JPWO2020032228A5 - - Google Patents
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- Publication number
- JPWO2020032228A5 JPWO2020032228A5 JP2020535900A JP2020535900A JPWO2020032228A5 JP WO2020032228 A5 JPWO2020032228 A5 JP WO2020032228A5 JP 2020535900 A JP2020535900 A JP 2020535900A JP 2020535900 A JP2020535900 A JP 2020535900A JP WO2020032228 A5 JPWO2020032228 A5 JP WO2020032228A5
- Authority
- JP
- Japan
- Prior art keywords
- polynucleotide
- nucleotide sequence
- mir
- seq
- base sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108091033319 polynucleotide Proteins 0.000 claims 73
- 102000040430 polynucleotide Human genes 0.000 claims 73
- 239000002157 polynucleotide Substances 0.000 claims 73
- 239000002773 nucleotide Substances 0.000 claims 34
- 125000003729 nucleotide group Chemical group 0.000 claims 34
- 230000000295 complement effect Effects 0.000 claims 18
- 206010060862 Prostate cancer Diseases 0.000 claims 14
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 14
- 102000039446 nucleic acids Human genes 0.000 claims 13
- 108020004707 nucleic acids Proteins 0.000 claims 13
- 150000007523 nucleic acids Chemical class 0.000 claims 13
- 239000012634 fragment Substances 0.000 claims 12
- 230000014509 gene expression Effects 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 239000000439 tumor marker Substances 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- 108091038449 miR-1185-1 stem-loop Proteins 0.000 claims 3
- 108091026347 miR-1185-2 stem-loop Proteins 0.000 claims 3
- 108091038228 miR-1228 stem-loop Proteins 0.000 claims 3
- 108091091751 miR-17 stem-loop Proteins 0.000 claims 3
- 108091088515 miR-197 stem-loop Proteins 0.000 claims 3
- 108091044918 miR-320b stem-loop Proteins 0.000 claims 3
- 108091026895 miR-320b-1 stem-loop Proteins 0.000 claims 3
- 108091040992 miR-320b-2 stem-loop Proteins 0.000 claims 3
- 108091084120 miR-6076 stem-loop Proteins 0.000 claims 3
- 108091045240 miR-6819 stem-loop Proteins 0.000 claims 3
- 238000009396 hybridization Methods 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 108020004635 Complementary DNA Proteins 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 238000003499 nucleic acid array Methods 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018151952 | 2018-08-10 | ||
| JP2018151952 | 2018-08-10 | ||
| PCT/JP2019/031550 WO2020032228A1 (ja) | 2018-08-10 | 2019-08-09 | 前立腺がんの検出のためのキット、デバイス及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2020032228A1 JPWO2020032228A1 (ja) | 2021-08-26 |
| JPWO2020032228A5 true JPWO2020032228A5 (https=) | 2022-07-27 |
| JP7378739B2 JP7378739B2 (ja) | 2023-11-14 |
Family
ID=69414816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020535900A Active JP7378739B2 (ja) | 2018-08-10 | 2019-08-09 | 前立腺がんの検出のためのキット、デバイス及び方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US11535899B2 (https=) |
| EP (1) | EP3835434A4 (https=) |
| JP (1) | JP7378739B2 (https=) |
| WO (1) | WO2020032228A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12237082B2 (en) * | 2020-12-31 | 2025-02-25 | Flatiron Health, Inc. | Clinical trial matching system using inferred biomarker status |
| EP4382618A4 (en) * | 2021-08-02 | 2025-11-12 | Medical Ark Inc | CANINE CANCER DIAGNOSTIC METHOD |
| CN115838783A (zh) * | 2022-08-29 | 2023-03-24 | 郑州大学 | 一种β-CD作为增强剂的PGM检测miR-21试剂盒及其应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1969147B1 (en) * | 2006-01-05 | 2014-07-30 | The Ohio State University Research Foundation | microRNA-based methods for the diagnosis of stomach cancer |
| CN102027129B (zh) | 2008-02-28 | 2014-03-12 | 俄亥俄州立大学研究基金会 | 用于前列腺相关病症的诊断、预后和治疗的基于微rna的方法和组合物 |
| US7888035B2 (en) | 2008-10-30 | 2011-02-15 | Caris Mpi, Inc. | Methods for assessing RNA patterns |
| WO2010054386A2 (en) | 2008-11-10 | 2010-05-14 | Battelle Memorial Institute | Methods, compositions, and devices utilizing microrna to determine physiological conditions |
| EP2634266B1 (en) * | 2009-05-22 | 2015-10-14 | Asuragen, INC. | miRNA biomarkers of prostate disease |
| EP2341145A1 (en) | 2009-12-30 | 2011-07-06 | febit holding GmbH | miRNA fingerprint in the diagnosis of diseases |
| US9243246B2 (en) | 2010-08-24 | 2016-01-26 | Sirna Therapeutics, Inc. | Single-stranded RNAi agents containing an internal, non-nucleic acid spacer |
| JPWO2012063894A1 (ja) * | 2010-11-12 | 2014-05-12 | 国立大学法人愛媛大学 | マイクロrnaのアンチセンスオリゴヌクレオチドを含む組成物 |
| KR20140067001A (ko) | 2011-08-08 | 2014-06-03 | 카리스 라이프 사이언스 룩셈부르크 홀딩스, 에스.에이.알.엘. | 생물지표 조성물 및 방법 |
| WO2014071226A1 (en) | 2012-11-02 | 2014-05-08 | The Regents Of The University Of California | Methods and systems for determining a likelihood of adverse prostate cancer pathology |
| WO2014071205A1 (en) | 2012-11-02 | 2014-05-08 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for diagnosis, prognosis and treatment of hematological malignancies |
| US9416369B2 (en) * | 2012-12-18 | 2016-08-16 | University Of Washington Through Its Center For Commercialization | Methods and compositions to modulate RNA processing |
| JP2015039365A (ja) | 2013-08-23 | 2015-03-02 | 東レ株式会社 | 前立腺がんの検出用キットおよび検出方法 |
| CA2945531C (en) * | 2014-05-13 | 2018-01-30 | Zohar BARNETT-ITZHAKI | Mirna expression signature in the classification of thyroid tumors |
| KR102761162B1 (ko) * | 2014-06-12 | 2025-02-03 | 국립연구개발법인 고쿠리츠간켄큐센터 | 전립선암 검출 키트 또는 디바이스 및 검출 방법 |
| BR112016029583A2 (pt) * | 2014-06-18 | 2017-10-24 | Nat Cancer Ct | ?kit ou dispositivo para a detecção de câncer esofágico e método de detecção? |
| BR112016029634A2 (pt) * | 2014-06-18 | 2017-10-24 | Nat Cancer Ct | kit, dispositivo e método para a detecção de câncer de fígado |
| WO2016081941A1 (en) | 2014-11-21 | 2016-05-26 | Caris Science, Inc. | Oligonucleotide probes and uses thereof |
| KR101862080B1 (ko) | 2015-02-25 | 2018-07-04 | (주)바이오니아 | 마이크로 rna 를 유효 성분으로 포함하는 암 치료용 약학 조성물 |
| KR101569370B1 (ko) | 2015-05-27 | 2015-11-16 | 강건희 | 유무선 전화 수신환경 설정시스템. |
| JP6816577B2 (ja) | 2017-03-14 | 2021-01-20 | オムロン株式会社 | リーダ装置、無線タグ、情報提示システム |
| JP7165329B2 (ja) * | 2017-04-28 | 2022-11-04 | 東レ株式会社 | 卵巣腫瘍の検出のためのキット、デバイス及び方法 |
-
2019
- 2019-08-09 EP EP19847308.4A patent/EP3835434A4/en active Pending
- 2019-08-09 US US17/265,060 patent/US11535899B2/en active Active
- 2019-08-09 JP JP2020535900A patent/JP7378739B2/ja active Active
- 2019-08-09 WO PCT/JP2019/031550 patent/WO2020032228A1/ja not_active Ceased
-
2022
- 2022-11-17 US US17/988,959 patent/US11905565B2/en active Active
-
2024
- 2024-01-09 US US18/408,056 patent/US12252748B2/en active Active
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