives |
| JP2015501155A (ja) | 2011-10-25 | 2015-01-15 | アイシス ファーマシューティカルズ， インコーポレーテッド | Ｇｃｃｒ発現のアンチセンス調整 |
| EP2928877B1 (en) | 2012-12-06 | 2020-01-22 | Merck Sharp & Dohme Corp. | Disulfide masked prodrug compositions and methods |
| JP2017522046A (ja) | 2014-06-06 | 2017-08-10 | ソルスティス バイオロジクス，リミティッド | 生物可逆的および生物不可逆的基を有するポリヌクレオチド構築物 |
| JP7105065B2 (ja) * | 2014-12-15 | 2022-07-22 | ダイセルナ ファーマシューティカルズ， インコーポレイテッド | リガンド修飾二本鎖核酸 |
| KR101916583B1 (ko) * | 2017-04-20 | 2018-11-07 | 가천대학교 산학협력단 | 칼피르조밉을 유효성분으로 함유하는 담석증의 예방 또는 치료용 약학적 조성물 |
-
2020
- 2020-02-07 CN CN202080028344.7A patent/CN113692444A/zh not_active Withdrawn
- 2020-02-07 MX MX2021009754A patent/MX2021009754A/es unknown
- 2020-02-07 CA CA3128059A patent/CA3128059A1/en active Pending
- 2020-02-07 WO PCT/US2020/017129 patent/WO2020167593A1/en not_active Ceased
- 2020-02-07 SG SG11202108532RA patent/SG11202108532RA/en unknown
- 2020-02-07 KR KR1020217026888A patent/KR20210132661A/ko not_active Withdrawn
- 2020-02-07 AU AU2020221892A patent/AU2020221892A1/en not_active Withdrawn
- 2020-02-07 JP JP2021547792A patent/JP2022520653A/ja not_active Withdrawn
- 2020-02-07 EP EP20713417.2A patent/EP3908661A1/en not_active Withdrawn
- 2020-02-07 BR BR112021015651-8A patent/BR112021015651A2/pt not_active Application Discontinuation
- 2020-02-07 US US17/310,579 patent/US20220186229A1/en not_active Abandoned
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2021
- 2021-08-04 IL IL285367A patent/IL285367A/en unknown
- 2021-08-11 CL CL2021002120A patent/CL2021002120A1/es unknown
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2023
- 2023-12-27 CL CL2023003914A patent/CL2023003914A1/es unknown
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| MX2021009754A (es) | 2021-09-08 |
| IL285367A (en) | 2021-09-30 |
| US20220186229A1 (en) | 2022-06-16 |
| AU2020221892A1 (en) | 2021-08-19 |
| CL2021002120A1 (es) | 2022-04-01 |
| SG11202108532RA (en) | 2021-09-29 |
| WO2020167593A1 (en) | 2020-08-20 |
| CA3128059A1 (en) | 2020-08-20 |
| JP2022520653A (ja) | 2022-03-31 |
| KR20210132661A (ko) | 2021-11-04 |
| CN113692444A (zh) | 2021-11-23 |
| CL2023003914A1 (es) | 2024-07-12 |
| EP3908661A1 (en) | 2021-11-17 |
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