JPWO2020072546A5 - - Google Patents
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- JPWO2020072546A5 JPWO2020072546A5 JP2021542091A JP2021542091A JPWO2020072546A5 JP WO2020072546 A5 JPWO2020072546 A5 JP WO2020072546A5 JP 2021542091 A JP2021542091 A JP 2021542091A JP 2021542091 A JP2021542091 A JP 2021542091A JP WO2020072546 A5 JPWO2020072546 A5 JP WO2020072546A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- seq
- cells
- sequence
- solid tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025078264A JP2025131589A (ja) | 2018-10-01 | 2025-05-08 | 固形腫瘍を治療するための遺伝子操作しているγδ－Ｔ細胞及び遺伝子操作していないγδ－Ｔ細胞に関する組成物及び方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862739826P | 2018-10-01 | 2018-10-01 | |
| US62/739,826 | 2018-10-01 | ||
| PCT/US2019/054144 WO2020072546A2 (en) | 2018-10-01 | 2019-10-01 | COMPOSITIONS AND METHODS REGARDING ENGINEERED AND NON-ENGINEERED γδ -T CELLS FOR TREATMENT OF SOLID TUMORS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025078264A Division JP2025131589A (ja) | 2018-10-01 | 2025-05-08 | 固形腫瘍を治療するための遺伝子操作しているγδ－Ｔ細胞及び遺伝子操作していないγδ－Ｔ細胞に関する組成物及び方法 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022513321A JP2022513321A (ja) | 2022-02-07 |
| JP2022513321A5 JP2022513321A5 (https=) | 2022-10-11 |
| JPWO2020072546A5 true JPWO2020072546A5 (https=) | 2022-10-11 |
| JP7679298B2 JP7679298B2 (ja) | 2025-05-19 |
Family
ID=68296749
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021542091A Active JP7679298B2 (ja) | 2018-10-01 | 2019-10-01 | 固形腫瘍を治療するための遺伝子操作しているγδ－Ｔ細胞及び遺伝子操作していないγδ－Ｔ細胞に関する組成物及び方法 |
| JP2025078264A Pending JP2025131589A (ja) | 2018-10-01 | 2025-05-08 | 固形腫瘍を治療するための遺伝子操作しているγδ－Ｔ細胞及び遺伝子操作していないγδ－Ｔ細胞に関する組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025078264A Pending JP2025131589A (ja) | 2018-10-01 | 2025-05-08 | 固形腫瘍を治療するための遺伝子操作しているγδ－Ｔ細胞及び遺伝子操作していないγδ－Ｔ細胞に関する組成物及び方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20210388109A1 (https=) |
| EP (1) | EP3860716A2 (https=) |
| JP (2) | JP7679298B2 (https=) |
| KR (1) | KR20210087458A (https=) |
| CN (1) | CN113272016A (https=) |
| AU (1) | AU2019354395A1 (https=) |
| BR (1) | BR112021006254A2 (https=) |
| CA (1) | CA3115059A1 (https=) |
| EA (1) | EA202190915A1 (https=) |
| IL (1) | IL281943A (https=) |
| MX (1) | MX2021003744A (https=) |
| SG (1) | SG11202103234RA (https=) |
| WO (1) | WO2020072546A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11629340B2 (en) | 2017-03-03 | 2023-04-18 | Obsidian Therapeutics, Inc. | DHFR tunable protein regulation |
| CA3150224A1 (en) | 2019-09-10 | 2021-03-18 | Obsidian Therapeutics, Inc. | Ca2 compositions and methods for tunable regulation |
| EP4308133A4 (en) * | 2021-03-17 | 2025-01-22 | Myeloid Therapeutics, Inc. | MANIPULATED CHIMERIC FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF |
| CN121419997A (zh) * | 2023-06-14 | 2026-01-27 | 上海北恒生物科技有限公司 | 包含新型共刺激结构域的嵌合抗原受体及其用途 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2451493C (en) | 2001-06-22 | 2016-08-23 | Chugai Seiyaku Kabushiki Kaisha | Cell growth inhibitors containing anti-glypican 3 antibody |
| JP5139800B2 (ja) * | 2004-06-03 | 2013-02-06 | ノビミューン エスアー | 抗ｃｄ３抗体およびその使用方法 |
| CN1842540B (zh) | 2004-07-09 | 2012-07-04 | 中外制药株式会社 | 抗-磷脂酰肌醇蛋白聚糖3抗体 |
| AU2005336093B2 (en) | 2004-10-08 | 2011-02-24 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Adoptive immunotherapy with enhanced T lymphocyte survival |
| CN101068836B (zh) | 2004-10-26 | 2013-08-14 | 中外制药株式会社 | 糖链改变的抗磷脂酰肌醇聚糖3抗体 |
| US20070087005A1 (en) | 2005-10-14 | 2007-04-19 | Lazar Gregory A | Anti-glypican-3 antibody |
| CA2682093A1 (en) | 2007-03-29 | 2008-10-09 | Technion Research & Development Foundation Ltd. | Antibodies, methods and kits for diagnosing and treating melanoma |
| WO2010042490A1 (en) | 2008-10-06 | 2010-04-15 | Boston Medical Center Corporation | A single lentiviral vector system for induced pluripotent (ips) stem cells derivation |
| WO2010088160A1 (en) | 2009-01-28 | 2010-08-05 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | T cell receptors and related materials and methods of use |
| CN103635573B (zh) | 2011-05-19 | 2016-05-11 | 分子医学研究所 | 包含γδT细胞的淋巴细胞系、其组合物及生产方法 |
| WO2013070468A1 (en) * | 2011-11-08 | 2013-05-16 | The Trustees Of The University Of Pennsylvania | Glypican-3-specific antibody and uses thereof |
| CN103833852A (zh) * | 2012-11-23 | 2014-06-04 | 上海市肿瘤研究所 | 针对磷脂酰肌醇蛋白多糖-3和t细胞抗原的双特异性抗体 |
| CN104140974B (zh) | 2013-05-08 | 2017-09-29 | 科济生物医药（上海）有限公司 | 编码gpc‑3嵌合抗原受体蛋白的核酸及表达gpc‑3嵌合抗原受体蛋白的t淋巴细胞 |
| JP2016539929A (ja) * | 2013-10-25 | 2016-12-22 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 免疫療法のためのポリクローナルγδＴ細胞 |
| GB201506423D0 (en) * | 2015-04-15 | 2015-05-27 | Tc Biopharm Ltd | Gamma delta T cells and uses thereof |
| CN107075480A (zh) | 2014-07-09 | 2017-08-18 | Tc生物制药有限公司 | γδT细胞及其用途 |
| US10093746B2 (en) | 2014-09-04 | 2018-10-09 | The Trustees Of The University Of Pennsylvania | Glypican-3 antibody and uses thereof |
| MA40764A (fr) | 2014-09-26 | 2017-08-01 | Chugai Pharmaceutical Co Ltd | Agent thérapeutique induisant une cytotoxicité |
| JP2017529851A (ja) | 2014-09-26 | 2017-10-12 | ベイラー カレッジ オブ メディスンＢａｙｌｏｒ Ｃｏｌｌｅｇｅ Ｏｆ Ｍｅｄｉｃｉｎｅ | 養子免疫療法のためのグリピカン−３特異的キメラ抗原レセプター |
| WO2016081518A2 (en) | 2014-11-17 | 2016-05-26 | Adicet Bio, Inc. | Engineered gamma delta t-cells |
| CN105713881B (zh) | 2014-12-04 | 2019-12-06 | 科济生物医药（上海）有限公司 | 双靶向gpc3和asgpr1的转基因免疫效应细胞及其应用 |
| GB201507368D0 (en) * | 2015-04-30 | 2015-06-17 | Ucl Business Plc | Cell |
| NL2014935B1 (en) * | 2015-06-08 | 2017-02-03 | Applied Immune Tech Ltd | T cell receptor like antibodies having fine specificity. |
| AU2016274633B2 (en) | 2015-06-09 | 2022-04-21 | Gammadelta Therapeutics Ltd | Methods for the production of TCR gamma delta+ T cells |
| US12168061B2 (en) * | 2015-08-03 | 2024-12-17 | Crage Medical Co., Limited | Antibody against glypican-3 and application thereof |
| US20180258149A1 (en) * | 2015-09-17 | 2018-09-13 | Novartis Ag | Car t cell therapies with enhanced efficacy |
| WO2017083750A1 (en) | 2015-11-11 | 2017-05-18 | Intrexon Corporation | Compositions and methods for expression of multiple biologically active polypeptides from a single vector for treatment of cardiac conditions and other pathologies |
| KR20190003938A (ko) * | 2016-02-25 | 2019-01-10 | 셀 메디카 스위처란트 아게 | 면역치료를 위한 변형된 세포 |
| EP3454870A4 (en) * | 2016-05-12 | 2020-03-04 | Adicet Bio Inc. | METHOD FOR SELECTIVE EXPANSION OF GAMMA DELTA T CELL POPULATIONS AND COMPOSITIONS THEREOF |
| CN107523545A (zh) * | 2016-06-20 | 2017-12-29 | 上海细胞治疗研究院 | 一种高效稳定表达抗体的杀伤性细胞及其用途 |
| US20190262397A1 (en) * | 2016-07-26 | 2019-08-29 | Tessa Therapeutics Pte. Ltd. | Chimeric antigen receptor |
| BR112019013947A2 (pt) * | 2017-01-10 | 2020-02-11 | Yamaguchi University | Anticorpo, receptor de antígeno quimérico, célula imunocompetente, gene de anticorpo, vetor, célula hospedeira, método para detectar gpc3, e, kit para a detecção de gpc3. |
| GB201701332D0 (en) * | 2017-01-26 | 2017-03-15 | Tc Biopharm Ltd | Immune cells with modified metabolism and their use thereof |
| EP3580331B1 (en) * | 2017-02-08 | 2022-06-01 | Agency For Science, Technology And Research | Gamma delta t cells and a method of augmenting the tumoricidal activity of the same |
| IL270138B2 (en) * | 2017-04-26 | 2025-08-01 | Eureka Therapeutics Inc | Structures that specifically recognize glypican 3 and their uses |
| GB2562774A (en) | 2017-05-25 | 2018-11-28 | Mcdonald Michael | Genetic construct |
| AU2017418590A1 (en) * | 2017-06-14 | 2020-01-16 | Adicet Therapeutics, Inc. | Antibodies capable of binding HLA-A2/TyrD in an HLA restricted manner and uses thereof |
| EP3561053A1 (en) * | 2018-04-26 | 2019-10-30 | Baylor College of Medicine | Immune effector cells and molecular adaptors with an antigen cytokine complex for effective cancer immunotherapy |
| EP3784256A4 (en) * | 2018-04-27 | 2022-06-29 | Baylor College of Medicine | Car t cells with one or more interleukins |
| CN108588023B (zh) * | 2018-05-09 | 2020-02-14 | 河北森朗生物科技有限公司 | 一种生产嵌合抗原受体修饰的γδT细胞的方法 |
| JPWO2020017479A1 (ja) * | 2018-07-17 | 2021-08-02 | ノイルイミューン・バイオテック株式会社 | 抗ｇｐｃ３一本鎖抗体を含むｃａｒ |
-
2019
- 2019-10-01 CN CN201980077422.XA patent/CN113272016A/zh active Pending
- 2019-10-01 MX MX2021003744A patent/MX2021003744A/es unknown
- 2019-10-01 KR KR1020217013183A patent/KR20210087458A/ko active Pending
- 2019-10-01 EP EP19791021.9A patent/EP3860716A2/en active Pending
- 2019-10-01 AU AU2019354395A patent/AU2019354395A1/en active Pending
- 2019-10-01 WO PCT/US2019/054144 patent/WO2020072546A2/en not_active Ceased
- 2019-10-01 CA CA3115059A patent/CA3115059A1/en active Pending
- 2019-10-01 SG SG11202103234RA patent/SG11202103234RA/en unknown
- 2019-10-01 EA EA202190915A patent/EA202190915A1/ru unknown
- 2019-10-01 BR BR112021006254-8A patent/BR112021006254A2/pt unknown
- 2019-10-01 JP JP2021542091A patent/JP7679298B2/ja active Active
- 2019-10-01 US US17/281,886 patent/US20210388109A1/en active Pending
-
2021
- 2021-03-31 IL IL281943A patent/IL281943A/en unknown
-
2025
- 2025-05-08 JP JP2025078264A patent/JP2025131589A/ja active Pending
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